(Q46307051)

21 December 2017

review article

1 reference

title

Mapping normal and cancer cell signalling networks: towards single-cell proteomics (English)

1 reference

21 December 2017

main subject

single-cell proteomics

1 reference

1

1 reference

21 December 2017

Garry P. Nolan

series ordinal

3

object named as

Garry P Nolan

1 reference

21 December 2017

author name string

Nikesh Kotecha

series ordinal

2

1 reference

21 December 2017

language of work or name

English

0 references

publication date

1 February 2006

1 reference

21 December 2017

published in

Nature Reviews Cancer

1 reference

21 December 2017

volume

6

1 reference

21 December 2017

issue

2

1 reference

21 December 2017

page(s)

146-155

1 reference

21 December 2017

Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

cites work

1 reference

Single cell profiling of potentiated phospho-protein networks in cancer cells.

21 January 2018

1 reference

Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients

21 January 2018

1 reference

Analyzing cellular biochemistry in terms of molecular networks

21 January 2018

1 reference

High-throughput mapping of a dynamic signaling network in mammalian cells

21 January 2018

1 reference

21 January 2018

The Hallmarks of Cancer

1 reference

Cell signaling and cancer

21 January 2018

1 reference

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

1 reference

Killing time for cancer cells

21 January 2018

1 reference

B cell development pathways

21 January 2018

1 reference

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

21 January 2018

1 reference

Causal protein-signaling networks derived from multiparameter single-cell data

21 January 2018

1 reference

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

21 January 2018

1 reference

Imatinib targets other than bcr/abl and their clinical relevance in myeloid disorders

21 January 2018

1 reference

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

21 January 2018

1 reference

STAT proteins: From normal control of cellular events to tumorigenesis

21 January 2018

1 reference

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis

21 January 2018

1 reference

STI571 (Gleevec) as a paradigm for cancer therapy

21 January 2018

1 reference

Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications

21 January 2018

1 reference

Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations

21 January 2018

1 reference

Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

21 January 2018

1 reference

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

1 reference

The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

21 January 2018

1 reference

The three Es of cancer immunoediting

21 January 2018

1 reference

c-Kit receptor (CD117) expression on myeloblasts and white blood cell counts in acute myeloid leukemia

21 January 2018

1 reference

Phenotypic characterization of the human myeloma cell growth fraction

21 January 2018

1 reference

21 January 2018

1 reference

Comparison of cell viability probes compatible with fixation and permeabilization for combined surface and intracellular staining in flow cytometry

21 January 2018

1 reference

Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis

21 January 2018

1 reference

Cell division rates of primary human precursor B cells in culture reflect in vivo rates

21 January 2018

1 reference

Flow cytometric immunophenotyping including Bcl-2 detection on fine needle aspirates in the diagnosis of reactive lymphadenopathy and non-Hodgkin's lymphoma

21 January 2018

1 reference

Quantitation of biological tumor markers (p53, c-myc, Ki-67 and DNA ploidy) by multiparameter flow cytometry in non-small-cell lung cancer

21 January 2018

1 reference

p53 status of newly established acute myeloid leukaemia cell lines

21 January 2018

1 reference

Monoclonal antibody specific for an activated RAS protein

21 January 2018

1 reference

Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.

21 January 2018

1 reference

Flow cytometric determination of glutathione in clinical samples.

21 January 2018

1 reference

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

21 January 2018

1 reference

Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas

21 January 2018

1 reference

Quantification and cytokine production of circulating lymphoid and myeloid cells in acute myelogenous leukaemia.

21 January 2018

1 reference

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

21 January 2018

1 reference

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis

21 January 2018

1 reference

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 January 2018

1 reference

HER2/neu as a predictive factor in breast cancer

21 January 2018

1 reference

The efficacy of Herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins

21 January 2018

1 reference

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

1 reference

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

21 January 2018

1 reference

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 January 2018

1 reference

Roots of clinical resistance to STI-571 cancer therapy

21 January 2018

1 reference

Targeting c-Kit mutations: basic science to novel therapies

21 January 2018

1 reference

PDGF receptors as cancer drug targets

21 January 2018

1 reference

The role of FLT3 in haematopoietic malignancies

21 January 2018

1 reference

Mechanisms of B-cell lymphoma pathogenesis

21 January 2018

1 reference

The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer

21 January 2018

1 reference

The new kid on the block(ade) of the IGF-1 receptor

21 January 2018

1 reference

Hedgehog signalling in cancer formation and maintenance

21 January 2018

1 reference

Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

1 reference

The discovery of receptor tyrosine kinases: targets for cancer therapy

21 January 2018

1 reference

Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

21 January 2018

1 reference

Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis

21 January 2018

1 reference

Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice

21 January 2018

1 reference

The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

NF1 tumor suppressor gene function: narrowing the GAP

21 January 2018

1 reference

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

21 January 2018

1 reference

c-MYC: more than just a matter of life and death

21 January 2018

1 reference

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

21 January 2018

1 reference

NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

1 reference

The p53 pathway: positive and negative feedback loops

21 January 2018

1 reference

The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

1 reference

Role of integrins in cell invasion and migration

21 January 2018

1 reference

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

Convergence of Wnt, beta-catenin, and cadherin pathways

21 January 2018

1 reference

21 January 2018

1 reference

Seventeen-colour flow cytometry: unravelling the immune system

21 January 2018

1 reference

Proliferative response of mantle cell lymphoma cells stimulated by CD40 ligation and IL-4

31 March 2020

1 reference

Flow cytometry detection of caspase 3 activation in preapoptotic leukemic cells

31 March 2020

1 reference

K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung

31 March 2020

1 reference

Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation

31 March 2020

1 reference

Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC1804

1 reference

21 December 2017

1 reference

21 December 2017