(Q46375029)

21 December 2017

title

Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteins (English)

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21 December 2017

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8

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21 December 2017

author name string

Mona Harnasch

1

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21 December 2017

Sandra Grau

2

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21 December 2017

Christian Behrends

3

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21 December 2017

Simon L Dove

4

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21 December 2017

Ann Hochschild

5

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21 December 2017

Maria-Karnina Iskandar

6

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21 December 2017

Weiming Xia

7

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21 December 2017

publication date

1 November 2004

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21 December 2017

Molecular Membrane Biology

published in

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21 December 2017

volume

21

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21 December 2017

issue

6

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21 December 2017

page(s)

373-383

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21 December 2017

Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins

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Analysis of the topology of a membrane protein by using a minimum number of alkaline phosphatase fusions

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The HtrA Family of Proteases

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

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The presenilins turned inside out: implications for their structures and functions

21 January 2018

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Conversion of the omega subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target

21 January 2018

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Activation of prokaryotic transcription through arbitrary protein-protein contacts.

21 January 2018

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Reconstitution of gamma-secretase activity

21 January 2018

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Proteolysis as a regulatory mechanism

21 January 2018

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Genetic analysis of membrane protein topology by a sandwich gene fusion approach

21 January 2018

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Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

21 January 2018

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Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

21 January 2018

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A portrait of Alzheimer secretases--new features and familiar faces

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A novel genetic system to detect protein-protein interactions

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Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter

21 January 2018

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Presenilin mutations line up along transmembrane alpha-helices.

21 January 2018

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Escherichia coli one- and two-hybrid systems for the analysis and identification of protein-protein interactions

21 January 2018

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The ins and outs of presenilin 1 membrane topology

21 January 2018

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γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

21 January 2018

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Evidence for a six-transmembrane domain structure of presenilin 1.

21 January 2018

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Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins

21 January 2018

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A genetic approach to analyzing membrane protein topology.

21 January 2018

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Mapping the APP/presenilin (PS) binding domains: the hydrophilic N-terminus of PS2 is sufficient for interaction with APP and can displace APP/PS1 interaction.

21 January 2018

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The protein-protein interaction map of Helicobacter pylori

21 January 2018

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Multiple effects of trehalose on protein folding in vitro and in vivo

21 January 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

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A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

21 January 2018

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Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

21 January 2018

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The role of presenilin cofactors in the gamma-secretase complex

21 January 2018

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

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The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins

21 January 2018

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Topogenic signals in integral membrane proteins

21 January 2018

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Biochemistry. Intramembrane proteases--mixing oil and water

21 January 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

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Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

21 January 2018

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

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Synthetic competition between cytoplasmic folding and translocation of a soluble membrane protein domain

21 January 2018

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10.1080/09687860400008429

21 January 2018

Identifiers

DOI

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21 December 2017

PubMed ID

15764367

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21 December 2017