(Q46547034)

English

A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension

scientific article published on 12 July 2013

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scholarly article

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension (English)

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

right ventricular hypertrophy

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inferred from title

author name string

Gopinath Sutendra

1

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Peter Dromparis

2

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Roxane Paulin

3

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Sotirios Zervopoulos

4

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Alois Haromy

5

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Jayan Nagendran

6

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Evangelos D Michelakis

7

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

publication date

12 July 2013

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

Journal of Molecular Medicine

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Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

91

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Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

11

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Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

1315-1327

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Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

https://scigraph.springernature.com/pub.10.1007/s00109-013-1059-4

0 references

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Right ventricular function in cardiovascular disease, part I: Anatomy, physiology, aging, and functional assessment of the right ventricle

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mitochondria in pulmonary vascular remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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The total length of myocytes and capillaries, and total number of myocyte nuclei in the rat heart are time-dependently increased by growth hormone.

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Making or breaking the heart: from lineage determination to morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Noradrenaline, atrial natriuretic peptide, bombesin and neurotensin in myocardium and blood of rats in congestive cardiac failure

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Acetylation is indispensable for p53 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Animal models of chronic heart failure

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Increased glycolytic metabolism in cardiac hypertrophy and congestive failure

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https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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Increased p53 protein expression in human failing myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

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ATP-citrate lyase links cellular metabolism to histone acetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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Hypoxia, HIF1 and glucose metabolism in the solid tumour

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Right ventricular function in cardiovascular disease, part II: pathophysiology, clinical importance, and management of right ventricular failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The monocrotaline model of pulmonary hypertension in perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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Carvedilol decreases elevated oxidative stress in human failing myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Right ventricular ischemia in patients with primary pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

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Increased [18F]fluorodeoxyglucose accumulation in right ventricular free wall in patients with pulmonary hypertension and the effect of epoprostenol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carvedilol inhibits pressure-induced increase in oxidative stress in coronary smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversity of the pyruvate dehydrogenase kinase gene family in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00109-013-1059-4

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/23846254

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