(Q48568146)

12 February 2018

title

Nitric oxide-producing microglia mediate thrombin-induced degeneration of dopaminergic neurons in rat midbrain slice culture (English)

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12 February 2018

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5

Akinori Akaike

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12 February 2018

author name string

Hiroshi Katsuki

1

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12 February 2018

Mitsugi Okawara

2

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12 February 2018

Haruki Shibata

3

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12 February 2018

Toshiaki Kume

4

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12 February 2018

language of work or name

English

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publication date

21 April 2006

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12 February 2018

Journal of Neurochemistry

published in

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12 February 2018

volume

97

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12 February 2018

issue

5

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12 February 2018

page(s)

1232-1242

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12 February 2018

Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia.

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1 reference

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Thrombin induces nigral dopaminergic neurodegeneration in vivo by altering expression of death-related proteins

21 January 2018

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Thrombin-induced oxidative stress contributes to the death of hippocampal neurons in vivo: role of microglial NADPH oxidase.

21 January 2018

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Chronic activation of ERK and neurodegenerative diseases.

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Signal transduction by the JNK group of MAP kinases

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Mechanisms of oxygen glucose deprivation-induced glutamate release from cerebrocortical slice cultures

21 January 2018

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Mixed-lineage kinase control of JNK and p38 MAPK pathways

21 January 2018

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Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus.

21 January 2018

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Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons.

21 January 2018

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Involvement of inducible nitric oxide synthase in inflammation-induced dopaminergic neurodegeneration

21 January 2018

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Oxidative stress in Parkinson's disease

21 January 2018

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Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2.

21 January 2018

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Microglia: a sensor for pathological events in the CNS

21 January 2018

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The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse

21 January 2018

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Thrombin-activated microglia contribute to death of dopaminergic neurons in rat mesencephalic cultures: dual roles of mitogen-activated protein kinase signaling pathways

21 January 2018

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A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

21 January 2018

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Microglia promote the death of developing Purkinje cells

21 January 2018

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Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

21 January 2018

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Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

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21 January 2018

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Participation of protease-activated receptor-1 in thrombin-induced microglial activation

21 January 2018

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Rapid tau aggregation and delayed hippocampal neuronal death induced by persistent thrombin signaling

21 January 2018

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Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

21 January 2018

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The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?

21 January 2018

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Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

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Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration?

21 January 2018

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Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B

21 January 2018

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10.1111/J.1471-4159.2006.03752.X

21 January 2018

Identifiers

DOI

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12 February 2018

1 reference

12 February 2018