(Q48592402)

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19 January 2020

title

Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy (English)

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19 January 2020

10

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19 January 2020

Rainer von Coelln

1

1 reference

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19 January 2020

author name string

Bobby Thomas

2

1 reference

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19 January 2020

Shaida A Andrabi

3

1 reference

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19 January 2020

Kah Leong Lim

4

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19 January 2020

Joseph M Savitt

5

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19 January 2020

Roya Saffary

6

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19 January 2020

Wanda Stirling

7

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19 January 2020

Kristy Bruno

8

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19 January 2020

Ellen J Hess

9

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19 January 2020

Valina L Dawson

11

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19 January 2020

Ted M Dawson

12

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19 January 2020

language of work or name

English

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publication date

1 April 2006

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19 January 2020

published in

Journal of Neuroscience

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19 January 2020

volume

26

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19 January 2020

issue

14

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19 January 2020

page(s)

3685-3696

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Degradation of alpha-synuclein by proteasome

19 January 2020

cites work

1 reference

12 December 2020

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

1 reference

12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

12 December 2020

A Drosophila model of Parkinson's disease

1 reference

12 December 2020

alpha-Synuclein immunoreactivity in dementia with Lewy bodies: morphological staging and comparison with ubiquitin immunostaining

1 reference

12 December 2020

Association between early-onset Parkinson's disease and mutations in the parkin gene

1 reference

12 December 2020

Neuropathology in mice expressing human alpha-synuclein

1 reference

12 December 2020

Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration

1 reference

12 December 2020

Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies

1 reference

12 December 2020

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

12 December 2020

Lewy body variant of Alzheimer's disease: alpha-synuclein in dystrophic neurites of A beta plaques.

1 reference

12 December 2020

The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.

1 reference

12 December 2020

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

1 reference

12 December 2020

Alpha-synuclein and neurodegenerative diseases

1 reference

12 December 2020

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

12 December 2020

Alpha-synuclein has an altered conformation and shows a tight intermolecular interaction with ubiquitin in Lewy bodies.

1 reference

12 December 2020

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

1 reference

12 December 2020

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

12 December 2020

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

12 December 2020

Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions

1 reference

12 December 2020

Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

1 reference

12 December 2020

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

1 reference

12 December 2020

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

12 December 2020

Rare genetic mutations shed light on the pathogenesis of Parkinson disease

1 reference

12 December 2020

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

1 reference

12 December 2020

Parkin: a multipurpose neuroprotective agent?

1 reference

12 December 2020

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

1 reference

12 December 2020

Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies

1 reference

12 December 2020

Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.

1 reference

12 December 2020

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

1 reference

12 December 2020

Molecular Pathways of Neurodegeneration in Parkinson's Disease

1 reference

12 December 2020

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

12 December 2020

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

1 reference

12 December 2020

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

1 reference

12 December 2020

Loss of locus coeruleus neurons and reduced startle in parkin null mice

1 reference

12 December 2020

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

1 reference

12 December 2020

Parkin-associated Parkinson's disease

1 reference

12 December 2020

Ubiquitination of alpha-synuclein.

1 reference

12 December 2020

Unaltered alpha-synuclein blood levels in juvenile Parkinsonism with a parkin exon 4 deletion.

1 reference

12 December 2020

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

12 December 2020

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

1 reference

12 December 2020

Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease

1 reference

12 December 2020

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

1 reference

12 December 2020

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

1 reference

12 December 2020

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

12 December 2020

Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input

1 reference

12 December 2020

Familial juvenile parkinsonism: clinical and pathologic study in a family.

1 reference

12 December 2020

New stereological methods for counting neurons

1 reference

12 December 2020

Neuropathology of Parkinson's disease

1 reference

12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

12 December 2020

Alpha-synuclein in Lewy bodies

1 reference

12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

12 December 2020

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1 reference

12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

12 December 2020

Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity.

1 reference

12 December 2020

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

12 December 2020

Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q.

1 reference

12 December 2020

Parkinson's disease. First of two parts

1 reference

12 December 2020

10.1523/JNEUROSCI.0414-06.2006

Identifiers

DOI

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19 January 2020

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19 January 2020

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