(Q50066011)

24 February 2018

title

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. (English)

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24 February 2018

author

David Casero

8

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24 February 2018

Mete Civelek

13

object named as

Mete Civelek

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24 February 2018

18

Aldons J Lusis

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24 February 2018

23

Peter Tontonoz

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24 February 2018

19

Julian Whitelegge

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24 February 2018

author name string

Tamer Sallam

1

1 reference

24 February 2018

Marius Jones

2

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24 February 2018

Brandon J Thomas

3

1 reference

24 February 2018

Xiaohui Wu

4

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24 February 2018

Thomas Gilliland

5

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24 February 2018

Kevin Qian

6

1 reference

24 February 2018

Ascia Eskin

7

1 reference

24 February 2018

Zhengyi Zhang

9

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24 February 2018

Jaspreet Sandhu

10

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24 February 2018

David Salisbury

11

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24 February 2018

Prashant Rajbhandari

12

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24 February 2018

Cynthia Hong

14

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24 February 2018

Ayaka Ito

15

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24 February 2018

Xin Liu

16

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24 February 2018

Bence Daniel

17

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24 February 2018

Laszlo Nagy

20

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24 February 2018

Antonio Castrillo

21

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24 February 2018

Stephen Smale

22

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24 February 2018

language of work or name

English

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publication date

12 February 2018

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24 February 2018

published in

Nature Medicine

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24 February 2018

Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP.

volume

24

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issue

3

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page(s)

304-312

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing.

2 November 2018

1 reference

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Local regulation of gene expression by lncRNA promoters, transcription and splicing.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Unique features of long non-coding RNA biogenesis and function

2 November 2018

1 reference

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NONCODE 2016: an informative and valuable data source of long non-coding RNAs.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Genome-wide analysis of enhancer RNA in gene regulation across 12 mouse tissues

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Systematic discovery of Xist RNA binding proteins

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

HDL cholesterol efflux capacity and incident cardiovascular events

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The central role of EED in the orchestration of polycomb group complexes.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Laser capture microdissection for analysis of macrophage gene expression from atherosclerotic lesions

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

STAR: ultrafast universal RNA-seq aligner

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

An integrated encyclopedia of DNA elements in the human genome

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Genome regulation by long noncoding RNAs.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Molecular mechanisms of long noncoding RNAs

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Histone H3K27ac separates active from poised enhancers and predicts developmental state

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Long noncoding RNA as modular scaffold of histone modification complexes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

GREAT improves functional interpretation of cis-regulatory regions

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Inflammation in atherosclerosis: from pathophysiology to practice

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

TopHat: discovering splice junctions with RNA-Seq

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Liver X receptors as integrators of metabolic and inflammatory signaling

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Millisecond-timescale, genetically targeted optical control of neural activity

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Coordinate regulation of transcription and splicing by steroid receptor coregulators

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839972

2 November 2018

Identifiers

DOI

10.1038/NM.4479

1 reference

24 February 2018

PMC publication ID

5839972

0 references

1 reference

24 February 2018