(Q50420723)

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AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy.

scientific article published on 5 March 2018

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scholarly article

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Europe PubMed Central

13 March 2018

http://europepmc.org/abstract/MED/29508283

AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy. (English)

1 reference

Europe PubMed Central

13 March 2018

http://europepmc.org/abstract/MED/29508283

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Valentina Latina

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6 June 2020

Giuseppina Amadoro

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6 June 2020

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A Borreca

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V Corsetti

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M Ammassari-Teule

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publication date

5 March 2018

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http://europepmc.org/abstract/MED/29508283

Molecular Neurobiology

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6 June 2020

8124-8153

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6 June 2020

https://scigraph.springernature.com/pub.10.1007/s12035-018-0974-3

0 references

Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

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Normal anatomy and neurophysiology of the hippocampal formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

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The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

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Regional synaptic pathology in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

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CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological stageing of Alzheimer-related changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods of estimation of spine density--are spines evenly distributed throughout the dendritic field?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Loss of dendritic spines in Alzheimer's disease]

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down's syndrome and Alzheimer's disease: dendritic spine counts in the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Destrin, a mammalian actin-depolymerizing protein, is closely related to cofilin. Cloning and expression of porcine brain destrin cDNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic pathology in Alzheimer's disease: relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 allele.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tau protein in human cerebrospinal fluid in Alzheimer's disease consists of proteolytically derived fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paired-pulse facilitation and depression at unitary synapses in rat hippocampus: quantal fluctuation affects subsequent release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

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Actin dynamics in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

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Continuous infusion of beta-amyloid protein into the rat cerebral ventricle induces learning impairment and neuronal and morphological degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role of cofilin/destrin in reorganization of actin cytoskeleton in response to stresses and cell stimuli.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity of release probability, facilitation, and depletion at central synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofilin promotes rapid actin filament turnover in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired recognition memory in patients with lesions limited to the hippocampal formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Very short-term plasticity in hippocampal synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for vibratome sectioning of Golgi-Cox stained whole rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitation, augmentation and potentiation at central synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death or synaptic loss in Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective changes of calcineurin (protein phosphatase 2B) activity in Alzheimer's disease cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between magnitude of damage to the hippocampus and impaired recognition memory in monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintained synaptophysin immunoreactivity in Tg2576 transgenic mice during aging: correlations with cognitive impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of candidates for vesicular glutamate transporters in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mouse: genetics meets behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau is essential to beta -amyloid-induced neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of CREB function in brain leads to neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-related synapse loss in the cingulate cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the understanding of the role of synaptic proteins in Alzheimer's Disease and other neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease is a synaptic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Associative memory formation increases the observation of dendritic spines in the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling from synapse to nucleus: the logic behind the mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral profiles of inbred strains on novel olfactory, spatial and emotional tests for reference memory in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subicular Dendritic Arborization in Alzheimer's Disease Correlates with Neurofibrillary Tangle Density

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathology of presynaptic proteins in Alzheimer's disease: more than simple loss of terminals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the delay-dependent involvement of the hippocampus in object recognition memory.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendrite and dendritic spine alterations in Alzheimer models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-beta1 signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spine architecture and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid pathology progresses in a neurotransmitter-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of dendritic spine morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular tau is toxic to neuronal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-related alterations in synaptic density: neocortex and hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial relationship between synapse loss and beta-amyloid deposition in Tg2576 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of depolymerization and severing of actin filaments and its significance in cytoskeletal dynamics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and cleavage of tau in non-AD tauopathies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal atrophy and disconnection in incipient and mild Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of tau in cerebrospinal fluid using mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spine loss and synaptic alterations in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropsychological assessment of dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread changes in dendritic spines in a model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Truncation of tau protein and its pathological significance in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-occurrence of Alzheimer's disease ß-amyloid and τ pathologies at synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin-kinases: modulators of neuronal development and plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factors in long-term memory and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic pathology in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics and consequences of muscarinic receptor activation by tau protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience-dependent structural synaptic plasticity in the mammalian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of donepezil on amyloid-beta and synapse density in the Tg2576 mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of long-term dendritic spine alterations in Alzheimer disease models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stably maintained dendritic spines are associated with lifelong memories

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid formation and selective stabilization of synapses for enduring motor memories

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular network analysis suggests aberrant CREB-mediated gene regulation in the Alzheimer disease hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural dynamics of dendritic spines in memory and cognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau reduction prevents Abeta-induced defects in axonal transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Volumetric MRI and MRS provide sensitive measures of Alzheimer's disease neuropathology in inducible Tau transgenic mice (rTg4510).

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium signalling and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking Effects of Human Tau on Squid Giant Synapse Transmission and Its Prevention by T-817 MA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing CREB function in the CA1 region of dorsal hippocampus rescues the spatial memory deficits in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implicating calpain in tau-mediated toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: synapses gone cold

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The novel object recognition memory: neurobiology, test procedure, and its modifications

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB-regulated transcription coactivator 1-dependent transcription in Alzheimer's disease mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer mechanisms and therapeutic strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Fos expression reveals aberrant neural network activity during cued fear conditioning in APPswe transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Object recognition testing: methodological considerations on exploration and discrimination measures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Looking for novel functions of tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid plaque formation precedes dendritic spine loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic alterations in the rTg4510 mouse model of tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer’s Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo cross-linking reveals principally oligomeric forms of α-synuclein and β-synuclein in neurons and non-neural cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vulnerable neural systems and the borderland of brain aging and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer disease: Aβ-independent processes-rethinking preclinical AD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau pathology and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for tau at the synapse in Alzheimer's disease pathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Object recognition test in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule-associated protein tau is essential for long-term depression in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sources of extracellular tau and its signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of tau-induced synaptic transmission pathology by paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β-Amyloid pathology alters neural network activation during retrieval of contextual fear memories in a mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau acts as a mediator for Alzheimer's disease-related synaptic deficits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reliable and durable Golgi staining of brain tissue from human autopsies and experimental animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid levels of a 20-22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intersection of amyloid beta and tau at synapses in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memory deficits correlate with tau and spine pathology in P301S MAPT transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal activity-driven transcriptome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo measurement of glutamate loss is associated with synapse loss in a mouse model of tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A framework to understand the variations of PSD-95 expression in brain aging and in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aβ Influences Cytoskeletal Signaling Cascades with Consequences to Alzheimer's Disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human secreted tau increases amyloid-beta production

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of disease-related cognitive impairments using the novel object recognition (NOR) task in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of α-synuclein from human brain reveals an instability of endogenous multimers as the protein approaches purity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau phosphorylation at serine 396 residue is required for hippocampal LTD

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-tau antibody reduces insoluble tau and decreases brain atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau immunotherapy for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca(++) dysregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of cofilin in development and its mechanisms of regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Object recognition test for studying cognitive impairments in animal models of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Isolation of Nuclei from Cells In Vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium/calmodulin-dependent kinase II and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Amyloid Beta Accumulation Disrupts Hippocampal CRTC1-Dependent Gene Expression and Cognitive Function in a Rat Model of Alzheimer Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Immediate-Early Genes in Synaptic Plasticity and Neuronal Ensembles Underlying the Memory Trace

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suspected non-Alzheimer disease pathophysiology--concept and controversy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau pathology-mediated presynaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of microRNA-34a in Alzheimer's disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state network activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Neurotoxic TAU45-230 Fragment Accumulates in Upper and Lower Motor Neurons in Amyotrophic Lateral Sclerosis Subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graded fear generalization enhances the level of cfos-positive neurons specifically in the basolateral amygdala

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunization targeting the N-terminal region of phosphorylated tau (residues 68-71) improves spatial memory in okadaic acid induced tauopathy model rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau passive immunization inhibits not only tau but also Aβ pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau-mediated synaptic damage in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic Compensation as a Probable Cause of Prolonged Mild Cognitive Impairment in Alzheimer's Disease: Implications from a Transgenic Mouse Model of the Disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered Synapse Stability in the Early Stages of Tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte dysfunction in Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Exceptional Vulnerability of Humans to Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau association with synaptic vesicles causes presynaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic Impairment in Alzheimer's Disease: A Dysregulated Symphony

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of TauC3 antibody and demonstration of its potential to block tau propagation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial contributions to neurodegeneration in tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual Mechanism of Toxicity for Extracellular Injection of Tau Oligomers versus Monomers in Human Tau Mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29508283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-018-0974-3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29508283%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

release_b6ikt5nljvhrrh3c2xbw47bl7e

1 reference

https://api.fatcat.wiki/v0/release/b6ikt5nljvhrrh3c2xbw47bl7e

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29508283%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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