(Q33640390)

28472993

28 July 2017

title

Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency (English)

1 reference

28 July 2017

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Michael G Agadjanyan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Karen Zagorski

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Irina Petrushina

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Hayk Davtyan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Konstantin Kazarian

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Maxim Antonenko

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Joy Davis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Charles Bon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

David H Cribbs

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Anahit Ghochikyan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

5 May 2017

1 reference

28472993

Molecular Neurodegeneration

28 July 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5418694/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Tau passive immunization inhibits not only tau but also Aβ pathology

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Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation.

21 June 2018

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Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules

21 June 2018

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Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry

21 June 2018

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Brain Uptake of Neurotherapeutics after Intranasal versus Intraperitoneal Delivery in Mice.

21 June 2018

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Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

21 June 2018

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Passive Immunization in JNPL3 Transgenic Mice Using an Array of Phospho-Tau Specific Antibodies

21 June 2018

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A fresh perspective from immunologists and vaccine researchers: active vaccination strategies to prevent and reverse Alzheimer's disease

21 June 2018

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Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake

21 June 2018

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Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.

21 June 2018

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Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models

21 June 2018

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Tau immunotherapy for Alzheimer's disease

21 June 2018

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Anti-tau antibody reduces insoluble tau and decreases brain atrophy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice

21 June 2018

1 reference

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First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model

21 June 2018

1 reference

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Proteopathic tau seeding predicts tauopathy in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Characterization and screening of IgG binding to the neonatal Fc receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Amyloid-ß-directed immunotherapy for Alzheimer's disease

21 June 2018

1 reference

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Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates

21 June 2018

1 reference

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Active immunotherapy options for Alzheimer's disease

21 June 2018

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Alzheimer disease therapy--moving from amyloid-β to tau.

21 June 2018

1 reference

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Antibody uptake into neurons occurs primarily via clathrin-dependent Fcγ receptor endocytosis and is a prerequisite for acute tau protein clearance.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Two novel Tau antibodies targeting the 396/404 region are primarily taken up by neurons and reduce Tau protein pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Epitope-based DNA vaccine for Alzheimer's disease: translational study in macaques

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Formation and propagation of tau oligomeric seeds

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tau passive immunotherapy in mutant P301L mice: antibody affinity versus specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

"Prion-like" templated misfolding in tauopathies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Brain transit and ameliorative effects of intranasally delivered anti-amyloid-β oligomer antibody in 5XFAD mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Refinement of a DNA based Alzheimer's disease epitope vaccine in rabbits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tau oligomers and tau toxicity in neurodegenerative disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tau as a therapeutic target in neurodegenerative disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Trans-cellular propagation of Tau aggregation by fibrillar species

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Targeting Beta amyloid: a clinical review of immunotherapeutic approaches in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Immunotherapy for tauopathies.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Amyloid-β and tau--a toxic pas de deux in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Preparation and characterization of neurotoxic tau oligomers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Prion-like mechanisms in neurodegenerative diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Axonal transport defects in neurodegenerative diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Transmission and spreading of tauopathy in transgenic mouse brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Propagation of tau misfolding from the outside to the inside of a cell.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Structural principles of tau and the paired helical filaments of Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Immunogenicity of engineered antibodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Apoptotic effect of caspase-3 cleaved tau in hippocampal neurons and its potentiation by tau FTDP-mutation N279K

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Tau polymerization: role of the amino terminus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Correlations of synaptic and pathological markers with cognition of the elderly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Global hairpin folding of tau in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Human secreted tau increases amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Diagnostic criteria for neuropathologic assessment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-017-0172-1

Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418694

Immunotherapy for Alzheimer's disease

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28472993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S13024-017-0172-1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28472993%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

28472993

1 reference