(Q52005155)

19 April 2018

title

Antigen receptor regulation of phosphoinositide-dependent kinase 1 pathways during thymocyte development. (English)

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3

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author name string

Heather J Hinton

series ordinal

1

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Rosemary G Clarke

series ordinal

2

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language of work or name

English

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publication date

28 September 2006

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published in

FEBS Letters

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volume

580

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issue

25

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page(s)

5845-5850

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Development of alphabeta T cells in the human thymus

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The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

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PDK1, the master regulator of AGC kinase signal transduction

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

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On the brink of becoming a T cell.

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development

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Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

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Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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21 January 2018

Identifiers

DOI

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19 April 2018

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19 April 2018