(Q52425308)

1 May 2018

title

Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL. (English)

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1 May 2018

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7

Martin Schrappe

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1 May 2018

Arend von Stackelberg

9

object named as

Arend von Stackelberg

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1 May 2018

Martin Stanulla

8

object named as

Martin Stanulla

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1 May 2018

author name string

Scott McComb

1

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1 May 2018

Júlia Aguadé-Gorgorió

2

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1 May 2018

Lena Harder

3

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1 May 2018

Blerim Marovca

4

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1 May 2018

Gunnar Cario

5

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1 May 2018

Cornelia Eckert

6

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1 May 2018

Jean-Pierre Bourquin

10

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1 May 2018

Beat C Bornhauser

11

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1 May 2018

language of work or name

English

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publication date

1 May 2016

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1 May 2018

Science Translational Medicine

published in

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1 May 2018

volume

8

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1 May 2018

issue

339

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1 May 2018

page(s)

339ra70

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1 May 2018

How I treat acute lymphoblastic leukemia in older adolescents and young adults

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Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

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Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.

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Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.

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Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

21 January 2018

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Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models

21 January 2018

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21 January 2018

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Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment

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Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.

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21 January 2018

Identifiers

DOI

1 reference

1 May 2018

1 reference

1 May 2018