(Q53630734)

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Phosphoinositide-dependent kinase l (PDK1) haplo-insufficiency inhibits production of alpha/beta (alpha/beta) but not gamma delta (gamma/delta) T lymphocytes.

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

Phosphoinositide-dependent kinase l (PDK1) haplo-insufficiency inhibits production of alpha/beta (alpha/beta) but not gamma delta (gamma/delta) T lymphocytes. (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

Doreen Cantrell

4

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

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April P Kelly

1

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

Heather J Hinton

2

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

Rosemary G Clarke

3

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

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publication date

15 March 2006

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

580

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

8

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

2135-2140

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

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21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Essential role of PDK1 in regulating cell size and development in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Development of alphabeta T cells in the human thymus

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Gammadelta T cell development--having the strength to get there

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

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Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice

1 reference

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Regulation of thymocyte differentiation: pre-TCR signals and beta-selection

1 reference

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21 January 2018

Regulation of thymocyte development from immature progenitors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

On the brink of becoming a T cell.

1 reference

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21 January 2018

Dendritic cell potentials of early lymphoid and myeloid progenitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Commitment to the T cell receptor-alpha beta or -gamma delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Positive and negative selection of T cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Thymic selection revisited: how essential is it?

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

The regulation of CD4 and CD8 coreceptor gene expression during T cell development

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Signaling checkpoints during the development of T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Signals involved in gamma/delta T cell versus alpha/beta T cell lineage commitment

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Notch1 and T-cell development: insights from conditional knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Lymphotoxin-mediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

PDK1 and PKB/Akt: ideal targets for development of new strategies to structure-based drug design

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Regulation of cutaneous malignancy by gammadelta T cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Age-dependent requirement for gammadelta T cells in the primary but not secondary protective immune response against an intestinal parasite

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Immunoregulation in the tissues by gammadelta T cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

Immunosurveillance by gammadelta T cells: focus on the murine system

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.03.022

21 January 2018

In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development

1 reference

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21 January 2018

Identifiers

10.1016/J.FEBSLET.2006.03.022

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16563390

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