(Q56992289)

1

0 references

R Schwaha

2

0 references

O Krämer

3

0 references

P Ettmayer

4

0 references

Eric EJ Haaksma

Expert Opinion on Drug Metabolism & Toxicology

5

0 references

language of work or name

English

0 references

publication date

24 August 2008

0 references

published in

0 references

volume

4

0 references

issue

9

0 references

page(s)

1167-1180

0 references

cites work

Multidrug resistance in cancer: role of ATP-dependent transporters

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Mining our ABCs: pharmacogenomic approach for evaluating transporter function in cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

The importance of drug-transporting P-glycoproteins in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

MDR- and CYP3A4-mediated drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Medicinal importance of grapefruit juice and its interaction with various drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Hepatobiliary transporters and drug-induced cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Targeting multidrug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Structure-activity relationship studies of propafenone analogs based on P-glycoprotein ATPase activity measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Evaluation of drug interactions with P-glycoprotein in drug discovery: in vitro assessment of the potential for drug-drug interactions with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Design, synthesis, cytoselective toxicity, structure-activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Tamoxifen aziridine, a novel affinity probe for P-glycoprotein in multidrug resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Molecule-pharmacophore superpositioning and pattern matching in computational drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Pharmacophore-based discovery of ligands for drug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Structural characteristics of compounds that modulate P-glycoprotein-associated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

A general pattern for substrate recognition by P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

A computational ensemble pharmacophore model for identifying substrates of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Characterization of two pharmacophores on the multidrug transporter P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Lead identification for modulators of multidrug resistance based on in silico screening with a pharmacophoric feature model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Rapid Identification of P-glycoprotein Substrates and Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Significance analysis and multiple pharmacophore models for differentiating P-glycoprotein substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Multispecificity of drug transporters: probing inhibitor selectivity for the human drug efflux transporters ABCB1 and ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Classification of substrates and inhibitors of P-glycoprotein using unsupervised machine learning approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Structure-activity relationship of P-glycoprotein substrates and modifiers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Classification analysis of P-glycoprotein substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Blood-brain barrier permeation models: discriminating between potential CNS and non-CNS drugs including P-glycoprotein substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Predicting P-glycoprotein substrates by a quantitative structure-activity relationship model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Prediction of P-glycoprotein substrates by a support vector machine approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Identifying P-glycoprotein substrates using a support vector machine optimized by a particle swarm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Structure of a bacterial multidrug ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Homology modeling of breast cancer resistance protein (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

SHED: Shannon Entropy Descriptors from Topological Feature Distributions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Ligand-based approach to in silico pharmacology: nuclear receptor profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

In silico pharmacology for drug discovery: applications to targets and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Global mapping of pharmacological space

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Relating protein pharmacology by ligand chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

P-glycoprotein recognition of substrates and circumvention through rational drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167

Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.4.9.1167