(Q60340345)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

title

Every step of the way: integrins in cancer progression and metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

Author Correction: Every step of the way: integrins in cancer progression and metastasis

10 April 2020

corrigendum / erratum

0 references

author

Hellyeh Hamidi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Johanna Ivaska

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

language of work or name

English

0 references

publication date

1 September 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

page(s)

533-548

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/s41568-018-0038-z

10 April 2020

exact match

0 references

cites work

Integrin ligands at a glance

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7 January 2021

Disintegrins from snake venoms and their applications in cancer research and therapy

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7 January 2021

Beyond RGD: virus interactions with integrins.

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7 January 2021

Integrin traffic - the update

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7 January 2021

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

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7 January 2021

The integrin adhesome network at a glance

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7 January 2021

Functional atlas of the integrin adhesome

1 reference

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7 January 2021

The integrin adhesome: from genes and proteins to human disease

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7 January 2021

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.

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7 January 2021

The complexity of integrins in cancer and new scopes for therapeutic targeting

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7 January 2021

Integrins as Therapeutic Targets: Successes and Cancers.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Endocytic Trafficking of Integrins in Cell Migration

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin inactivators: balancing cellular functions in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Reciprocal interactions between adhesion receptor signaling and MMP regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The hallmarks of CAFs in cancer invasion

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cancer-associated fibroblasts lead tumor invasion through integrin-β3-dependent fibronectin assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Emerging Biological Principles of Metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Intravascular Survival and Extravasation of Tumor Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin αvβ3 and fibronectin upregulate Slug in cancer cells to promote clot invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Signaling events mediated by α3β1 integrin are essential for mammary tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The opposing roles of laminin-binding integrins in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Characterization of integrin beta6 and thrombospondin-1 double-null mice

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Therapeutic targeting of integrin αvβ6 in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin alpha(v)beta6-associated ERK2 mediates MMP-9 secretion in colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Role of integrins in regulating proteases to mediate extracellular matrix remodeling

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

alpha5beta1-integrin expression is essential for tumor progression in experimental lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Binding of ZO-1 to α5β1 integrins regulates the mechanical properties of α5β1-fibronectin links

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin endosomal signalling suppresses anoikis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Ligand-independent activation of c-Met by fibronectin and α(5)β(1)-integrin regulates ovarian cancer invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tissue stiffness dictates development, homeostasis, and disease progression.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Src, p130Cas, and Mechanotransduction in Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin-mediated mechanotransduction

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

From transformation to metastasis: deconstructing the extracellular matrix in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tensional homeostasis and the malignant phenotype

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Role of YAP/TAZ in mechanotransduction

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

YAP regulates cell mechanics by controlling focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The role of integrins in TGFβ activation in the tumour stroma

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Lysyl oxidase expression in cardiac fibroblasts is regulated by α2β1 integrin interactions with the cellular microenvironment.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

On the move: endocytic trafficking in cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Traction dynamics of filopodia on compliant substrates.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cytoskeletal dynamics and nerve growth

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Collagen reorganization at the tumor-stromal interface facilitates local invasion

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Human pancreatic stellate cells modulate 3D collagen alignment to promote the migration of pancreatic ductal adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Association of collagen architecture with glioblastoma patient survival.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mena binds α5 integrin directly and modulates α5β1 function

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tensins: Bridging AMP-Activated Protein Kinase with Integrin Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

AMPK negatively regulates tensin-dependent integrin activity.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Desmoplasia suppression by metformin-mediated AMPK activation inhibits pancreatic cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Plasticity of Cell Migration In Vivo and In Silico.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Plasticity of Cancer Cell Invasion-Mechanisms and Implications for Therapy.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

EMT, the cytoskeleton, and cancer cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

E-cadherin-integrin crosstalk in cancer invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

New dimensions in cell migration

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Rho GTPase signalling in cell migration

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Persistent cell migration and adhesion rely on retrograde transport of β(1) integrin.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mutant p53 drives invasion by promoting integrin recycling

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Myosin-X provides a motor-based link between integrins and the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Filopodia in cell adhesion, 3D migration and cancer cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

FiloQuant reveals increased filopodia density during breast cancer progression.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Digging a little deeper: the stages of invadopodium formation and maturation

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Invadosome regulation by adhesion signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Invadosomes are coming: new insights into function and disease relevance

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrins: masters and slaves of endocytic transport.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Mechanistic insights into EGFR membrane clustering revealed by super-resolution imaging

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cell surface receptors for CCN proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The matricellular protein CYR61 promotes breast cancer lung metastasis by facilitating tumor cell extravasation and suppressing anoikis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Extracellular vesicles: biology and emerging therapeutic opportunities.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tumour exosome integrins determine organotropic metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Endothelial destabilization by angiopoietin-2 via integrin β1 activation.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Neuropilin-2 promotes extravasation and metastasis by interacting with endothelial α5 integrin

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Genes that mediate breast cancer metastasis to the brain

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A cell-ECM screening method to predict breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Knockdown of the β(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Visualizing extravasation dynamics of metastatic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cdc42 promotes transendothelial migration of cancer cells through β1 integrin

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Molecular characterization of circulating tumor cells in human metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Kindlin-1 promotes pulmonary breast cancer metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The role of formins in filopodia formation

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Epigenetics in breast cancer: what's new?

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Erlotinib resistance in lung cancer cells mediated by integrin β1/Src/Akt-driven bypass signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cilengitide induces autophagy-mediated cell death in glioma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

End of the road: confounding results of the CORE trial terminate the arduous journey of cilengitide for glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients withKRASwild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The ZNF304-integrin axis protects against anoikis in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

FAK signaling in human cancer as a target for therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK-AKT pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Lysyl oxidase in cancer inhibition and metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Matrix crosslinking forces tumor progression by enhancing integrin signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Molecular Pathways: Mucins and Drug Delivery in Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

MUC1 oncoprotein is a druggable target in human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Variation of Specific Activities of 68Ga-Aquibeprin and 68Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins α5β1 and αvβ3.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Complementary, Selective PET Imaging of Integrin Subtypes α5β1 and αvβ3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

In Vivo PET Imaging of the Cancer Integrin αvβ6 Using 68Ga-Labeled Cyclic RGD Nonapeptides

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The evolutionary history of lethal metastatic prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The final steps of integrin activation: the end game

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrins in angiogenesis and lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Immune checkpoint blockade: a common denominator approach to cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Inhibiting Metastasis and Preventing Tumor Relapse by Triggering Host Immunity with Tumor-Targeted Photodynamic Therapy Using Photosensitizer-Loaded Functional Nanographenes

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41568-018-0038-Z

7 January 2021

Neuropilin-2 expression affects the increased vascularization and is a prognostic factor in osteosarcoma

1 reference

12 December 2020

Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.

1 reference

12 December 2020

Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies.

1 reference

12 December 2020

Increased invasive potential and up-regulation of MMP-2 in MDA-MB-231 breast cancer cells expressing the beta3 integrin subunit

1 reference

12 December 2020

β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib

1 reference

12 December 2020

The primacy of β1 integrin activation in the metastatic cascade

1 reference

12 December 2020

β4 Integrin signaling induces expansion of prostate tumor progenitors

1 reference

12 December 2020

Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer

1 reference

12 December 2020

Corrigendum: Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.

1 reference

12 December 2020

Integrin α6/Akt/Erk signaling is essential for human breast cancer resistance to radiotherapy

1 reference

12 December 2020

10.1038/S41568-018-0038-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30002479%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

PubMed publication ID

30002479

1 reference