(Q60931282)

12 December 2020

The role of iron in cell cycle progression and the proliferation of neoplastic cells

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12 December 2020

Iron overload and its association with cancer risk in humans: evidence for iron as a carcinogenic metal

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12 December 2020

Iron metabolism and the IRE/IRP regulatory system: an update

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12 December 2020

Anti-tumor activities of four chelating agents against human neuroblastoma cells

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12 December 2020

Identification of the receptor scavenging hemopexin-heme complexes.

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12 December 2020

Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins

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12 December 2020

Modulation of iron transport proteins in human colorectal carcinogenesis

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12 December 2020

The transferrin receptor part II: targeted delivery of therapeutic agents into cancer cells

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12 December 2020

Tuning cell cycle regulation with an iron key.

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12 December 2020

Does excess iron play a role in breast carcinogenesis? An unresolved hypothesis

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12 December 2020

Iron increases MMP-9 expression through activation of AP-1 via ERK/Akt pathway in human head and neck squamous carcinoma cells

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12 December 2020

Iron-regulatory proteins: molecular biology and pathophysiological implications

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12 December 2020

Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox

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12 December 2020

Redox signaling and cancer: the role of "labile" iron

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12 December 2020

miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation

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12 December 2020

Scara5 is a ferritin receptor mediating non-transferrin iron delivery

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12 December 2020

miR-584 mediates post-transcriptional expression of lactoferrin receptor in Caco-2 cells and in mouse small intestine during the perinatal period

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12 December 2020

[Influence of magnetic Fe3O4 nanoparticle on functions of lymphocytes and macrophages in mice]

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12 December 2020

Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta.

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12 December 2020

The immunotherapeutic effect of Fe3O4 nanoparticles as adjuvants on mice H22 live cancer

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12 December 2020

Role of ferritin alterations in human breast cancer cells

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12 December 2020

Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells.

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12 December 2020

Two to tango: regulation of Mammalian iron metabolism

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12 December 2020

miR-214 regulates lactoferrin expression and pro-apoptotic function in mammary epithelial cells

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12 December 2020

The role of iron in tumour cell proliferation

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12 December 2020

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

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12 December 2020

Effects of DMSA-coated Fe3O4 magnetic nanoparticles on global gene expression of mouse macrophage RAW264.7 cells

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12 December 2020

An iron regulatory gene signature predicts outcome in breast cancer.

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12 December 2020

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

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12 December 2020

The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells

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12 December 2020

Novel chelators for cancer treatment: where are we now?

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12 December 2020

STEAP proteins: from structure to applications in cancer therapy.

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12 December 2020

The iron regulatory hormone hepcidin inhibits expression of iron release as well as iron uptake proteins in J774 cells.

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12 December 2020

Ferroptosis: an iron-dependent form of nonapoptotic cell death

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12 December 2020

Micromanaging Iron Homeostasis: hypoxia-inducible micro-RNA-210 suppresses iron homeostasis-related proteins

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12 December 2020

Gemcitabine and paclitaxel suppress the production of vascular endothelial growth factor induced by deferoxamine in human non-small cell lung cancer A549 cells

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12 December 2020

Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response

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12 December 2020

Kinetic analysis of iron-dependent histone demethylases: α-ketoglutarate substrate inhibition and potential relevance to the regulation of histone demethylation in cancer cells

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12 December 2020

Tumor-associated macrophages as potential diagnostic and prognostic biomarkers in breast cancer

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12 December 2020

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis.

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12 December 2020

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis

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12 December 2020

Efficacy and safety of deferasirox in myelodysplastic syndromes

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12 December 2020

Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin.

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12 December 2020

Iron and cancer: more ore to be mined

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12 December 2020

CD163 binding to haptoglobin-hemoglobin complexes involves a dual-point electrostatic receptor-ligand pairing

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12 December 2020

A mechanistic overview of TET-mediated 5-methylcytosine oxidation

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12 December 2020

The regulation of iron metabolism in the mononuclear phagocyte system.

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12 December 2020

Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism

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12 December 2020

Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species

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12 December 2020

De novo WDR45 mutation in a patient showing clinically Rett syndrome with childhood iron deposition in brain.

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12 December 2020

New signaling pathways for hepcidin regulation.

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12 December 2020

Synthesis of multifunctional Fe₃O₄-CdSe/ZnS nanoclusters coated with lipid A toward dendritic cell-based immunotherapy.

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12 December 2020

Lipopolysaccharides upregulate hepcidin in neuron via microglia and the IL-6/STAT3 signaling pathway

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12 December 2020

Ferritin heavy chain in triple negative breast cancer: a favorable prognostic marker that relates to a cluster of differentiation 8 positive (CD8+) effector T-cell response

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12 December 2020

Iron oxide nanoparticles induce oxidative stress, DNA damage, and caspase activation in the human breast cancer cell line.

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12 December 2020

MBD5 regulates iron metabolism via methylation-independent genomic targeting of Fth1 through KAT2A in mice.

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12 December 2020

SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1.

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12 December 2020

The IRP/IRE system in vivo: insights from mouse models

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12 December 2020

Connections between TET proteins and aberrant DNA modification in cancer

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12 December 2020

NDRG1 as a molecular target to inhibit the epithelial-mesenchymal transition: the case for developing inhibitors of metastasis

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12 December 2020

Epigenetic role for the conserved Fe-S cluster biogenesis protein AtDRE2 in Arabidopsis thaliana

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12 December 2020

A role for STEAP2 in prostate cancer progression

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12 December 2020

Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism.

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12 December 2020

Macrophage iron homeostasis and polarization in the context of cancer

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12 December 2020

Clinically approved iron chelators influence zebrafish mortality, hatching morphology and cardiac function

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12 December 2020

Disordered signaling governing ferroportin transcription favors breast cancer growth

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12 December 2020

Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities

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12 December 2020

Oxidative stress alters global histone modification and DNA methylation

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12 December 2020

Overexpression of JARID1B is associated with poor prognosis and chemotherapy resistance in epithelial ovarian cancer

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12 December 2020

Increased expression of HIF2α during iron deficiency-associated megakaryocytic differentiation

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12 December 2020

Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension

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12 December 2020

The mechanism of ageing: primary role of transposable elements in genome disintegration

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12 December 2020

Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation

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12 December 2020

β2-microglobulin induces epithelial-mesenchymal transition in human renal proximal tubule epithelial cells in vitro

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12 December 2020

DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma.

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12 December 2020

Targeting cancer by binding iron: Dissecting cellular signaling pathways

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12 December 2020

Iron homeostasis in host defence and inflammation

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12 December 2020

Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature.

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12 December 2020

An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis

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12 December 2020

HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation

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12 December 2020

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

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12 December 2020

miR-20a regulates expression of the iron exporter ferroportin in lung cancer

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12 December 2020

Decreased expression of ferroportin in prostate cancer

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12 December 2020

MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis

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12 December 2020

p53 genes function to restrain mobile elements

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12 December 2020

Local iron homeostasis in the breast ductal carcinoma microenvironment

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12 December 2020

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations.

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12 December 2020

Characterization of TNF-α- and IL-17A-Mediated Synergistic Induction of DEFB4 Gene Expression in Human Keratinocytes through IκBζ.

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12 December 2020

Iron participated in breast cancer chemoresistance by reinforcing IL-6 paracrine loop

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12 December 2020

Overview of Lactoferrin as a Natural Immune Modulator

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12 December 2020

Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases

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12 December 2020

Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases

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12 December 2020

EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1.

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12 December 2020

Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis

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12 December 2020

Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control

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12 December 2020

Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression

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12 December 2020

Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy

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12 December 2020

Multi-functional nanoparticles as theranostic agents for the treatment & imaging of pancreatic cancer

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12 December 2020

Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency

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12 December 2020

The iron chelator Dp44mT suppresses osteosarcoma's proliferation, invasion and migration: in vitro and in vivo

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12 December 2020

A Red Carpet for Iron Metabolism.

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12 December 2020

Deferasirox has strong anti-leukemia activity but may antagonize theanti-leukemia effect of doxorubicin

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12 December 2020

Targeting iron metabolism in drug discovery and delivery

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12 December 2020

Inhibition of prostate cancer proliferation by Deferiprone.

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12 December 2020

BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis

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12 December 2020

Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.

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12 December 2020

The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells

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12 December 2020

Targeting STEAP1 protein in human cancer: current trends and future challenges

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12 December 2020

Decreased Iron in Cancer Cells and Their Microenvironment Improves Cytolysis of Breast Cancer Cells by Natural Killer Cells

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12 December 2020

Molecular regulation of cellular iron balance.

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12 December 2020

HBV-specific CD4+ cytotoxic T cells in hepatocellular carcinoma are less cytolytic toward tumor cells and suppress CD8+ T cell-mediated antitumor immunity

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12 December 2020

IONP-doped nanoparticles for highly effective NIR-controlled drug release and combination tumor therapy

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12 December 2020

Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.

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12 December 2020

Gold-coated magnetic nanoparticle as a nanotheranostic agent for magnetic resonance imaging and photothermal therapy of cancer

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12 December 2020

Iron metabolism: State of the art.

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12 December 2020

G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin

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12 December 2020

The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes.

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12 December 2020

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

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12 December 2020

Dynamics of absorption, metabolism, and excretion of 5-aminolevulinic acid in human intestinal Caco-2 cells

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12 December 2020

JARID1 Histone Demethylases: Emerging Targets in Cancer

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12 December 2020

Iron suppresses ovarian granulosa cell proliferation and arrests cell cycle through regulating p38 mitogen-activated protein kinase/p53/p21 pathway

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12 December 2020

Ferritin iron regulators, PCBP1 and NCOA4, respond to cellular iron status in developing red cells

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12 December 2020

Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer

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12 December 2020

HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models.

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12 December 2020

Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis

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12 December 2020

Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth

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12 December 2020

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.

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12 December 2020

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

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12 December 2020

Ferrosenescence: The iron age of neurodegeneration?

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12 December 2020

Tuning the Distance of Rattle-Shaped IONP@Shell-in-Shell Nanoparticles for Magnetically-Targeted Photothermal Therapy in the Second Near-Infrared Window

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12 December 2020

Iron Oxide Nanoparticles: Innovative Tool in Cancer Diagnosis and Therapy.

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12 December 2020

A FTH1 gene:pseudogene:microRNA network regulates tumorigenesis in prostate cancer

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12 December 2020

Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells

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12 December 2020

Correlation between the concentrations of lactoferrin and neutrophil gelatinase-associated lipocalin in meconium

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12 December 2020

Potential role of NDRG2 in reprogramming cancer metabolism and epithelial -to-mesenchymal transition

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12 December 2020

Regulation of Transferrin Receptor-1 mRNA by the Interplay between IRE-binding proteins and miR-7/miR-141 in the 3'-IRE Stem-Loops.

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12 December 2020

A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese.

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12 December 2020

Emerging Strategies of Cancer Therapy Based on Ferroptosis.

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12 December 2020

The Role of Ferroptosis in Cancer Development and Treatment Response.

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12 December 2020

Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.

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12 December 2020

Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression.

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12 December 2020

Differential regulation of hepcidin in cancer and non-cancer tissues and its clinical implications.

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12 December 2020

Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages

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12 December 2020

Iron and Its Role in Cancer Defense: A Double-Edged Sword.

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12 December 2020

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.

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12 December 2020

Increased expression of hepcidin and associated upregulation of JAK/STAT3 signaling in human gastric cancer.

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12 December 2020

NEET proteins: A new link between iron metabolism, ROS and cancer.

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12 December 2020

MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker.

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12 December 2020

NDRG2 suppresses proliferation, migration, invasion and epithelial-mesenchymal transition of esophageal cancer cells through regulating the AKT/XIAP signaling pathway.

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12 December 2020

The theranostic efficiency of tumor-specific, pH-responsive, peptide-modified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles.

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12 December 2020

High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines.

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12 December 2020

Iron Oxide Nanoparticles-Based Vaccine Delivery for Cancer Treatment.

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12 December 2020

Ironing out the role of the cyclin-dependent kinase inhibitor, p21 in cancer: Novel iron chelating agents to target p21 expression and activity.

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12 December 2020

Superparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy.

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12 December 2020

Bevacizumab and near infrared probe conjugated iron oxide nanoparticles for vascular endothelial growth factor targeted MR and optical imaging

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12 December 2020

STEAP2 Knockdown Reduces the Invasive Potential of Prostate Cancer Cells.

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12 December 2020

Sustained Erythroid Response in a Patient with Myelofibrosis Receiving Concomitant Treatment with Ruxolitinib and Deferasirox

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12 December 2020

Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer.

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12 December 2020

Multivalent exposure of trastuzumab on iron oxide nanoparticles improves antitumor potential and reduces resistance in HER2-positive breast cancer cells.

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12 December 2020

Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion.

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12 December 2020

Myricetin-induced apoptosis of triple-negative breast cancer cells is mediated by the iron-dependent generation of reactive oxygen species from hydrogen peroxide.

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12 December 2020

Limitations of Serum Ferritin in Diagnosing Iron Deficiency in Inflammatory Conditions.

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12 December 2020

Nomograms incorporating genetic variants in BMP/Smad4/Hamp pathway to predict disease outcomes after definitive radiotherapy for non-small cell lung cancer.

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12 December 2020

Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism

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12 December 2020

Tumor associated macrophages deliver iron to tumor cells via Lcn2.

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12 December 2020

Cell iron status influences macrophage polarization.

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12 December 2020

TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation

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12 December 2020

Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer.

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12 December 2020

The tumor suppressor protein p53 and the ferroptosis network.

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12 December 2020

The iron chelator deferasirox synergises with chemotherapy to treat triple-negative breast cancers

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12 December 2020

Significance of serum ferritin as a prognostic factor in advanced hepatobiliary cancer patients treated with Korean medicine: a retrospective cohort study.

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12 December 2020

Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer

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12 December 2020

Iron(II)-Polypyridyl Complexes Inhibit the Growth of Glioblastoma Tumor and Enhance TRAIL-Induced Cell Apoptosis

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12 December 2020

The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin.

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12 December 2020

Deferasirox, an oral iron chelator, with gemcitabine synergistically inhibits pancreatic cancer cell growth in vitro and in vivo.

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12 December 2020

Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl-p53 pathway

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12 December 2020

Suppression of ferroportin expression by cadmium stimulates proliferation, EMT, and migration in triple-negative breast cancer cells

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12 December 2020

Blocking Autophagic Flux Enhances Iron Oxide Nanoparticle Photothermal Therapeutic Efficiency in Cancer Treatment

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12 December 2020

Iron-mediated oxidative cell death is a potential contributor to neuronal dysfunction induced by neonatal hemolytic hyperbilirubinemia

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12 December 2020

A promising new approach to cancer therapy: Targeting iron metabolism in cancer stem cells

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12 December 2020

Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases

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12 December 2020

Calcium is an essential cofactor for metal efflux by the ferroportin transporter family

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12 December 2020

Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor

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12 December 2020

NGAL promotes recruitment of tumor infiltrating leukocytes

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12 December 2020

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection

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12 December 2020

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12 December 2020

Magnetic delivery of Fe3O4@polydopamine nanoparticle-loaded natural killer cells suggest a promising anticancer treatment

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12 December 2020

Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation

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12 December 2020

Plasma ferritin concentration is positively associated with in vivo fatty acid mobilization and insulin resistance in obese women

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12 December 2020

Gold-coated iron oxide nanoparticles trigger apoptosis in the process of thermo-radiotherapy of U87-MG human glioma cells

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12 December 2020

The MYB/miR-130a/NDRG2 axis modulates tumor proliferation and metastatic potential in salivary adenoid cystic carcinoma

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12 December 2020

Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling

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12 December 2020

Role of GPX4 in ferroptosis and its pharmacological implication

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12 December 2020

Regulates Tumorigenesis and Chemoresistance During Peritoneal Metastasis of Gastric Cancer

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12 December 2020

E4BP4 promotes thyroid cancer proliferation by modulating iron homeostasis through repression of hepcidin

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12 December 2020

Anemia and Iron Deficiency in Cancer Patients: Role of Iron Replacement Therapy

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12 December 2020

Non-transferrin-bound iron transporters

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12 December 2020