(Q60954959)

1

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Mari Takalo

2

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Teemu Natunen

3

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Rebekka Wittrahm

4

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Sami Gabbouj

5

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Susanna Kemppainen

6

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Ville Leinonen

7

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Heikki Tanila

8

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Mikko Hiltunen

Frontiers in Neuroscience

10

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language of work or name

English

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publication date

2018

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published in

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volume

12

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page(s)

963

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copyright license

Creative Commons Attribution 4.0 International

start time

14 December 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Astrocyte glutamate transport: review of properties, regulation, and physiological functions

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12 December 2020

CD36 mediates the innate host response to beta-amyloid

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12 December 2020

Synaptic slaughter in Alzheimer's disease

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12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

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12 December 2020

Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action.

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12 December 2020

Using GOstats to test gene lists for GO term association

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12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

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12 December 2020

Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

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12 December 2020

The effects of aging, injury and disease on microglial function: a case for cellular senescence

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12 December 2020

Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogen-activated protein kinase cascades

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12 December 2020

Implication of Complement System and its Regulators in Alzheimer’s Disease

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12 December 2020

Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses.

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12 December 2020

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

1 reference

12 December 2020

Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors

1 reference

12 December 2020

Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease.

1 reference

12 December 2020

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

1 reference

12 December 2020

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

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12 December 2020

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

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12 December 2020

Amyloid-β as a modulator of synaptic plasticity

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12 December 2020

APP processing in Alzheimer's disease

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12 December 2020

Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors

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12 December 2020

Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis.

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12 December 2020

Synaptic pruning by microglia is necessary for normal brain development

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12 December 2020

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

1 reference

12 December 2020

NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD).

1 reference

12 December 2020

The complement system: an unexpected role in synaptic pruning during development and disease

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12 December 2020

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

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12 December 2020

Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice

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12 December 2020

Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony.

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12 December 2020

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

1 reference

12 December 2020

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

1 reference

12 December 2020

Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers.

1 reference

12 December 2020

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease

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12 December 2020

Cellular functions of the amyloid precursor protein from development to dementia

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12 December 2020

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

1 reference

12 December 2020

Immune attack: the role of inflammation in Alzheimer disease.

1 reference

12 December 2020

Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology

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12 December 2020

The Cellular Phase of Alzheimer's Disease

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12 December 2020

Complement and microglia mediate early synapse loss in Alzheimer mouse models.

1 reference

12 December 2020

Amyloid-β-Induced Dysregulation of AMPA Receptor Trafficking

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12 December 2020

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

1 reference

12 December 2020

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

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12 December 2020

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.

1 reference

12 December 2020

Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury

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12 December 2020

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.

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12 December 2020

Neurotoxic reactive astrocytes are induced by activated microglia

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12 December 2020

Triggering Receptor Expressed on Myeloid Cells 2, a Novel Regulator of Immunocyte Phenotypes, Confers Neuroprotection by Relieving Neuroinflammation.

1 reference

12 December 2020

Validating GWAS Variants from Microglial Genes Implicated in Alzheimer's Disease.

1 reference

12 December 2020

Decreased plasma β-amyloid in the Alzheimer's disease APP A673T variant carriers.

1 reference

12 December 2020

Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.

1 reference

12 December 2020

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

1 reference

12 December 2020

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

1 reference

12 December 2020

Physiological Concentrations of Amyloid Beta Regulate Recycling of Synaptic Vesicles via Alpha7 Acetylcholine Receptor and CDK5/Calcineurin Signaling

1 reference

12 December 2020

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

1 reference

12 December 2020

An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.

1 reference

12 December 2020

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

1 reference

12 December 2020

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy

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12 December 2020

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

1 reference

12 December 2020

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.

1 reference

12 December 2020

Normal aging induces A1-like astrocyte reactivity.

1 reference

12 December 2020

ApoE facilitates the microglial response to amyloid plaque pathology.

1 reference

12 December 2020

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.

1 reference

12 December 2020

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.

1 reference

12 December 2020

Microglial immune checkpoint mechanisms

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12 December 2020

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

1 reference

12 December 2020

A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer's disease

1 reference

12 December 2020

Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau.

1 reference

12 December 2020

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

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12 December 2020