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The identity and function of microglia in neurodegeneration
scientific article published on 24 September 2018
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
title
The identity and function of microglia in neurodegeneration
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
main subject
microglia
0 references
neurodegeneration
1 reference
based on heuristic
inferred from title
author
Marco Colonna
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
author name string
Wilbur M Song
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
language of work or name
English
0 references
publication date
24 September 2018
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
published in
Nature Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
volume
19
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
issue
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
page(s)
1048-1058
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
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Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
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Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease
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Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ
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Metabolic regulation of brain Abeta by neprilysin.
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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation
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TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.
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IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice
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Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition
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Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
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based on heuristic
inferred from DOI database lookup
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gamma frequency entrainment attenuates amyloid load and modifies microglia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the Inflammasome Sensor Aim2 Mitigates Aβ Deposition and Microglial Activation but Increases Inflammatory Cytokine Expression in an Alzheimer Disease Mouse Model.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inefficient clearance of myelin debris by microglia impairs remyelinating processes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TREM2 regulates microglial cell activation in response to demyelination in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The classical complement cascade mediates CNS synapse elimination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of the microglial receptor CX3CR1 impairs postnatal functional development of thalamocortical synapses in the barrel cortex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A complement-microglial axis drives synapse loss during virus-induced memory impairment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retracted article: Microglia-dependent synapse loss in type I interferon-mediated lupus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
USP18 lack in microglia causes destructive interferonopathy of the mouse brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAM receptors regulate multiple features of microglial physiology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in NRROS show abnormal microglial development and neurological disorders.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxic reactive astrocytes are induced by activated microglia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired differentiation of osteoclasts in TREM-2-deficient individuals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristic microglial features in patients with hereditary diffuse leukoencephalopathy with spheroids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TREM2 Variants in Alzheimer's Disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coding variants in TREM2 increase risk for Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TYROBP genetic variants in early-onset Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Onset and progression in inherited ALS determined by motor neurons and microglia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C9orf72 nucleotide repeat structures initiate molecular cascades of disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C9orf72 is required for proper macrophage and microglial function in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-synuclein and neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease: from molecular pathogenesis to clinical treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An environment-dependent transcriptional network specifies human microglia identity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptomic atlas of aged human microglia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human side of microglia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41590-018-0212-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/S41590-018-0212-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
PubMed publication ID
30250185
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30250185
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250185%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 April 2020
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