(Q62071833)

12 December 2020

Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide

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12 December 2020

Reaction of chromium (VI) with hydrogen peroxide in the presence of glutathione: reactive intermediates and resulting DNA damage

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12 December 2020

Why is the hydroxyl radical the only radical that commonly adds to DNA? Hypothesis: it has a rare combination of high electrophilicity, high thermochemical reactivity, and a mode of production that can occur near DNA.

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12 December 2020

Diurnal variations of benzodiazepine binding in rat cerebral cortex: disruption by pinealectomy

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12 December 2020

Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man

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12 December 2020

Circannual reproductive rhythms in mammals related to photoperiod and pineal function: a review

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12 December 2020

Melatonin stimulates brain glutathione peroxidase activity.

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12 December 2020

Is copper pro- or anti-inflammatory? A reconciling view and a novel approach for the use of copper in the control of inflammation

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12 December 2020

Antioxidant activity of melatonin in mice.

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12 December 2020

The melatonin rhythm: both a clock and a calendar

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12 December 2020

The reaction of no with superoxide

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12 December 2020

Instability and decay of the primary structure of DNA

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12 December 2020

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

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12 December 2020

Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks

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12 December 2020

Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry.

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12 December 2020

Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes

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12 December 2020

Reaction of Melatonin and Related Indoles With Hydroxyl Radicals: EPR and Spin Trapping Investigations

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12 December 2020

Melatonin protects bovine cerebral endothelial cells from hyperoxia-induced DNA damage and death

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12 December 2020

Premature oxidative aging of hepatic mitochondrial DNA in Wilson's disease

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12 December 2020

Melatonin and a spin-trap compound block radiofrequency electromagnetic radiation-induced DNA strand breaks in rat brain cells

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12 December 2020

Melatonin and vitamin E limit nitric oxide-induced lipid peroxidation in rat brain homogenates.

1 reference

12 December 2020

Effect of melatonin and metabolites on copper-mediated oxidation of flow density lipoprotein

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12 December 2020

Free radical-induced tandem base damage in DNA oligomers

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12 December 2020

Copper(II) interactions with nonsteroidal antiinflammatory agents. II. Anthranilic acid as a potential. OH-inactivating ligand.

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12 December 2020

Safety of melatonin in long-term use (?)

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12 December 2020

The amyloid beta protein induces oxidative damage of mitochondrial DNA.

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12 December 2020

The interaction of melatonin and its precursors with aluminium, cadmium, copper, iron, lead, and zinc: an adsorptive voltammetric study

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12 December 2020

DNA damage induced via independent generation of the radical resulting from formal hydrogen atom abstraction from the C1'-position of a nucleotide

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12 December 2020

Melatonin as a hydroxyl radical scavenger.

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12 December 2020

DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone

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12 December 2020

A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation

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12 December 2020

Ultrastructural confirmation of neuronal protection by melatonin against the neurotoxin 6-hydroxydopamine cell damage

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12 December 2020

Melatonin and protection from whole-body irradiation: survival studies in mice

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12 December 2020

Identification of the factors affecting the rate of deactivation of hypochlorous acid by melatonin

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12 December 2020

Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain

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12 December 2020

The pineal secretory product melatonin reduces hydrogen peroxide-induced DNA damage in U-937 cells

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12 December 2020

DNA Damage in Deoxynucleosides and Oligonucleotides Treated with Peroxynitrite

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12 December 2020

The effect of melatonin on lipid peroxidation during radiotherapy in female rats

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12 December 2020

Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3

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12 December 2020

Structure-activity relationships in a series of melatonin analogues with the low-density lipoprotein oxidation model

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12 December 2020

Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats

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12 December 2020

Melatonin protects against age-related DNA damage in the brains of female senescence-accelerated mice

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12 December 2020

Melatonin and protection from genetic damage in blood and bone marrow: whole-body irradiation studies in mice

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12 December 2020

Alzheimer beta protein mediated oxidative damage of mitochondrial DNA: prevention by melatonin

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12 December 2020

Oxidants and antioxidants in atherogenesis. An appraisal

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12 December 2020

Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney

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12 December 2020

N-acetylserotonin, melatonin and their derivatives improve cognition and protect against beta-amyloid-induced neurotoxicity.

1 reference

12 December 2020

High levels of 8-hydroxy-2'-deoxyguanosine appear in normal human epidermis after a single dose of ultraviolet radiation

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12 December 2020

Reaction of HO* with guanine derivatives in aqueous solution: formation of two different redox-active OH-adduct radicals and their unimolecular transformation reactions. Properties of G(-H)*

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12 December 2020

Copper--ligand interactions and the physiological free radical processes. Part 3. Influence of histidine, salicylic acid and anthranilic acid on copper-driven Fenton chemistry in vitro

1 reference

12 December 2020

Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells

1 reference

12 December 2020

Chromium(III)-induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants: comparative effects of melatonin, ascorbate, and vitamin E.

1 reference

12 December 2020

Nitrite-induced deamination and hypochlorite-induced oxidation of DNA in intact human respiratory tract epithelial cells

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12 December 2020

Significance of melatonin in antioxidative defense system: reactions and products

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12 December 2020

Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means

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12 December 2020

Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules.

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12 December 2020

Melatonin reduces the oxidation of nuclear DNA and membrane lipids induced by the carcinogen delta-aminolevulinic acid

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12 December 2020

Protective effect of melatonin on methylmercury-Induced mortality in mice

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12 December 2020

Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation

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12 December 2020

Actions of melatonin in the reduction of oxidative stress. A review

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12 December 2020

Myeloperoxidase-catalyzed oxidation of melatonin by activated neutrophils

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12 December 2020

Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation

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12 December 2020

Comparison of the protective effect of melatonin with other antioxidants in the hamster kidney model of estradiol-induced DNA damage.

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12 December 2020

Antioxidants in health and disease.

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12 December 2020

Melatonin prevents delta-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+.

1 reference

12 December 2020

DNA oxidatively damaged by chromium(III) and H(2)O(2) is protected by the antioxidants melatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine, resveratrol and uric acid

1 reference

12 December 2020

Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model

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12 December 2020

Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice

1 reference

12 December 2020

Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models

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12 December 2020

Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system

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12 December 2020

Protective effect of melatonin on naphthalene-induced oxidative stress and DNA damage in cultured macrophage J774A.1 cells

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12 December 2020

N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.

1 reference

12 December 2020

Protective effect of melatonin against in vitro iron ions and 7 mT 50 Hz magnetic field-induced DNA damage in rat lymphocytes

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12 December 2020

N-acetylserotonin suppresses hepatic microsomal membrane rigidity associated with lipid peroxidation

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12 December 2020

Preventive effect of melatonin against DNA damage induced by cyanide, kainate, glutathione/Fe(3+)/O(2), or H(2)O(2)/Fe(2+).

1 reference

12 December 2020

Protective effect of vitamin E against mercuric chloride reproductive toxicity in male mice

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12 December 2020

Free radicals in the physiological control of cell function

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12 December 2020

Melatonin reduces phosphine-induced lipid and DNA oxidation in vitro and in vivo in rat brain

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12 December 2020

Oxidative Strand Scission of Nucleic Acids: Routes Initiated by Hydrogen Abstraction from the Sugar Moiety

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12 December 2020

Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid

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12 December 2020

Autoxidation and toxicant-induced oxidation of lipid and DNA in monkey liver: reduction of molecular damage by melatonin

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12 December 2020

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

1 reference

12 December 2020

Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurement in gamma-irradiated isolated DNA.

1 reference

12 December 2020

Melatonin protects against copper-mediated free radical damage

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12 December 2020

The identification of the UV degradants of melatonin and their ability to scavenge free radicals

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12 December 2020

Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis

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12 December 2020

Melatonin as an effective protector against doxorubicin-induced cardiotoxicity

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12 December 2020

Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome

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12 December 2020

DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way.

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12 December 2020

Apoptotic molecules and MPTP-induced cell death

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12 December 2020

Melatonin attenuates brain mitochondria DNA damage induced by potassium cyanide in vivo and in vitro

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12 December 2020

Melatonin: reducing the toxicity and increasing the efficacy of drugs

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12 December 2020

Oxidation of melatonin by carbonate radicals and chemiluminescence emitted during pyrrole ring cleavage

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12 December 2020

Further insights into the reaction of melatonin with hydroxyl radical

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12 December 2020

6-Hydroxymelatonin converts Fe (III) to Fe (II) and reduces iron-induced lipid peroxidation

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12 December 2020

Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected.

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12 December 2020

Melatonin prevents the increase in hydroxyl radical-spin trap adduct formation caused by the addition of cisplatin in vitro

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12 December 2020

Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice

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12 December 2020

Protection against oxidative protein damage induced by metal-catalyzed reaction or alkylperoxyl radicals: comparative effects of melatonin and other antioxidants

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12 December 2020

Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.

1 reference

12 December 2020

Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions

1 reference

12 December 2020

In Vivo and in Vitro Effects of Melatonin or Ganglioside GT1B on L-Cysteine-Induced Brain Mitochondrial DNA Damage in Mice

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12 December 2020

Oxidative DNA damage: mechanisms, mutation, and disease

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12 December 2020

Melatonin prevents free radical formation due to the interaction between beta-amyloid peptides and metal ions [Al(III), Zn(II), Cu(II), Mn(II), Fe(II)].

1 reference

12 December 2020

Oxidation of melatonin by singlet molecular oxygen (O2(1deltag)) produces N1-acetyl-N2-formyl-5-methoxykynurenine

1 reference

12 December 2020

Extracellular mitochondrial DNA and oxidatively damaged DNA in synovial fluid of patients with rheumatoid arthritis

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12 December 2020

Melatonin: structural characterization of its non-enzymatic mono-oxygenate metabolite

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12 December 2020

Independent Generation of 5-(2‘-Deoxycytidinyl)methyl Radical and the Formation of a Novel Cross-Link Lesion between 5-Methylcytosine and Guanine

1 reference

12 December 2020

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction

1 reference

12 December 2020

6-Hydroxymelatonin protects against cyanide induced oxidative stress in rat brain homogenates

1 reference

12 December 2020

Mechanism of arsenic carcinogenesis: an integrated approach

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12 December 2020

Interaction of singlet molecular oxygen with melatonin and related indoles

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12 December 2020

Melatonin protects against mercury(II)-induced oxidative tissue damage in rats

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12 December 2020

Reactive nitrogen species in the chemical biology of inflammation

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12 December 2020

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12 December 2020

Hypochlorous acid-induced oxidative stress in Chinese hamster B14 cells: viability, DNA and protein damage and the protective action of melatonin.

1 reference

12 December 2020

Protective effects of melatonin on the ionizing radiation induced DNA damage in the rat brain

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12 December 2020

Effects of melatonin on the nitric oxide treated retina.

1 reference

12 December 2020

Oxidative DNA damage and disease: induction, repair and significance

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12 December 2020

Endogenous formation of novel halogenated 2'-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation

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12 December 2020

Antioxidants and prevention of chronic disease

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12 December 2020

Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: mechanistic studies with 18O.

1 reference

12 December 2020

Photocatalytic actions of the pesticide metabolite 2-hydroxyquinoxaline: destruction of antioxidant vitamins and biogenic amines - implications of organic redox cycling

1 reference

12 December 2020

Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.

1 reference

12 December 2020

Oxidative DNA injury after experimental intracerebral hemorrhage.

1 reference

12 December 2020

XRCC1 is required for DNA single-strand break repair in human cells

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12 December 2020

Metals, toxicity and oxidative stress

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12 December 2020

6-Hydroxymelatonin protects against quinolinic-acid-induced oxidative neurotoxicity in the rat hippocampus.

1 reference

12 December 2020

Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro

1 reference

12 December 2020

A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes.

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12 December 2020

Occupational exposure to mercury vapour on genotoxicity and DNA repair

1 reference

12 December 2020

Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK.

1 reference

12 December 2020

Antioxidative Protection by Melatonin: Multiplicity of Mechanisms from Radical Detoxification to Radical Avoidance

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12 December 2020

A Review of the Multiple Actions of Melatonin on the Immune System

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12 December 2020

Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation.

1 reference

12 December 2020

Melatonin and 6-hydroxymelatonin protect against iron-induced neurotoxicity

1 reference

12 December 2020

Quantitation of four guanine oxidation products from reaction of DNA with varying doses of peroxynitrite

1 reference

12 December 2020

Free radicals, metals and antioxidants in oxidative stress-induced cancer

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12 December 2020

Melatonin directly scavenges free radicals generated in red blood cells and a cell-free system: chemiluminescence measurements and theoretical calculations

1 reference

12 December 2020

Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems

1 reference

12 December 2020

Elevated levels of oxidative DNA damage in serum and myocardium of patients with heart failure

1 reference

12 December 2020

Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin

1 reference

12 December 2020

Free radicals and antioxidants in normal physiological functions and human disease

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12 December 2020

Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones

1 reference

12 December 2020

DNA oxidation in Alzheimer's disease

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12 December 2020

Investigation of the in vitro antioxidant behaviour of some 2-phenylindole derivatives: discussion on possible antioxidant mechanisms and comparison with melatonin

1 reference

12 December 2020

Microcystin-induced 8-hydroxydeoxyguanosine in DNA and its reduction by melatonin, vitamin C, and vitamin E in mice

1 reference

12 December 2020

Increased DNA damage and oxidative stress in patients with rheumatoid arthritis

1 reference

12 December 2020

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?

1 reference

12 December 2020

Nitric oxide and peroxynitrite in health and disease

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12 December 2020

AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice.

1 reference

12 December 2020

UVB-Induced formation of intrastrand cross-link products of DNA in MCF-7 cells treated with 5-bromo-2'-deoxyuridine

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12 December 2020

Oxyl radicals, redox-sensitive signalling cascades and antioxidants

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12 December 2020

N(1)-acetyl-5-methoxykynuramine contrasts with other tryptophan metabolites by a peculiar type of NO scavenging: cyclization to a cinnolinone prevents formation of unstable nitrosamines

1 reference

12 December 2020

Protective action of melatonin against oxidative DNA damage: chemical inactivation versus base-excision repair

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12 December 2020

Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia

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12 December 2020

Reactions of the NO redox forms NO+, *NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine

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12 December 2020

Biochemistry of oxidative stress

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12 December 2020

Association between oxidative DNA damage and telomere shortening in circulating endothelial progenitor cells obtained from metabolic syndrome patients with coronary artery disease

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12 December 2020

The chemical toxicology of 2-deoxyribose oxidation in DNA.

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12 December 2020

Melatonin, endocrine pancreas and diabetes.

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12 December 2020

Oxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines

1 reference

12 December 2020

Medical implications of melatonin: receptor-mediated and receptor-independent actions

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12 December 2020

DNA adducts with lipid peroxidation products

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12 December 2020

Lipid, protein, DNA oxidation and antioxidant status in rheumatoid arthritis

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12 December 2020

Increased mitochondrial oxidative damage and oxidative DNA damage contributes to the neurodegenerative process in sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

Melatonin preserves fetal growth in rats by protecting against ischemia/reperfusion-induced oxidative/nitrosative mitochondrial damage in the placenta

1 reference

12 December 2020

Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

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12 December 2020

Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.

1 reference

12 December 2020

Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK.

1 reference

12 December 2020

Peroxynitrite damages U937 cell DNA via the intermediate formation of mitochondrial oxidants

1 reference

12 December 2020

Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

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12 December 2020

The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger

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12 December 2020

Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells

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12 December 2020

Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects

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12 December 2020

Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes

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12 December 2020

Examination of hypochlorous acid-induced damage to cytosine residues in a CpG dinucleotide in DNA.

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12 December 2020

Melatonin analogue new indole hydrazide/hydrazone derivatives with antioxidant behavior: synthesis and structure-activity relationships

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12 December 2020

A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration

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12 December 2020

Melatonin: Quantum-chemical and biochemical investigation of antioxidant activity

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12 December 2020

A reevaluation of the ambident reactivity of the guanine moiety towards hydroxyl radicals

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12 December 2020

Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal

1 reference

12 December 2020

8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis

1 reference

12 December 2020

Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice.

1 reference

12 December 2020

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

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12 December 2020

Formation of spiroiminodihydantoin nucleoside from 8-oxo-7,8-dihydro-2'-deoxyguanosine by nitric oxide under aerobic conditions

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12 December 2020

Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the CSF of patients with Alzheimer's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process

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12 December 2020

Endogenous melatonin and oxidatively damaged guanine in DNA

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12 December 2020

Guanosine + OH radical reaction in aqueous solution: a reinterpretation of the UV-vis data based on thermodynamic and kinetic calculations.

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12 December 2020

Reactions of the melatonin metabolite N(1)-acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds

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12 December 2020

Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes

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12 December 2020

Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the cerebrospinal fluid of patients with living Parkinson's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurod

1 reference

12 December 2020

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness

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12 December 2020

Oxidation reactions of cytosine DNA components by hydroxyl radical and one-electron oxidants in aerated aqueous solutions

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12 December 2020

Chemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation

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12 December 2020

Melatonin as a potential tool against oxidative damage and apoptosis in ejaculated human spermatozoa.

1 reference

12 December 2020

Melatonin treatment normalizes plasma pro-inflammatory cytokines and nitrosative/oxidative stress in patients suffering from Duchenne muscular dystrophy

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12 December 2020

Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats

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12 December 2020

Novel indole-based analogs of melatonin: synthesis and in vitro antioxidant activity studies.

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12 December 2020

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

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12 December 2020

Effect of melatonin on the expression of Nrf2 and NF-kappaB during cyclophosphamide-induced urinary bladder injury in rat.

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12 December 2020

Melatonin: a multitasking molecule

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12 December 2020

Melatonin enhances antioxidant action of alpha-tocopherol and ascorbate against NADPH- and iron-dependent lipid peroxidation in human placental mitochondria

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12 December 2020

Oxidation of melatonin by taurine chloramine.

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12 December 2020

Protective effect of melatonin against Opisthorchis viverrini-induced oxidative and nitrosative DNA damage and liver injury in hamsters

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12 December 2020

Evaluation of in vitro anti-genotoxic potential of melatonin against arsenic and fluoride in human blood cultures

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12 December 2020

Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF‐κB and Nrf2 cascades

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12 December 2020

Role of oxidative stress and DNA damage in human carcinogenesis

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12 December 2020

Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro

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12 December 2020

Neurotoxins: free radical mechanisms and melatonin protection

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12 December 2020

Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates

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12 December 2020

Melatonin protects human cells from clustered DNA damages, killing and acquisition of soft agar growth induced by X-rays or 970 MeV/n Fe ions

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12 December 2020

On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals

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12 December 2020

Characterization of 2'-deoxyguanosine oxidation products observed in the Fenton-like system Cu(II)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts

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12 December 2020

Oxidative damage DNA: 8-oxoGua and 8-oxodG as molecular markers of cancer

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12 December 2020

Oxidative lipid, protein, and DNA damage as oxidative stress markers in vascular complications of diabetes mellitus

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12 December 2020

Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives

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12 December 2020

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

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12 December 2020

Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin

1 reference

12 December 2020

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics

1 reference

12 December 2020

Synthesis and comparison of antioxidant properties of indole-based melatonin analogue indole amino Acid derivatives

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12 December 2020

Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation.

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12 December 2020

Effect of melatonin administration on DNA damage and repair responses in lymphocytes of rats subchronically exposed to lead

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12 December 2020

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

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12 December 2020

Mechanisms of free radical-induced damage to DNA.

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12 December 2020

Association between DNA strand breakage and oxidative, inflammatory and endothelial biomarkers in type 2 diabetes.

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12 December 2020

Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy

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12 December 2020

Oxidative and non-oxidative DNA damage and cardiovascular disease.

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12 December 2020

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model.

1 reference

12 December 2020

Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis

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12 December 2020

Effects of hypoxia on epididymal sperm parameters and protective role of ibuprofen and melatonin

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12 December 2020

On the evolution of one-electron-oxidized deoxyguanosine in damaged DNA under physiological conditions: a DFT and ONIOM study on proton transfer and equilibrium

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12 December 2020

On the Chemical Repair of DNA Radicals by Glutathione: Hydrogen vs Electron Transfer

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12 December 2020

Melatonin-rich transgenic rice plants exhibit resistance to herbicide-induced oxidative stress

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12 December 2020

Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin

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12 December 2020

Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease

1 reference

12 December 2020

Melatonin and synthetic analogs as antioxidants

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12 December 2020

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK.

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12 December 2020

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

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12 December 2020

Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen, and γ-radiation

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12 December 2020

The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives

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12 December 2020

DNA damage due to oxidative stress in Chronic Obstructive Pulmonary Disease (COPD)

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12 December 2020

Role of melatonin and its receptors in the vertebrate retina

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12 December 2020

Melatonin enhances DNA repair capacity possibly by affecting genes involved in DNA damage responsive pathways

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12 December 2020

Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

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12 December 2020

Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats.

1 reference

12 December 2020

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

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12 December 2020

Effects of melatonin on DNA damage induced by cyclophosphamide in rats

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12 December 2020

Melatonin reduces oxidative stress in the erythrocytes of multiple sclerosis patients with secondary progressive clinical course

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12 December 2020

Melatonin protects rat thymus against oxidative stress caused by exposure to microwaves and modulates proliferation/apoptosis of thymocytes.

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12 December 2020

Peripheral reproductive organ health and melatonin: ready for prime time

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12 December 2020

Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis

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12 December 2020

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.

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12 December 2020

Free radicals, antioxidants in disease and health

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12 December 2020

Therapeutic approaches of melatonin in microwave radiations-induced oxidative stress-mediated toxicity on male fertility pattern of Wistar rats

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12 December 2020

Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease

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12 December 2020

Oxidative stress, DNA damage and repair in heart failure patients after implantation of continuous flow left ventricular assist devices

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12 December 2020

Melatonin attenuates phenytoin sodium-induced DNA damage

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12 December 2020

Mitigative role of melatonin and α-tocopherol against mercury-induced genotoxicity.

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12 December 2020

Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions

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12 December 2020

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

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12 December 2020

Selective protection of the cerebellum against intracerebroventricular LPS is mediated by local melatonin synthesis

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12 December 2020

N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.

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12 December 2020

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

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12 December 2020

A review of metal-catalyzed molecular damage: protection by melatonin

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12 December 2020

The potential ameliorative effects of melatonin against cyclophosphamide-induced DNA damage in murine bone marrow cells

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12 December 2020

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2-ARE signaling pathway as a potential mechanism

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12 December 2020

Generation of guanine-amino acid cross-links by a free radical combination mechanism

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12 December 2020

Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.

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12 December 2020

The prevention of ischemia/reperfusion induced oxidative damage by venous blood in rabbit kidneys monitored with biochemical, histopatological and immunohistochemical analysis

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12 December 2020

N-acetyl-serotonin protects HepG2 cells from oxidative stress injury induced by hydrogen peroxide

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12 December 2020

Essential actions of melatonin in protecting the ovary from oxidative damage

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12 December 2020

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.

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12 December 2020

Melatonin: exceeding expectations

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12 December 2020

Exogenous melatonin supplementation prevents oxidative stress-evoked DNA damage in human spermatozoa.

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12 December 2020

A review of melatonin as a suitable antioxidant against myocardial ischemia-reperfusion injury and clinical heart diseases.

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12 December 2020

Local melatoninergic system as the protector of skin integrity

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12 December 2020

Melatonin antagonizes Mn-induced oxidative injury through the activation of keap1-Nrf2-ARE signaling pathway in the striatum of mice

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12 December 2020

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

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12 December 2020

Melatonin, its metabolites and its synthetic analogs as multi-faceted compounds: antioxidant, prooxidant and inhibitor of bioactivation reactions

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12 December 2020

Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis.

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12 December 2020

Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer

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12 December 2020

The effect of melatonin on the liver of rats exposed to microwave radiation.

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12 December 2020

Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line

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12 December 2020

N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin

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12 December 2020

Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells.

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12 December 2020

Melatonin: an ancient molecule that makes oxygen metabolically tolerable.

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12 December 2020

Comprehensive Assessment of Oxidatively Induced Modifications of DNA in a Rat Model of Human Wilson's Disease

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12 December 2020

The Effects of Melatonin on Oxidative Stress Parameters and DNA Fragmentation in Testicular Tissue of Rats Exposed to Microwave Radiation.

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12 December 2020

Oxidative DNA damage is associated with inflammatory response, insulin resistance and microvascular complications in type 2 diabetes.

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12 December 2020

The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial

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12 December 2020

The Safety of Melatonin in Humans

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12 December 2020

Elevated Levels of Urinary Markers of Oxidative DNA and RNA Damage in Type 2 Diabetes with Complications

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12 December 2020

Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.

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12 December 2020

Melatonin pretreatment enhances the therapeutic effects of exogenous mitochondria against hepatic ischemia-reperfusion injury in rats through suppression of mitochondrial permeability transition

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12 December 2020

DNA Damage and Oxidative DNA Damage in Inflammatory Bowel Disease

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12 December 2020

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviol

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12 December 2020

Melatonin promotes blood-brain barrier integrity in methamphetamine-induced inflammation in primary rat brain microvascular endothelial cells

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12 December 2020

WITHDRAWN: Melatonin improves methamphetamine-induced blood brain barrier impairment through NADPH oxidase-2 in primary rat brain microvascular endothelium cells

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12 December 2020

Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte's Quality under in Vitro Conditions.

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12 December 2020

What causes human cancer? Approaches from the chemistry of DNA damage

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12 December 2020

Melatonin as an antioxidant: under promises but over delivers

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12 December 2020

Effect and possible mechanisms of melatonin treatment on the quality and developmental potential of aged bovine oocytes

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12 December 2020

Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress

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12 December 2020

Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases.

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12 December 2020

Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage

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12 December 2020

Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells

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12 December 2020

Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways.

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12 December 2020

Expression Levels of Two DNA Repair-related Genes under 8 Gy Ionizing Radiation and 100 Mg/Kg Melatonin Delivery In Rat Peripheral Blood

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12 December 2020

Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways

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12 December 2020

Melatonin treatment enhances therapeutic effects of exosomes against acute liver ischemia-reperfusion injury

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12 December 2020

Melatonin successfully rescues hippocampal bioenergetics and improves cognitive function following drug intoxication by promoting Nrf2-ARE signaling activity.

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12 December 2020

The anti-inflammatory and antioxidant effects of melatonin on LPS-stimulated bovine mammary epithelial cells

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12 December 2020

Melatonin Role in Ameliorating Radiation-induced Skin Damage: From Theory to Practice (A Review of Literature).

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12 December 2020

Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues

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12 December 2020

Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.

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12 December 2020

Melatonin counteracts cobalt nanoparticle‑induced cytotoxicity and genotoxicity by deactivating reactive oxygen species‑dependent mechanisms in the NRK cell line

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12 December 2020

Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.

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12 December 2020

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

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12 December 2020

Melatonin enhances the developmental competence of porcine somatic cell nuclear transfer embryos by preventing DNA damage induced by oxidative stress.

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12 December 2020

Nrf2/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammation.

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12 December 2020

DNA versus RNA oxidation in Parkinson's disease: Which is more important?

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12 December 2020

Not breathing is not an option: How to deal with oxidative DNA damage

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12 December 2020

Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children With Autism Spectrum Disorder

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12 December 2020

Effect of Melatonin Supplementation on Antioxidant Status and DNA Damage in High Intensity Trained Athletes.

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12 December 2020

Melatonin mitigates thioacetamide-induced hepatic fibrosis via antioxidant activity and modulation of proinflammatory cytokines and fibrogenic genes

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12 December 2020

Modulation of Radiation-induced Base Excision Repair Pathway Gene Expression by Melatonin.

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12 December 2020