(Q64864804)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

The effect of truncation on prion-like properties of α-synuclein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

author name string

Makoto Terada

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Genjiro Suzuki

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Takashi Nonaka

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Fuyuki Kametani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Akira Tamaoka

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Masato Hasegawa

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

language of work or name

English

0 references

publication date

20 July 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

13 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

volume

293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

page(s)

13910-13920

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6130941/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Identification of two distinct synucleins from human brain

1 reference

12 December 2020

Alpha-synuclein in Lewy bodies

1 reference

12 December 2020

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1 reference

12 December 2020

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

1 reference

12 December 2020

Synthetic filaments assembled from C-terminally truncated alpha-synuclein

1 reference

12 December 2020

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

1 reference

12 December 2020

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

1 reference

12 December 2020

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

1 reference

12 December 2020

Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human alpha-synuclein

1 reference

12 December 2020

Residual structure and dynamics in Parkinson's disease-associated mutants of alpha-synuclein

1 reference

12 December 2020

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

12 December 2020

Biochemical characterization of the core structure of alpha-synuclein filaments

1 reference

12 December 2020

An alternatively spliced form of rodent alpha-synuclein forms intracellular inclusions in vitro: role of the carboxy-terminus in alpha-synuclein aggregation

1 reference

12 December 2020

Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells

1 reference

12 December 2020

Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions

1 reference

12 December 2020

The N-terminal repeat domain of alpha-synuclein inhibits beta-sheet and amyloid fibril formation

1 reference

12 December 2020

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro

1 reference

12 December 2020

Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies

1 reference

12 December 2020

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

1 reference

12 December 2020

Protein aggregation and neurodegenerative disease

1 reference

12 December 2020

Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro

1 reference

12 December 2020

Ubiquitination of alpha-synuclein.

1 reference

12 December 2020

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

1 reference

12 December 2020

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

12 December 2020

A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

1 reference

12 December 2020

Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases

1 reference

12 December 2020

Cysteine misincorporation in bacterially expressed human alpha-synuclein

1 reference

12 December 2020

Small molecule inhibitors of alpha-synuclein filament assembly

1 reference

12 December 2020

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.

1 reference

12 December 2020

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

1 reference

12 December 2020

The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states

1 reference

12 December 2020

The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease

1 reference

12 December 2020

Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein

1 reference

12 December 2020

Role of different regions of alpha-synuclein in the assembly of fibrils.

1 reference

12 December 2020

Impact of Tyr to Ala mutations on alpha-synuclein fibrillation and structural properties

1 reference

12 December 2020

Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species

1 reference

12 December 2020

Conversion of wild-type alpha-synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant.

1 reference

12 December 2020

E46K Parkinson's-linked mutation enhances C-terminal-to-N-terminal contacts in alpha-synuclein

1 reference

12 December 2020

Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

1 reference

12 December 2020

Prion-like mechanisms in neurodegenerative diseases

1 reference

12 December 2020

Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases

1 reference

12 December 2020

The Conformation and the Aggregation Kinetics of α-Synuclein Depend on the Proline Residues in Its C-Terminal Region

1 reference

12 December 2020

Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein

1 reference

12 December 2020

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

1 reference

12 December 2020

α-synuclein phosphorylation and truncation are normal events in the adult human brain

1 reference

12 December 2020

Critical role of truncated α-synuclein and aggregates in Parkinson's disease and incidental Lewy body disease

1 reference

12 December 2020

Proteolytic cleavage of extracellular α-synuclein by plasmin: implications for Parkinson disease

1 reference

12 December 2020

Molecular analysis and biochemical classification of TDP-43 proteinopathy

1 reference

12 December 2020

Prion-like spreading of pathological α-synuclein in brain

1 reference

12 December 2020

Lysosomal impairment in Parkinson's disease

1 reference

12 December 2020

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

1 reference

12 December 2020

Structural and functional characterization of two alpha-synuclein strains

1 reference

12 December 2020

Transmission of multiple system atrophy prions to transgenic mice

1 reference

12 December 2020

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.

1 reference

12 December 2020

Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation

1 reference

12 December 2020

Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry

1 reference

12 December 2020

The newly discovered Parkinson's disease associated Finnish mutation (A53E) attenuates α-synuclein aggregation and membrane binding

1 reference

12 December 2020

The role of protein clearance mechanisms in organismal ageing and age-related diseases.

1 reference

12 December 2020

The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.

1 reference

12 December 2020

Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like Propagation

1 reference

12 December 2020

Neurodegeneration: Aggregates feel the strain.

1 reference

12 December 2020

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

1 reference

12 December 2020

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

1 reference

12 December 2020

Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and α-synuclein aggregation

1 reference

12 December 2020

ɑ-Synuclein strains and the variable pathologies of synucleinopathies

1 reference

12 December 2020

α-Synuclein Fibrils Exhibit Gain of Toxic Function, Promoting Tau Aggregation and Inhibiting Microtubule Assembly

1 reference

12 December 2020

Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology

1 reference

12 December 2020

Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein

1 reference

12 December 2020

Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity

1 reference

12 December 2020

Phosphorylation induces distinct alpha-synuclein strain formation

1 reference

12 December 2020

Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils

1 reference

12 December 2020

Looking at the recent advances in understanding α-synuclein and its aggregation through the proteoform prism.

1 reference

12 December 2020

Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease.

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.RA118.001862

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30030380%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

30030380

1 reference