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IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
scientific article published on 01 April 2002
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Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
title
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
(English)
1 reference
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Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
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10 December 2019
author name string
John P Manis
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
11970883
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
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10 December 2019
Darryll Dudley
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2
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Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
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10 December 2019
Lianne Kaylor
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3
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Europe PubMed Central
PubMed ID
11970883
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
Frederick W Alt
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4
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Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
publication date
1 April 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
volume
16
1 reference
stated in
Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
issue
4
1 reference
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Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
page(s)
607-617
1 reference
stated in
Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
cites work
Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SCID mouse mutant: definition, characterization, and potential uses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence of functional lymphocytes in some (leaky) scid mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku80 is required for immunoglobulin isotype switching
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA rearrangement can account for in vitro switching to IgG1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA end-joining: from yeast to man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential regulatory elements for germline transcription in or near murine Sgamma1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA sequences at immunoglobulin switch region recombination sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Factors and forces controlling V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B cell differentiation and isotype switching is related to division cycle number
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Circular DNA is excised by immunoglobulin class switch recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Towards an understanding of somatic hypermutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linking class-switch recombination with somatic hypermutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanism of immunoglobulin class switch recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ig heavy chain class switching in Rag-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent but biased class switch recombination in the S mu flanking regions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mu switch region tandem repeats are important, but not required, for antibody class switch recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku70 is required for late B cell development and immunoglobulin heavy chain class switching
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism and control of class-switch recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B cell development under the condition of allelic inclusion.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis of somatic hypermutation of immunoglobulin genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Circular DNA is a product of the immunoglobulin class switch rearrangement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Directed Ig class switch recombination in activated murine B cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900306-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(02)00306-0
1 reference
stated in
Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
PubMed ID
11970883
1 reference
stated in
Europe PubMed Central
PubMed ID
11970883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11970883%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
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