(Q91452379)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

review article

1 reference

title

Lysosomes as dynamic regulators of cell and organismal homeostasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

author name string

Juan S Bonifacino

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

publication date

25 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

22 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

page(s)

101-118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

22 April 2020

cites work

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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

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7 January 2021

The Lysosome and Intracellular Signalling

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7 January 2021

Mitochondria and cell signalling

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7 January 2021

Ocular albinism: evidence for a defect in an intracellular signal transduction system

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7 January 2021

The peroxisome as a cell signaling organelle

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7 January 2021

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

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7 January 2021

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

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7 January 2021

mTOR Signaling in Growth, Metabolism, and Disease.

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7 January 2021

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

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7 January 2021

Termination of autophagy and reformation of lysosomes regulated by mTOR

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7 January 2021

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

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7 January 2021

Regulation of TORC1 by Rag GTPases in nutrient response

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7 January 2021

Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.

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7 January 2021

A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold

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7 January 2021

Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex.

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7 January 2021

The lysosome as a cellular centre for signalling, metabolism and quality control

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7 January 2021

Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.

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7 January 2021

Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.

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7 January 2021

Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases

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7 January 2021

Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes

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7 January 2021

Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease

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7 January 2021

Lysosomal Ion Channels as Decoders of Cellular Signals

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7 January 2021

A voltage-dependent K+ channel in the lysosome is required for refilling lysosomal Ca2+ stores.

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7 January 2021

Lysosomal acidification mechanisms

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7 January 2021

Mucolipins: Intracellular TRPML1-3 channels

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Identification of the gene causing mucolipidosis type IV.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The lysosomal Ca2+ release channel TRPML1 regulates lysosome size by activating calmodulin

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https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Mucolipidosis type IV protein TRPML1-dependent lysosome formation

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https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Transcriptional activation of lysosomal exocytosis promotes cellular clearance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosome signaling controls the migration of dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal cell death at a glance.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomes and lysosomal cathepsins in cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal membrane permeabilization and cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Mechanisms of ferroptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Detection and Clearance of Damaged Lysosomes by the Endo-Lysosomal Damage Response and Lysophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis

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7 January 2021

The tripartite motif family identifies cell compartments

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7 January 2021

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

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7 January 2021

Galectins Control mTOR in Response to Endomembrane Damage.

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7 January 2021

ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival

1 reference

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7 January 2021

Triggered recruitment of ESCRT machinery promotes endolysosomal repair.

1 reference

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7 January 2021

The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders

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7 January 2021

Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals.

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7 January 2021

Nucleic acid-sensing TLRs: trafficking and regulation.

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7 January 2021

Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL

1 reference

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7 January 2021

Emerging Roles for the Lysosome in Lipid Metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Phosphoinositides in the control of lysosome function and homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A gene network regulating lysosomal biogenesis and function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB links autophagy to lysosomal biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFE3 regulates whole-body energy metabolism in cooperation with TFEB.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

1 reference

7 January 2021

TFEB and TFE3 are novel components of the integrated stress response

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB controls retromer expression in response to nutrient availability

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Nutrient-sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Transcription Factor EB Controls Metabolic Flexibility during Exercise

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Regulation of TFEB and V-ATPases by mTORC1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Multistep regulation of TFEB by MTORC1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

mTOR-dependent phosphorylation controls TFEB nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

STUB1 regulates TFEB-induced autophagy-lysosome pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Stat3 controls lysosomal-mediated cell death in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

STAT3 associates with vacuolar H-ATPase and regulates cytosolic and lysosomal pH

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

ZKSCAN3 is a master transcriptional repressor of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Protein kinase C controls lysosome biogenesis independently of mTORC1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagosome maturation: An epic journey from the ER to lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

BORC coordinates encounter and fusion of lysosomes with autophagosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Cell Invasion In Vivo via Rapid Exocytosis of a Transient Lysosome-Derived Membrane Domain.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Polarized secretion of lysosomal enzymes: co-distribution of cation-independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosome Fission: Planning for an Exit

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

mTOR regulates phagosome and entotic vacuole fission.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

PtdIns3P controls mTORC1 signaling through lysosomal positioning.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Cholesterol transport through lysosome-peroxisome membrane contacts

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Moving and positioning the endolysosomal system.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A novel kinesin-like protein, KIF1Bbeta3 is involved in the movement of lysosomes to the cell periphery in non-neuronal cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal positioning coordinates cellular nutrient responses.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

BORC, a multisubunit complex that regulates lysosome positioning.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Mechanisms and functions of lysosome positioning

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosome Positioning Influences mTORC2 and AKT Signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Dynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Human cytomegalovirus infection maintains mTOR activity and its perinuclear localization during amino acid deprivation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy: 'Self-Eating' Your Way to Longevity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal storage diseases: from pathophysiology to therapy.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal disorders: from storage to cellular damage

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal storage disorders - challenges, concepts and avenues for therapy: beyond rare diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Emptying the stores: lysosomal diseases and therapeutic strategies

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal storage diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The lysosomal disease caused by mutant VPS33A

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

CORVET, CHEVI and HOPS - multisubunit tethers of the endo-lysosomal system in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A block of autophagy in lysosomal storage disorders

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy in lysosomal storage disorders

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Dysregulation of autophagy as a common mechanism in lysosomal storage diseases.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Modulation of mTOR signaling as a strategy for the treatment of Pompe disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Brain Disorders Due to Lysosomal Dysfunction.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The role of autophagy in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy and Its Comprehensive Impact on ALS.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The Complicated Relationship between Gaucher Disease and Parkinsonism: Insights from a Rare Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Huntingtin functions as a scaffold for selective macroautophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The lysosome: from waste bag to potential therapeutic target

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy and Tumor Metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Extracellular acidification alters lysosomal trafficking in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lipids, lysosomes, and autophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomes in nutrient signalling: A focus on pancreatic β-cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Metabolic regulation through the endosomal system

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

High-fat diet increases autophagic flux in pancreatic beta cells in vivo and ex vivo in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The position of lysosomes within the cell determines their luminal pH

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy modulation as a potential therapeutic target for diverse diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Targeting autophagy in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

TFEB controls vascular development by regulating the proliferation of endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex

1 reference

https://api.crossref.org/works/10.1038%2FS41580-019-0185-4

7 January 2021

10.1038/S41580-019-0185-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31768005%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

1 reference