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New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
scientific article published on 01 February 2019
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Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
title
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
author name string
Anushka Dongre
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
Robert A Weinberg
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
publication date
1 February 2019
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
published in
Nature Reviews Molecular Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
volume
20
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
page(s)
69-84
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
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Correction: The Cellular Prion Protein PrP Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins
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The epigenetics of epithelial-mesenchymal plasticity in cancer
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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
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EMT: when epithelial cells decide to become mesenchymal-like cells
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Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas.
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Molecular mechanisms of epithelial-mesenchymal transition
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Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
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Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease
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The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
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Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.
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ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
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based on heuristic
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Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
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7 January 2021
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The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
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7 January 2021
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The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
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7 January 2021
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Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells
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Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells
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Control of cell behavior during vertebrate development by Slug, a zinc finger gene
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7 January 2021
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Epithelial-mesenchymal transitions: insights from development
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Dynamic behavior of the cadherin-based cell-cell adhesion system during Drosophila gastrulation.
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Cadherin switching during the formation and differentiation of the Drosophila mesoderm - implications for epithelial-to-mesenchymal transitions.
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Establishing neural crest identity: a gene regulatory recipe
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Antagonistic roles of full-length N-cadherin and its soluble BMP cleavage product in neural crest delamination.
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7 January 2021
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Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition
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based on heuristic
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The Snail genes as inducers of cell movement and survival: implications in development and cancer.
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Snail family members and cell survival in physiological and pathological cleft palates
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-mesenchymal transition in tissue repair and fibrosis
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Identification and prognostic significance of an epithelial-mesenchymal transition expression profile in human bladder tumors
1 reference
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7 January 2021
based on heuristic
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A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-mesenchymal transition promotes SOX2 and NANOG expression in bladder cancer.
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-to-mesenchymal transition in the development and progression of adenocarcinoma and squamous cell carcinoma of the lung
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
N-cadherin, a novel prognostic biomarker, drives malignant progression of colorectal cancer
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased TIP30 promotes Snail-mediated epithelial-mesenchymal transition and tumor-initiating properties in hepatocellular carcinoma
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional repressor Snail promotes mammary tumor recurrence
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelotype of colorectal carcinomas
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Slug and Sox9 cooperatively determine the mammary stem cell state
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Upholding a role for EMT in breast cancer metastasis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upholding a role for EMT in pancreatic cancer metastasis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
A collective route to metastasis: Seeding by tumor cell clusters
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7 January 2021
based on heuristic
inferred from DOI database lookup
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-mesenchymal transition in glioblastoma progression
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7 January 2021
based on heuristic
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The Biology of Cancer Invasion and Metastasis
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based on heuristic
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Surviving at a distance: organ specific metastasis
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7 January 2021
based on heuristic
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The cellular basis of kidney development
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7 January 2021
based on heuristic
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Targeting the Epithelial-to-Mesenchymal Transition: The Case for Differentiation-Based Therapy
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based on heuristic
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Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation
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7 January 2021
based on heuristic
inferred from DOI database lookup
Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta and cancer
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7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta-induced epithelial to mesenchymal transition
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta (TGFbeta) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT).
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of TGF-beta in hepatic fibrosis
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition
1 reference
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SUMO guards for SNAIL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial-mesenchymal transition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histone deacetylase 6 inhibition counteracts the epithelial-mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pleiotropic Roles of Non-Coding RNAs in TGF-β-Mediated Epithelial-Mesenchymal Transition and Their Functions in Tumor Progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long non-coding RNAs (LncRNA) regulated by transforming growth factor (TGF) β: LncRNA-hit-mediated TGFβ-induced epithelial to mesenchymal transition in mammary epithelia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of long noncoding RNA function in development and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signalling and its impact on development and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling in cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt/beta-catenin signaling in development and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Wnt3 in vertebrate axis formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial stem cells, wound healing and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling mechanisms of the epithelial-mesenchymal transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer stem cells revisited.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WNT signalling pathways as therapeutic targets in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Snail promotes Wnt target gene expression and interacts with beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SFRP1 reduction results in an increased sensitivity to TGF-β signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Holding their own: the noncanonical roles of Smad proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MicroRNA-300 promotes apoptosis and inhibits proliferation, migration, invasion and epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway by targeting CUL4B in pancreatic cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signalling during peripheral T-cell activation and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signalling in context
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch3 is important for TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer bone metastasis by regulating ZEB-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NOTCH4-HEY1 pathway induces epithelial mesenchymal transition in head and neck squamous cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction growth factors: the effective governance of transcription and cellular adhesion in cancer invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor and transforming growth factor-beta1 enhance HK-2 cell migration through a synergistic increase of matrix metalloproteinase and sustained activation of ERK signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic effect between EGF and TGF-beta1 in inducing oncogenic properties of intestinal epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor-promoting functions of transforming growth factor-β in progression of cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fibroblast growth factor-2-mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analyses of publicly available genomics resources define FGF-2-expressing bladder carcinomas as EMT-prone, proliferative tumors with low mutation rates and high expression of CTLA-4, PD-1 and PD-L1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic upregulation of HGF and c-Met drives metastasis in hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High circulating hepatocyte growth factor levels associate with epithelial to mesenchymal transition and poor outcome in small cell lung cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting met mediated epithelial-mesenchymal transition in the treatment of breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MiR-206 inhibits HGF-induced epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via c-Met /PI3k/Akt/mTOR pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MiR-182 inhibits the epithelial to mesenchymal transition and metastasis of lung cancer cells by targeting the Met gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-6 Secreted from Cancer-Associated Fibroblasts Mediates Chemoresistance in NSCLC by Increasing Epithelial-Mesenchymal Transition Signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An integrated analysis identifies STAT4 as a key regulator of ovarian cancer metastasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Breast cancer-associated fibroblasts induce epithelial-to-mesenchymal transition in breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HER-2/neu antigen loss and relapse of mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage diversity enhances tumor progression and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6-mediated COX-2/PGE2/β-catenin signalling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myeloid-derived suppressor cells as regulators of the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leukocyte composition of human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular constituents of immune escape within the tumor microenvironment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Innate and adaptive immune cells in the tumor microenvironment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta and the immune response: implications for anticancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta and the immune response to malignant disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CCL2 is critical for immunosuppression to promote cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathways of antigen processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class I antigens, immune surveillance, and tumor immune escape.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Major histocompatibility complex class i and tumour immuno-evasion: how to fool T cells and natural killer cells at one time
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EMT, cell plasticity and metastasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tackling the cancer stem cells - what challenges do they pose?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FS41580-018-0080-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/S41580-018-0080-4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
PubMed publication ID
30459476
1 reference
stated in
Europe PubMed Central
PubMed publication ID
30459476
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30459476%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 May 2020
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