(Q94500293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

title

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

1 reference

spike glycoprotein [SARS-CoV-2]

1 reference

based on heuristic

inferred from abstract

author name string

Markus Hoffmann

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

Hannah Kleine-Weber

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

Stefan Pöhlmann

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

publication date

28 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

A vesicular stomatitis virus replicon-based bioassay for the rapid and sensitive determination of multi-species type I interferon

15 May 2020

cites work

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Differential sensitivity of bat cells to infection by enveloped RNA viruses: coronaviruses, paramyxoviruses, filoviruses, and influenza viruses

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Coronavirus Spike Protein and Tropism Changes

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Mutations in the spike protein of MERS-CoV transmitted in Korea increase resistance towards antibody-mediated neutralization

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

YASARA View - molecular graphics for all devices - from smartphones to workstations

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Identifying SARS-CoV-2 related coronaviruses in Malayan pangolins

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Molecular pathogenesis of H5 highly pathogenic avian influenza: the role of the haemagglutinin cleavage site motif

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

The EMBL-EBI search and sequence analysis tools APIs in 2019

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Comparison of vesicular stomatitis virus pseudotyped with the S proteins from a porcine and a human coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

A novel coronavirus outbreak of global health concern

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

Protease inhibitors targeting coronavirus and filovirus entry

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

A pneumonia outbreak associated with a new coronavirus of probable bat origin

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

A Novel Coronavirus from Patients with Pneumonia in China, 2019

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194065

A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein

26 July 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7194065

10.1016/J.MOLCEL.2020.04.022

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 May 2020

COVIDWHO ID

covidwho-88548

0 references

1127259675

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32362314%20AND%20SRC:MED&resulttype=core&format=json