(Q107341961)

1

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Ke Shi

2

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Surajit Banerjee

4

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Lulu Yin

5

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Christopher Belica

6

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Cameron Durfee

7

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Rommie E Amaro

8

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Hideki Aihara

Structure of replicating SARS-CoV-2 polymerase

9

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language of work or name

English

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publication date

4 April 2021

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cites work

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274

Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes

25 June 2021

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Continuous and Discontinuous RNA Synthesis in Coronaviruses

25 June 2021

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Mutation rates among RNA viruses

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Rates of molecular evolution in RNA viruses: a quantitative phylogenetic analysis

25 June 2021

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25 June 2021

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Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity

25 June 2021

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Nidovirales: evolving the largest RNA virus genome

25 June 2021

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Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

25 June 2021

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Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis

25 June 2021

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Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting

25 June 2021

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Coronaviruses as DNA wannabes: a new model for the regulation of RNA virus replication fidelity

25 June 2021

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Mutations of SARS-CoV-2 nsp14 exhibit strong association with increased genome-wide mutation load

25 June 2021

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Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

25 June 2021

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High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.

25 June 2021

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A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease

25 June 2021

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The enzymatic activity of the nsp14 exoribonuclease is critical for replication of MERS-CoV and SARS-CoV-2

25 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274

Murine hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.

25 June 2021

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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

25 June 2021

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Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

25 June 2021

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Biochemical characterization of exoribonuclease encoded by SARS coronavirus

25 June 2021

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Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

25 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274

Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification

25 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274

Structure of DNA polymerase I Klenow fragment bound to duplex DNA

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

25 June 2021

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Phasercrystallographic software

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Features and development of Coot

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Scalable molecular dynamics on CPU and GPU architectures with NAMD

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories.

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

Electrostatics of nanosystems: application to microtubules and the ribosome

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

New targets for drug design: Importance of nsp14/nsp10 complex formation for the 3’-5’ exoribonucleolytic activity on SARS-CoV-2

25 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274

Genomic diversity of SARS-CoV-2 can be accelerated by a mutation in the nsp14 gene

25 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274

Novel Zinc Protein Molecular Dynamics Simulations: Steps Toward Antiangiogenesis for Cancer Treatment

25 June 2021

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https://api.crossref.org/works/10.1101/2021.04.02.438274

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

25 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.04.02.438274