(Q24296951)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

John Kuriyan

8

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Holger Sondermann

2

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Michelle Pirruccello

1

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Jonathan Chernoff

object named as

Jonathan Chernoff

6

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author name string

Jeffrey G Pelton

3

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Patricia Pellicena

4

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André Hoelz

5

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David E Wemmer

Journal of Molecular Biology

7

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language of work or name

English

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publication date

11 August 2006

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published in

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volume

361

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issue

2

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page(s)

312-26

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cites work

Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.

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LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome

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Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

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Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

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PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking

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Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2

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The active conformation of the PAK1 kinase domain

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Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

1 reference

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7 January 2021

How do protein kinases recognize their substrates?

1 reference

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7 January 2021

HIV-1: is Nef a PAK animal?

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7 January 2021

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

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The Ste20 group kinases as regulators of MAP kinase cascades

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Recognition and specificity in protein tyrosine kinase-mediated signalling

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

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7 January 2021

Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2

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Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1

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p21-activated kinases: three more join the Pak.

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Pheromone response, mating and cell biology

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Characterization of pp60c-src Tyrosine Kinase Activities Using a Continuous Assay: Autoactivation of the Enzyme Is an Intermolecular Autophosphorylation Process

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Determinants for substrate phosphorylation by p21-activated protein kinase (gamma-PAK).

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Autophosphorylation and protein kinase activity of p21-activated protein kinase gamma-PAK are differentially affected by magnesium and manganese

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P21-activated kinases in human cancer

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A homochiral metal-organic porous material for enantioselective separation and catalysis

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Rho GTPases in neuronal morphogenesis

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Structure of Cdc42 bound to the GTPase binding domain of PAK

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7 January 2021

Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

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7 January 2021

Activation of an S6/H4 kinase (PAK 65) from human placenta by intramolecular and intermolecular autophosphorylation

1 reference

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7 January 2021

Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family

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7 January 2021

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.06.017

7 January 2021

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

1 reference

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7 January 2021

Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity

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7 January 2021

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

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7 January 2021

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

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7 January 2021

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

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7 January 2021

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

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7 January 2021

p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

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7 January 2021

The mechanism of p21-activated kinase 2 autoactivation.

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7 January 2021

The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition

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7 January 2021

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

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7 January 2021

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

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7 January 2021

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

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7 January 2021

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

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7 January 2021

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

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7 January 2021

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

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7 January 2021

Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation

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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.06.017

7 January 2021

Conformational switch and role of phosphorylation in PAK activation

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7 January 2021

Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation

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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.06.017

7 January 2021

GIT1 activates p21-activated kinase through a mechanism independent of p21 binding

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7 January 2021

Biology of the p21-activated kinases

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7 January 2021

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7 January 2021