(Q24814522)

22 June 2017

title

Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation (English)

1 reference

22 June 2017

Levent Sari

1

1 reference

22 June 2017

Ioan Andricioaei

series ordinal

2

1 reference

22 June 2017

language of work or name

English

0 references

publication date

27 November 2005

1 reference

22 June 2017

published in

Nucleic Acids Research

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22 June 2017

volume

33

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22 June 2017

issue

20

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22 June 2017

page(s)

6621-6634

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DNA topoisomerases: structure, function, and mechanism

22 June 2017

cites work

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Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule

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Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands

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Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro

7 April 2017

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Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures

7 April 2017

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Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases

28 September 2017

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Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality.

28 September 2017

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28 September 2017

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DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Structure and hydration of the DNA-human topoisomerase I covalent complex.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Forced unfolding of fibronectin type 3 modules: an analysis by biased molecular dynamics simulations

28 September 2017

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Reconstitution of human topoisomerase I by fragment complementation

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Normal modes for specific motions of macromolecules: application to the hinge-bending mode of lysozyme

28 September 2017

1 reference

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DNA gyrase: an enzyme that introduces superhelical turns into DNA

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Conversion between three conformational states of integrin I domains with a C-terminal pull spring studied with molecular dynamics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Simplified normal mode analysis of conformational transitions in DNA-dependent polymerases: the elastic network model

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Nanoseconds molecular dynamics simulation of primary mechanical energy transfer steps in F1-ATP synthase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Conformational change of proteins arising from normal mode calculations

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Expression, purification and DNA-cleavage activity of recombinant 68-kDa human topoisomerase I-target for antitumor drugs.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Ligand-induced conformational changes in ras p21: a normal mode and energy minimization analysis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Interaction between DNA and an Escherichia coli protein omega

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Active site dynamics in protein molecules: a stochastic boundary molecular-dynamics approach.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

A normal mode analysis of structural plasticity in the biomolecular motor F(1)-ATPase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Thermophilic topoisomerase I on a single DNA molecule

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

19F NMR studies of vaccinia type IB topoisomerase. Conformational dynamics of the bound DNA substrate

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Fluorescence spectroscopy studies of vaccinia type IB DNA topoisomerase. Closing of the enzyme clamp is faster than DNA cleavage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Residues within the N-terminal Domain of Human Topoisomerase I Play a Direct Role in Relaxation*

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Positive torsional strain causes the formation of a four-way junction at replication forks

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Diversity of DNA topoisomerases I and inhibitors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

Covalent DNA binding by vaccinia topoisomerase results in unpairing of the thymine base 5' of the scissile bond.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1298917

The conformation of constitutive DNA interaction sites for eukaryotic DNA topoisomerase I on intrinsically curved DNAs

28 November 2018

1 reference

12 December 2020

Purification of a DNA topoisomerase II from the hyperthermophilic archaeon Sulfolobus shibatae. A thermostable enzyme with both bacterial and eucaryal features

1 reference

12 December 2020

Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation

1 reference

12 December 2020

Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop

1 reference

12 December 2020

Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin

1 reference

12 December 2020

Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKI935

1 reference

22 June 2017

0 references

1 reference