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The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation
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title
The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation
(English)
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author name string
Grant A. Hartzog
series ordinal
1
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Crossref
Jianhua Fu
series ordinal
2
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language of work or name
English
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publication date
January 2013
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published in
Biochimica et Biophysica Acta
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PubMed
volume
1829
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PubMed
issue
1
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PubMed
page(s)
105-15
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PubMed
cites work
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Human mediator subunit MED26 functions as a docking site for transcription elongation factors
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c-Myc regulates transcriptional pause release
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Regulator trafficking on bacterial transcription units in vivo
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21 March 2017
Analysis of a splice array experiment elucidates roles of chromatin elongation factor Spt4-5 in splicing
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21 March 2017
Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5
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Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex
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21 March 2017
Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences
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21 March 2017
Domains in the SPT5 protein that modulate its transcriptional regulatory properties
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21 March 2017
Transcription elongation factor hSPT5 stimulates mRNA capping
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21 March 2017
Structure and function of the human transcription elongation factor DSIF
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21 March 2017
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
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Isolation and characterization of the human and mouse homologues (SUPT4H and Supt4h) of the yeast SPT4 gene
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21 March 2017
Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae
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21 March 2017
The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
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21 March 2017
Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity
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21 March 2017
Structural basis of RNA polymerase II backtracking, arrest and reactivation
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RNA polymerase and transcription elongation factor Spt4/5 complex structure
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21 March 2017
A NusE:NusG complex links transcription and translation
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21 March 2017
Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif
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21 March 2017
Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface
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21 March 2017
Two Structurally Independent Domains of E. coli NusG Create Regulatory Plasticity via Distinct Interactions with RNA Polymerase and Regulators
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21 March 2017
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
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Crystal structure of NusG N-terminal (NGN) domain from Methanocaldococcus jannaschii and its interaction with rpoE''
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Structural Basis for Converting a General Transcription Factor into an Operon-Specific Virulence Regulator
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Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage
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Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution
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Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution
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Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution
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A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast
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21 March 2017
The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively
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21 March 2017
Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly.
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21 March 2017
Uniform transitions of the general RNA polymerase II transcription complex
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21 March 2017
Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.
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Activation of a poised RNAPII-dependent promoter requires both SAGA and mediator
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21 March 2017
The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair
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21 March 2017
Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex
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21 March 2017
Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription
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Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5.
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21 March 2017
The small hSpt4 subunit of the human transcription elongation factor DSIF is a Zn-finger protein with α/β type topology
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21 March 2017
Functions of Saccharomyces cerevisiae TFIIF during transcription start site utilization
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21 March 2017
RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing
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21 March 2017
The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.
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21 March 2017
A functional role for the switch 2 region of yeast RNA polymerase II in transcription start site utilization and abortive initiation
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21 March 2017
BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex
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21 March 2017
Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II.
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21 March 2017
Interaction between transcription elongation factors and mRNA 3'-end formation at the Saccharomyces cerevisiae GAL10-GAL7 locus.
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21 March 2017
mRNA capping enzyme activity is coupled to an early transcription elongation
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21 March 2017
Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae
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21 March 2017
Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes
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21 March 2017
Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins
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PubMed Central
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21 March 2017
Molecular evidence for a positive role of Spt4 in transcription elongation
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21 March 2017
Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo
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PubMed Central
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21 March 2017
The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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21 March 2017
Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae
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21 March 2017
Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae
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21 March 2017
Roles for both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II
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21 March 2017
c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis
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21 March 2017
Methylation of SPT5 Regulates Its Interaction with RNA Polymerase II and Transcriptional Elongation Properties
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PubMed Central
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21 March 2017
Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex
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21 March 2017
A highly purified RNA polymerase II elongation control system
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21 March 2017
DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation
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PubMed Central
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21 March 2017
NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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21 March 2017
The human Mediator complex: a versatile, genome-wide regulator of transcription
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21 March 2017
Controlling the elongation phase of transcription with P-TEFb
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PubMed Central
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21 March 2017
Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila
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PubMed Central
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21 March 2017
Genetic interactions of Spt4-Spt5 and TFIIS with the RNA polymerase II CTD and CTD modifying enzymes in Saccharomyces cerevisiae
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21 March 2017
Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 Tat-activation
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PubMed Central
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21 March 2017
Promoter clearance by RNA polymerase II is an extended, multistep process strongly affected by sequence
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PubMed Central
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21 March 2017
Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo
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7 April 2017
Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases
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7 April 2017
Regulation of mammalian transcription by Gdown1 through a novel steric crosstalk revealed by cryo-EM
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28 September 2017
The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination
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28 September 2017
Coupling polymerase pausing and chromatin landscapes for precise regulation of transcription.
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28 September 2017
Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Spt4 is selectively required for transcription of extended trinucleotide repeats
1 reference
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PubMed Central
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28 September 2017
A nexus for gene expression-molecular mechanisms of Spt5 and NusG in the three domains of life
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PubMed Central
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28 September 2017
The spt5 C-terminal region recruits yeast 3' RNA cleavage factor I.
1 reference
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PubMed Central
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28 September 2017
Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Independent chromatin binding of ARGONAUTE4 and SPT5L/KTF1 mediates transcriptional gene silencing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Evolution of multisubunit RNA polymerases in the three domains of life.
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PubMed Central
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28 September 2017
Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
A dual interface determines the recognition of RNA polymerase II by RNA capping enzyme.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Separable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTD
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Plant-specific multisubunit RNA polymerase in gene silencing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Functional regions of the N-terminal domain of the antiterminator RfaH.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
CDK8 is a positive regulator of transcriptional elongation within the serum response network
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The Paf1 complex: platform or player in RNA polymerase II transcription?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
An effector of RNA-directed DNA methylation in arabidopsis is an ARGONAUTE 4- and RNA-binding protein.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
RNA Pol II accumulates at promoters of growth genes during developmental arrest.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The elongation factor RfaH and the initiation factor sigma bind to the same site on the transcription elongation complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Interplay between E-box and NF-kappaB in regulation of A20 gene by DRB sensitivity-inducing factor (DSIF).
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Differential regulation of NF-kappaB by elongation factors is determined by core promoter type
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Identification of a regulator of transcription elongation as an accessory factor for the human Mediator coactivator.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Breaking barriers to transcription elongation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
retrieved
28 September 2017
The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Newly Initiated RNA encounters a factor involved in splicing immediately upon emerging from within RNA polymerase II.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Transcriptional elongation control by RNA polymerase II: a new frontier
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-kappaB.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
In Vivo Evidence that Defects in the Transcriptional Elongation Factors RPB2, TFIIS, and SPT5 Enhance Upstream Poly(A) Site Utilization
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The initiation-elongation transition: lateral mobility of RNA in RNA polymerase II complexes is greatly reduced at +8/+9 and absent by +23.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The genetic core of the universal ancestor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Promoting elongation with transcript cleavage stimulatory factors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Novel domains and orthologues of eukaryotic transcription elongation factors.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Transcription elongation factor Spt4 mediates loss of phosphorylated RNA polymerase II transcription in response to DNA damage
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Transcription elongation complex: structure and function
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Spt4 modulates Rad26 requirement in transcription-coupled nucleotide excision repair
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
A new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Binding of TFIID to the CYC1 TATA boxes in yeast occurs independently of upstream activating sequences
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Escherichia coli NusG protein stimulates transcription elongation rates in vivo and in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 September 2017
Mutual remodeling and conformation grid: a mediator code?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
Allosteric control of the RNA polymerase by the elongation factor RfaH
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
DSIF contributes to transcriptional activation by DNA-binding activators by preventing pausing during transcription elongation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
Combinatorial effects of NusA and NusG on transcription elongation and Rho-dependent termination in Escherichia coli
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
Tudor domains in proteins that interact with RNA.
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31 May 2018
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription elongation by RNA polymerase II in vitro.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
NusG, a new Escherichia coli elongation factor involved in transcriptional antitermination by the N protein of phage lambda
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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31 May 2018
Competing for the clamp: promoting RNA polymerase processivity and managing the transition from initiation to elongation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Tudor Domain
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PubMed Central
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28 November 2018
A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Genome-wide analyses reveal RNA polymerase II located upstream of genes poised for rapid response upon S. cerevisiae stationary phase exit.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Exploring functional relationships between components of the gene expression machinery.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Analysis of polymerase II elongation complexes by native gel electrophoresis. Evidence for a novel carboxyl-terminal domain-mediated termination mechanism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Intrinsic transcript cleavage in yeast RNA polymerase II elongation complexes
1 reference
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PubMed Central
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28 November 2018
A key role for the alpha 1 helix of human RAP74 in the initiation and elongation of RNA chains.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
RNA polymerase II and TBP occupy the repressed CYC1 promoter
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
A regulator of transcriptional elongation controls vertebrate neuronal development
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
retrieved
28 November 2018
Mutational analysis of beta '260-309, a sigma 70 binding site located on Escherichia coli core RNA polymerase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Functional analysis of Drosophila factor 5 (TFIIF), a general transcription factor.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545043
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28 November 2018
Antiterminator-dependent modulation of transcription elongation rates by NusB and NusG
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22982195
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNAP subunits F/E (RPB4/7) are stably associated with archaeal RNA polymerase: using fluorescence anisotropy to monitor RNAP assembly in vitro
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nature of the nucleosomal barrier to RNA polymerase II
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22982195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBAGRM.2012.08.007
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4839601
OpenCitations bibliographic resource ID
4839601
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4839601
PMC publication ID
3545043
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4839601
PubMed publication ID
22982195
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4839601
ResearchGate publication ID
230862814
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