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Tumor suppressor p53 and its gain-of-function mutants in cancer
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title
Tumor suppressor p53 and its gain-of-function mutants in cancer
(English)
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main subject
biophysics
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author name string
J. Liu
series ordinal
1
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stated in
Crossref
C. Zhang
series ordinal
2
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Crossref
Z. Feng
series ordinal
3
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Crossref
language of work or name
English
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stated in
PubMed
publication date
March 2014
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stated in
PubMed
published in
Acta Biochimica et Biophysica Sinica
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stated in
PubMed
volume
46
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stated in
PubMed
issue
3
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stated in
PubMed
page(s)
170-9
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PubMed
cites work
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
1 reference
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PubMed Central
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21 March 2017
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer
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PubMed Central
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21 March 2017
Hallmarks of Cancer: The Next Generation
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PubMed Central
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21 March 2017
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Modulation of the vitamin D3 response by cancer-associated mutant p53
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
The first 30 years of p53: growing ever more complex
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PubMed Central
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21 March 2017
Regulation of autophagy by cytoplasmic p53
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Mutant p53 proteins bind DNA in a DNA structure-selective mode
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Suppression of tumorigenesis by the p53 target PUMA
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
ASPP proteins specifically stimulate the apoptotic function of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Surfing the p53 network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Definition of a consensus binding site for p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
A microRNA component of the p53 tumour suppressor network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
p53 regulates mitochondrial respiration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
21 March 2017
14-3-3sigma is a p53-regulated inhibitor of G2/M progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
p53 mutations in human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
The p53-induced gene Ei24 is an essential component of the basal autophagy pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
21 March 2017
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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21 March 2017
Blinded by the Light: The Growing Complexity of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
p53 and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Modulation of microRNA processing by p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Transcriptional control of human p53-regulated genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Restoration of p53 function leads to tumour regression in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
p53 ubiquitination: Mdm2 and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
The antioxidant function of the p53 tumor suppressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
The p53 pathway: positive and negative feedback loops
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
p53 is required for radiation-induced apoptosis in mouse thymocytes
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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7 April 2017
Radiation-induced cell cycle arrest compromised by p21 deficiency
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PubMed Central
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7 April 2017
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1 reference
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PubMed Central
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7 April 2017
Tumour-associated mutant p53 drives the Warburg effect
1 reference
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PubMed Central
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28 September 2017
Advances in adenovirus-mediated p53 cancer gene therapy
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PubMed Central
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28 September 2017
Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression
1 reference
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PubMed Central
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28 September 2017
The regulation of cellular metabolism by tumor suppressor p53.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
MDM2, MDMX and p53 in oncogenesis and cancer therapy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
p53 mutations in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
MicroRNAs in the p53 network: micromanagement of tumour suppression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Mutant p53: one name, many proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Allele-specific p53 mutant reactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
The dynamic nature of autophagy in cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Subchronic oral toxicity and metabolite profiling of the p53 stabilizing agent, CP-31398, in rats and dogs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Tumor suppressor p53 meets microRNAs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
MI-219-zinc combination: a new paradigm in MDM2 inhibitor-based therapy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
The p53 tumor suppressor: a master regulator of diverse cellular processes and therapeutic target in cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Autophagy regulation by p53.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
When mutants gain new powers: news from the mutant p53 field.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Cytoplasmic functions of the tumour suppressor p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
The mitochondrial p53 pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
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28 September 2017
Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
p53: new roles in metabolism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Regulation of AIF expression by p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
The coordinate regulation of the p53 and mTOR pathways in cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
The role of TP53 in Cervical carcinogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
General keynote: hereditary cancer: lessons from Li-Fraumeni syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Dissecting p53 tumor suppressor functions in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Mutant p53 forms a complex with Sp1 on HIV-LTR DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Specific binding of MAR/SAR DNA-elements by mutant p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Clinical implications of the p53 tumor-suppressor gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
28 September 2017
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
Gain of function mutations in p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3932832
retrieved
31 May 2018
Thymocyte apoptosis induced by p53-dependent and independent pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FABBS%2FGMT144
retrieved
21 January 2018
p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FABBS%2FGMT144
retrieved
21 January 2018
Mutant p53 protein localized in the cytoplasm inhibits autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FABBS%2FGMT144
retrieved
21 January 2018
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FABBS%2FGMT144
retrieved
21 January 2018
p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FABBS%2FGMT144
retrieved
21 January 2018
Promyelocytic leukemia protein is required for gain of function by mutant p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FABBS%2FGMT144
retrieved
21 January 2018
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24374774
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24374774
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/ABBS/GMT144
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3861509
OpenCitations bibliographic resource ID
3861509
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3861509
PMCID
3932832
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3861509
PubMed ID
24374774
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3861509
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