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Heterogeneity of glycolysis in cancers and therapeutic opportunities
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PubMed
title
Heterogeneity of glycolysis in cancers and therapeutic opportunities
(English)
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stated in
PubMed
author
Marc O. Warmoes
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
Jason W. Locasale
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
author name string
Warmoes MO
series ordinal
1
1 reference
stated in
PubMed
Locasale JW
series ordinal
2
1 reference
stated in
PubMed
language of work or name
English
0 references
publication date
1 November 2014
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stated in
PubMed
published in
Biochemical Pharmacology
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
volume
92
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
issue
1
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
page(s)
12-21
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
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29 September 2017
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors
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29 September 2017
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
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29 September 2017
Cancer metabolism: what we can learn from proteomic analysis by mass spectrometry
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
Regulation of Aerobic Glycolysis by microRNAs in Cancer
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29 September 2017
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29 September 2017
Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
The importance of post-translational modifications in regulating Saccharomyces cerevisiae metabolism.
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29 September 2017
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29 September 2017
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29 September 2017
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial
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29 September 2017
Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?
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29 September 2017
Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism
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29 September 2017
Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.
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29 September 2017
Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease
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29 September 2017
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29 September 2017
Liver glucokinase: An overview on the regulatory mechanisms of its activity
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29 September 2017
α-Enolase: a promising therapeutic and diagnostic tumor target.
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29 September 2017
Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism
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29 September 2017
Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.
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29 September 2017
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
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29 September 2017
Glucose metabolism in mammalian cell culture: new insights for tweaking vintage pathways
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29 September 2017
Metabolic control analysis indicates a change of strategy in the treatment of cancer
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29 September 2017
AMPK as a metabolic tumor suppressor: control of metabolism and cell growth
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29 September 2017
Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells
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29 September 2017
Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments
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29 September 2017
HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.
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29 September 2017
Enzymatic properties of the N- and C-terminal halves of human hexokinase II.
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29 September 2017
Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.
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29 September 2017
Monitoring and predicting response to therapy with 18F-FDG PET in colorectal cancer: a systematic review.
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29 September 2017
Clinical applications of metabolomics in oncology: a review
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29 September 2017
Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis
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29 September 2017
Tumor cell metabolism imaging
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29 September 2017
Assignment and expression patterns of porcine muscle-specific isoform of phosphoglycerate mutase gene
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29 September 2017
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death
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29 September 2017
Investigation of glyceraldehyde-3-phosphate dehydrogenase from human sperms
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29 September 2017
Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.
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29 September 2017
Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase
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29 September 2017
Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells
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29 September 2017
Chemotherapeutic approaches for targeting cell death pathways
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29 September 2017
Novel formulations of taxanes: a review. Old wine in a new bottle?
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29 September 2017
Activation of AKT kinases in cancer: implications for therapeutic targeting
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29 September 2017
Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.
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29 September 2017
Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo.
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29 September 2017
The non-competitive inhibition of brain hexokinase by glucose-6-phosphate and related compounds.
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29 September 2017
Evolution of the coordinate regulation of glycolytic enzyme genes by hypoxia
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29 September 2017
Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function
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29 September 2017
Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways
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29 September 2017
A review of animal phosphofructokinase isozymes with an emphasis on their physiological role
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29 September 2017
Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?
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2 June 2018
Western blots versus selected reaction monitoring assays: time to turn the tables?
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2 June 2018
Characterization of alpha alpha, beta beta, gamma gamma and alpha gamma human enolase isozymes, and preparation of hybrid enolases (alpha gamma, beta gamma and alpha beta) from homodimeric forms.
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2 June 2018
A comparative study of aldolase from human muscle and liver
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2 June 2018
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2 June 2018
Alterations in the activity and isozymic profile of human phosphofructokinase during malignant transformation in vivo and in vitro: transformation- and progression-linked discriminants of malignancy.
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Subunit composition, regulatory properties, and phosphorylation of phosphofructokinase from human gliomas.
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2 June 2018
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.
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HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.
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Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study.
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27 November 2018
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27 November 2018
Dichloroacetate shifts the metabolism from glycolysis to glucose oxidation and exhibits synergistic growth inhibition with cisplatin in HeLa cells.
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27 November 2018
Targeting glucose metabolism with 2-deoxy-D-glucose for improving cancer therapy.
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27 November 2018
2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
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Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254151
retrieved
27 November 2018
Transcriptome meets metabolome: hierarchical and metabolic regulation of the glycolytic pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254151
retrieved
27 November 2018
Nutrition needs of mammalian cells in tissue culture
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A common phosphorylation site for cyclic AMP-dependent protein kinase and protein kinase C in human placental 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A metabolomics approach for predicting the response to neoadjuvant chemotherapy in cervical cancer patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Comparative kinetic behaviour and regulation by fructose-1,6-bisphosphate and ATP of pyruvate kinase from erythrocytes, reticulocytes and bone marrow cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of glycolytic isoenzymes in activated human peripheral lymphocytes: cell cycle analysis using flow cytometry
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Modeling cancer glycolysis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25093285
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BCP.2014.07.019
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3361557
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
OpenCitations bibliographic resource ID
3361557
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3361557
PMC publication ID
4254151
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3361557
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PubMed publication ID
25093285
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3361557
stated in
Europe PubMed Central
PMC publication ID
4254151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25093285%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
ResearchGate publication ID
264424052
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