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PHD2: from hypoxia regulation to disease progression
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instance of
scholarly article
1 reference
stated in
PubMed
review article
1 reference
stated in
Europe PubMed Central
title
PHD2: from hypoxia regulation to disease progression
(English)
1 reference
stated in
PubMed
main subject
hypoxia
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based on heuristic
inferred from title
author
Ben Wielockx
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
author name string
Ana M Meneses
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
language of work or name
English
1 reference
stated in
PubMed
publication date
11 April 2016
1 reference
stated in
PubMed
published in
Hypoxia (Auckland, N.Z.)
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
volume
4
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
page(s)
53-67
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
copyright license
Creative Commons Attribution-NonCommercial 3.0 Unported
start time
1 April 2016
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
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Prolyl hydroxylase domain protein 2 regulates the intracellular cyclic AMP level in cardiomyocytes through its interaction with phosphodiesterase 4D
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The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
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Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1
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mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha
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A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis
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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha
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Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing
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von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination
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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling
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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
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20 March 2017
A conserved family of prolyl-4-hydroxylases that modify HIF
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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
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The Hallmarks of Cancer
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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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20 March 2017
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
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20 March 2017
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
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20 March 2017
Inhibition of HIF prolyl hydroxylase-2 blocks tumor growth in mice through the antiproliferative activity of TGFβ
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20 March 2017
Hypoxia in cancer: significance and impact on clinical outcome
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20 March 2017
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
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20 March 2017
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
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20 March 2017
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
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20 March 2017
Exploiting tumour hypoxia in cancer treatment
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Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation
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The impact of O2 availability on human cancer
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Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
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Oxygen sensing by HIF hydroxylases
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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
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Pharmacological targeting of the HIF hydroxylases--A new field in medicine development
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29 September 2017
HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond
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29 September 2017
Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis
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29 September 2017
The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts
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29 September 2017
RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect
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29 September 2017
Hypoxia-inducible miR-182 enhances HIF1α signaling via targeting PHD2 and FIH1 in prostate cancer
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29 September 2017
PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.
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29 September 2017
Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes.
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29 September 2017
A lactate-induced response to hypoxia.
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29 September 2017
Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia
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29 September 2017
Adipocyte pseudohypoxia suppresses lipolysis and facilitates benign adipose tissue expansion.
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29 September 2017
Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability
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29 September 2017
Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment
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29 September 2017
Silencing of hypoxia-inducible factor-1α gene attenuates chronic ischemic renal injury in two-kidney, one-clip rats
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29 September 2017
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters
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29 September 2017
Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver
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29 September 2017
Role of hypoxia in progressive chronic kidney disease and implications for therapy
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29 September 2017
Wound healing improvement with PHD-2 silenced fibroblasts in diabetic mice
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29 September 2017
Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer
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29 September 2017
A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism
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29 September 2017
Inhibition of hypoxia-inducible factor prolyl hydroxylase domain oxygen sensors: tricking the body into mounting orchestrated survival and repair responses
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29 September 2017
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
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29 September 2017
Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development.
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29 September 2017
Erythrocytosis: the HIF pathway in control.
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29 September 2017
Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment.
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29 September 2017
RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells
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29 September 2017
Angiogenesis and hypoxia in the kidney
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29 September 2017
Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathway
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29 September 2017
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis
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29 September 2017
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
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29 September 2017
Hypoxia-inducible factors as key regulators of tumor inflammation
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29 September 2017
Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling
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29 September 2017
HIF prolyl hydroxylase-2 inhibition diminishes tumor growth through matrix metalloproteinase-induced TGFβ activation
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29 September 2017
Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia
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29 September 2017
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis
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29 September 2017
Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia
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29 September 2017
Oxygen sensing, homeostasis, and disease
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29 September 2017
HIF-1α in epidermis: oxygen sensing, cutaneous angiogenesis, cancer, and non-cancer disorders.
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PubMed Central
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29 September 2017
Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Hypoxia inducible factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.
1 reference
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PubMed Central
reference URL
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29 September 2017
Reactivation of hepatic EPO synthesis in mice after PHD loss
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
The role of HIF prolyl hydroxylases in tumour growth.
1 reference
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29 September 2017
Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
In vivo functions of the prolyl-4-hydroxylase domain oxygen sensors: direct route to the treatment of anaemia and the protection of ischaemic tissues
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Stimulation of collateral artery growth: travelling further down the road to clinical application
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
Cellular response to tissue hypoxia and its involvement in disease progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
The histological structure of some human lung cancers and the possible implications for radiotherapy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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29 September 2017
Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
Regulation of the erythropoietin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
29 September 2017
Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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2 June 2018
Deletion of phd2 in myeloid lineage attenuates hypertensive cardiovascular remodeling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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2 June 2018
PHD2 regulates arteriogenic macrophages through TIE2 signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
2 June 2018
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
2 June 2018
A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
2 June 2018
Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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2 June 2018
HIF-1 and HIF-2: working alone or together in hypoxia?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
2 June 2018
Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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2 June 2018
A Novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (GSK1278863) for Anemia in CKD: A 28-Day, Phase 2A Randomized Trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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27 November 2018
SnapShot: Hypoxia-Inducible Factors.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Acellular dermal matrix-based gene therapy augments graft incorporation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Prolyl hydroxylase domain-2 (PHD2) inhibition may be a better therapeutic strategy in renal anemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Deficiency of the oxygen sensor PHD1 augments liver regeneration after partial hepatectomy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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27 November 2018
Role of the intracellular localization of HIF-prolyl hydroxylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
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27 November 2018
PHD2 mutation and congenital erythrocytosis with paraganglioma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
2-Methoxyestradiol (2-ME) reduces the airway inflammation and remodeling in an experimental mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Disturbance in the HIF-1alpha pathway associated with erythrocytosis: further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
AKAP12 regulates human blood-retinal barrier formation by downregulation of hypoxia-inducible factor-1alpha.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085284
retrieved
27 November 2018
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27800508
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Low expression of prolyl hydroxylase 2 is associated with tumor grade and poor prognosis in patients with colorectal cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27800508
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypoxia Response in Asthma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27800508
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27800508
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2147/HP.S53576
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4904744
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
OpenCitations bibliographic resource ID
4904744
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4904744
PMCID
5085284
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4904744
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
PubMed ID
27800508
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4904744
stated in
Europe PubMed Central
PMCID
5085284
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800508%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
ResearchGate publication ID
301206765
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