(Q28257991)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

0 references

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

7

Marie Dutreix

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Maria Quanz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Aurélie Herbette

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Mano Sayarath

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Leanne de Koning

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jian-Sheng Sun

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

23 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

8803-8815

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

21 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3308794/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3308794/fullTextXML

inferred from PubMed Central ID database lookup

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The DNA Damage Response: Making It Safe to Play with Knives

20 March 2017

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Targeting the dynamic HSP90 complex in cancer

20 March 2017

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Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression

20 March 2017

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Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

20 March 2017

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

20 March 2017

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The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy

20 March 2017

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Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response

20 March 2017

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Small-molecule drugs mimicking DNA damage: a new strategy for sensitizing tumors to radiotherapy

20 March 2017

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Trex1 prevents cell-intrinsic initiation of autoimmunity

20 March 2017

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The 67 kDa laminin receptor: structure, function and role in disease

20 March 2017

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

20 March 2017

1 reference

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

20 March 2017

1 reference

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

20 March 2017

1 reference

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Association of NASP with HSP90 in mouse spermatogenic cells: stimulation of ATPase activity and transport of linker histones into nuclei

20 March 2017

1 reference

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Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

20 March 2017

1 reference

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The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

20 March 2017

1 reference

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The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage

20 March 2017

1 reference

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A guided tour into subcellular colocalization analysis in light microscopy

20 March 2017

1 reference

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HSP90 and the chaperoning of cancer

7 April 2017

1 reference

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The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates

7 April 2017

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The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax

29 September 2017

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Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers

29 September 2017

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Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair.

29 September 2017

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Mechanisms of double-strand break repair in somatic mammalian cells

29 September 2017

1 reference

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p30 DBC is a potential regulator of tumorigenesis

29 September 2017

1 reference

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53BP1: function and mechanisms of focal recruitment

29 September 2017

1 reference

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Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

29 September 2017

1 reference

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DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship.

29 September 2017

1 reference

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Heat shock protein 90 as a drug target: some like it hot.

29 September 2017

1 reference

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EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.

29 September 2017

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Biomarkers for DNA DSB inhibitors and radiotherapy clinical trials

29 September 2017

1 reference

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The Hsp90 molecular chaperone: an open and shut case for treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?

29 September 2017

1 reference

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Inhibition of Hsp90: a multitarget approach to radiosensitization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Inhibition of hsp90 compromises the DNA damage response to radiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

DNA double-strand break repair: all's well that ends well

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Independent regulation of Hsp70 and Hsp90 chaperones by Hsp70/Hsp90-organizing protein Sti1 (Hop1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Preferential sensitization of tumor cells to radiation by heat shock protein 90 inhibitor geldanamycin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Interactions of viruses with the cellular DNA repair machinery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Involvement of cadherins 7 and 20 in mouse embryogenesis and melanocyte transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

The DNA-dependent protein kinase: the director at the end.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Human MRE11 is inactivated in mismatch repair-deficient cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Protein phosphatases regulate DNA-dependent protein kinase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Function of nucleoside triphosphate and polynucleotide in Escherichia coli recA protein-directed cleavage of phage lambda repressor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Cell surface expression of the 70-kD component of Ku, a DNA-binding nuclear autoantigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Extracellular HSP90: conquering the cell surface

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Non-parametric quantification of protein lysate arrays.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Extracellular heat shock protein-90alpha: linking hypoxia to skin cell motility and wound healing

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308794

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22270370

12 December 2020

inferred from PubMed ID database lookup

The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein, hsp90 alpha at two NH2-terminal threonine residues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22270370

12 December 2020

inferred from PubMed ID database lookup

Purification of the major mammalian heat shock proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22270370

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M111.320887

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22270370%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

2 references