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Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
title
Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells
(English)
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
main subject
3-phosphoinositide dependent protein kinase 1
1 reference
stated in
GOA release 2020-03-11
author
Beatriz Sosa-Pineda
series ordinal
5
0 references
author name string
Joby J. Westmoreland
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
Qian Wang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
Mohamed Bouzaffour
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
Suzanne J. Baker
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 October 2009
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stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
published in
Developmental Biology
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stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
volume
334
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stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
issue
1
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stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
page(s)
285–298
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stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
describes a project that uses
ImageJ
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Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2744847/fullTextXML
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inferred from PubMed Central ID database lookup
cites work
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SKAR is a specific target of S6 kinase 1 in cell growth control
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PDK1, the master regulator of AGC kinase signal transduction
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Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance
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The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.
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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
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Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains
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The two TORCs and Akt.
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Pancreatic development and disease
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Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.
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Genes, Signals, and Lineages in Pancreas Development
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Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia
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Phosphorylation of eukaryotic translation initiation factor 4E is critical for growth
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Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.
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PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression
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PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response
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27 November 2018
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas
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27 November 2018
Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells.
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PubMed Central
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The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development
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27 November 2018
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice
1 reference
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PubMed Central
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27 November 2018
Drosophila S6 kinase: a regulator of cell size
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2744847
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27 November 2018
Z/AP, a double reporter for cre-mediated recombination.
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27 November 2018
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.07.030
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7 January 2021
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
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Crossref
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7 January 2021
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19635472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Developmental biology of the pancreas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19635472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.YDBIO.2009.07.030
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
PMCID
2744847
0 references
PubMed ID
19635472
1 reference
stated in
PubMed
PubMed ID
19635472
retrieved
31 January 2017
ResearchGate publication ID
26698502
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