(Q30274624)

22 February 2018

title

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy (English)

1 reference

22 February 2018

Valosin containing protein

main subject

autophagy

0 references

1 reference

UBX domain protein 6

1 reference

Phospholipase A2 activating protein

1 reference

YOD1 deubiquitinase

1 reference

macroautophagy

1 reference

author

Michael Ehrmann

12

1 reference

22 February 2018

Hemmo H Meyer

14

1 reference

22 February 2018

author name string

Chrisovalantis Papadopoulos

1

1 reference

22 February 2018

Philipp Kirchner

2

1 reference

22 February 2018

Monika Bug

3

1 reference

22 February 2018

Daniel Grum

4

1 reference

22 February 2018

Lisa Koerver

5

1 reference

22 February 2018

Nina Schulze

6

1 reference

22 February 2018

Robert Poehler

7

1 reference

22 February 2018

Alina Dressler

8

1 reference

22 February 2018

Sven Fengler

9

1 reference

22 February 2018

Khalid Arhzaouy

10

1 reference

22 February 2018

Vanda Lux

11

1 reference

22 February 2018

Conrad C Weihl

13

1 reference

22 February 2018

language of work or name

English

0 references

publication date

17 October 2016

1 reference

22 February 2018

number of pages

16

1 reference

inferred from page(s)

published in

The EMBO Journal

1 reference

22 February 2018

volume

36

1 reference

22 February 2018

issue

2

1 reference

22 February 2018

page(s)

135-150

1 reference

22 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5242375/fullTextXML

inferred from PubMed Central ID database lookup

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3 June 2018

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3 June 2018

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Spatiotemporally controlled induction of autophagy-mediated lysosome turnover

3 June 2018

1 reference

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Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function

3 June 2018

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Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis

3 June 2018

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3 June 2018

1 reference

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VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations

3 June 2018

1 reference

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3 June 2018

1 reference

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Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

3 June 2018

1 reference

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3 June 2018

1 reference

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Roles of p97-associated deubiquitinases in protein quality control at the endoplasmic reticulum

3 June 2018

1 reference

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Ubiquitination and selective autophagy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Inflammaging: disturbed interplay between autophagy and inflammasomes

3 June 2018

1 reference

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Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking

3 June 2018

1 reference

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Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations

3 June 2018

1 reference

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3 June 2018

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The p97 ATPase associates with EEA1 to regulate the size of early endosomes

3 June 2018

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3 June 2018

1 reference

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box Proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Autophagy in mammalian development and differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Current knowledge of the pre-autophagosomal structure (PAS).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Lysosomal membrane permeabilization in cell death

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

DOA1/UFD3 plays a role in sorting ubiquitinated membrane proteins into multivesicular bodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

The roles of intracellular protein-degradation pathways in neurodegeneration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Doa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

Artificial induction of autophagy around polystyrene beads in nonphagocytic cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5242375

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27753622

12 December 2020

inferred from PubMed ID database lookup

Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27753622

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.15252/EMBJ.201695148

1 reference

22 February 2018

PMC publication ID

5242375

1 reference

22 February 2018

PubMed publication ID

27753622

1 reference

22 February 2018