(Q33408959)

PubMed publication ID

19215299

26 July 2017

title

Data-driven homology modelling of P-glycoprotein in the ATP-bound state indicates flexibility of the transmembrane domains (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

main subject

transmembrane protein

0 references

author

Gerhard Ecker

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

Thomas Stockner

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

Alexandre Bonvin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

author name string

Sjoerd J de Vries

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

Peter Chiba

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

1 February 2009

1 reference

PubMed publication ID

26 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

volume

276

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

page(s)

964-972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

Biochemistry of multidrug resistance mediated by the multidrug transporter

13 May 2020

cites work

1 reference

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Waltzing transporters and 'the dance macabre' between humans and bacteria

21 January 2018

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Multidrug resistance in cancer: role of ATP-dependent transporters

21 January 2018

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Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use.

21 January 2018

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ABC Transporters: From Microorganisms to Man

21 January 2018

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Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

21 January 2018

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Structure of a bacterial multidrug ABC transporter

21 January 2018

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Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP

21 January 2018

1 reference

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Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

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Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein

21 January 2018

1 reference

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Structural insights into P-glycoprotein (ABCB1) by small angle X-ray scattering and electron crystallography.

21 January 2018

1 reference

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Multidrug transport by the ABC transporter Sav1866 from Staphylococcus aureus

21 January 2018

1 reference

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Identification of putative binding sites of P-glycoprotein based on its homology model

21 January 2018

1 reference

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Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)

21 January 2018

1 reference

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Val133 and Cys137 in transmembrane segment 2 are close to Arg935 and Gly939 in transmembrane segment 11 of human P-glycoprotein

21 January 2018

1 reference

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ATP hydrolysis promotes interactions between the extracellular ends of transmembrane segments 1 and 11 of human multidrug resistance P-glycoprotein.

21 January 2018

1 reference

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Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments

21 January 2018

1 reference

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Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Disulfide cross-linking analysis shows that transmembrane segments 5 and 8 of human P-glycoprotein are close together on the cytoplasmic side of the membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Membrane protein dynamics versus environment: simulations of OmpA in a micelle and in a bilayer.

21 January 2018

1 reference

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The role of dynamics in enzyme activity

21 January 2018

1 reference

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The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Cytosolic region of TM6 in P-glycoprotein: topographical analysis and functional perturbation by site directed labeling

21 January 2018

1 reference

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Structure and mechanism of ABC transporter proteins.

21 January 2018

1 reference

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The lateral pressure profile in membranes: a physical mechanism of general anesthesia

21 January 2018

1 reference

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Mesoscopic undulations and thickness fluctuations in lipid bilayers from molecular dynamics simulations

21 January 2018

1 reference

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Structural basis of energy transduction in the transport cycle of MsbA.

21 January 2018

1 reference

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Solvation energy in protein folding and binding

21 January 2018

1 reference

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Diversity of protein-protein interactions

21 January 2018

1 reference

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Permanent Activation of the Human P-glycoprotein by Covalent Modification of a Residue in the Drug-binding Site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Evaluation of comparative protein modeling by MODELLER

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

GROMACS: fast, flexible, and free

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Recognition of errors in three-dimensional structures of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Can correct protein models be identified?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

Drug-stimulated ATPase Activity of Human P-glycoprotein Requires Movement between Transmembrane Segments 6 and 12

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06832.X

P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19215299

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The protein state of matter

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19215299

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1742-4658.2008.06832.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6422310&resulttype=core&format=json

13 May 2020

PubMed publication ID

19215299

1 reference