(Q33730568)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

Inferring fitness landscapes by regression produces biased estimates of epistasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

language of work or name

English

0 references

publication date

19 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

18 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

E2301-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

Should evolutionary geneticists worry about higher-order epistasis?

18 March 2020

cites work

1 reference

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Comprehensive experimental fitness landscape and evolutionary network for small RNA.

21 June 2018

1 reference

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Experiments on the role of deleterious mutations as stepping stones in adaptive evolution

21 June 2018

1 reference

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Capturing the mutational landscape of the beta-lactamase TEM-1.

21 June 2018

1 reference

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Genotype to phenotype mapping and the fitness landscape of the E. coli lac promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

The spatial architecture of protein function and adaptation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Exploring the complexity of the HIV-1 fitness landscape

21 June 2018

1 reference

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Predictability of evolutionary trajectories in fitness landscapes

21 June 2018

1 reference

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21 June 2018

ViennaRNA Package 2.0

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Quantifying selection acting on a complex trait using allele frequency time series data.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Distinguishing driver and passenger mutations in an evolutionary history categorized by interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Epistasis between beneficial mutations and the phenotype-to-fitness Map for a ssDNA virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Diminishing returns epistasis among beneficial mutations decelerates adaptation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Deep mutational scanning: assessing protein function on a massive scale

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscape

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Experimental illumination of a fitness landscape

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Second-order selection for evolvability in a large Escherichia coli population

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Prevalence of epistasis in the evolution of influenza A surface proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Pervasive Cryptic Epistasis in Molecular Evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Rapid Construction of Empirical RNA Fitness Landscapes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

High-resolution mapping of protein sequence-function relationships

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

The dynamics of adaptation on correlated fitness landscapes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Positive epistasis drives the acquisition of multidrug resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Revealing evolutionary pathways by fitness landscape reconstruction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

In the light of directed evolution: pathways of adaptive protein evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Protein dynamism and evolvability.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

The rate at which asexual populations cross fitness valleys

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Directed enzyme evolution: climbing fitness peaks one amino acid at a time

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Constructing and analyzing the fitness landscape of an experimental evolutionary process

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Empirical fitness landscapes reveal accessible evolutionary paths

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Darwinian evolution can follow only very few mutational paths to fitter proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Perspective: Sign epistasis and genetic constraint on evolutionary trajectories

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Diverse evolutionary trajectories characterize a community of RNA-cleaving deoxyribozymes: a case study into the population dynamics of in vitro selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

The genetic theory of adaptation: a brief history

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Stochastic tunnels in evolutionary dynamics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Evolution by small steps and rugged landscapes in the RNA virus phi6

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Protein evolution on partially correlated landscapes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Experimental investigation of an RNA sequence space

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Towards a general theory of adaptive walks on rugged landscapes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Protein evolution on rugged landscapes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

The NK model of rugged fitness landscapes and its application to maturation of the immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Environmental change exposes beneficial epistatic interactions in a catalytic RNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050575

Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Effects of selective neutrality on the evolution of molecular species

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

How Mutational Networks Shape Evolution: Lessons from RNA Models

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Equally parsimonious pathways through an RNA sequence space are not equally likely.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Negative epistasis between beneficial mutations in an evolving bacterial population

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Selection biases the prevalence and type of epistasis along adaptive trajectories

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Random field models for fitness landscapes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Exact results for amplitude spectra of fitness landscapes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Epistatic interactions determine the mutational pathways and coexistence of lineages in clonal Escherichia coli populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Rapid evolutionary escape by large populations from local fitness peaks is likely in nature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400849111

Fitness epistasis among 6 biosynthetic loci in the budding yeast Saccharomyces cerevisiae

21 January 2018

1 reference

12 December 2020

Modeling genetic architecture: a multilinear theory of gene interaction

1 reference

12 December 2020

Rapid in vivo exploration of a 5S rRNA neutral network

1 reference

12 December 2020

Evolution in a rugged fitness landscape

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1400849111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

0 references

1 reference

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

24843135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json