(Q33892839)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

review article

1 reference

title

Regulation of p53 stability and activity in response to genotoxic stress (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

M S Colman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

C A Afshari

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

J C Barrett

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 April 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

179-188

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

2-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

Three distinct signalling responses by murine fibroblasts to genotoxic stress

5 November 2019

cites work

1 reference

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7 January 2021

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7 January 2021

p53 gene mutation: software and database

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

A model for p53-induced apoptosis

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7 January 2021

Abnormal expression or mutation of TP53 and HPV in vulvar cancer

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7 January 2021

p53 and genetic susceptibility to cervical cancer

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7 January 2021

p53 polymorphism and risk of cervical cancer

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7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

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7 January 2021

The role of ATM in DNA damage responses and cancer

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7 January 2021

Mdm2: keeping p53 under control

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7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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7 January 2021

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

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7 January 2021

Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.

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7 January 2021

The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo

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7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

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7 January 2021

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

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7 January 2021

Regulation of p53 function and stability by phosphorylation

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7 January 2021

DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation

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7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

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7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

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7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

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7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

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7 January 2021

c-Abl neutralizes the inhibitory effect of Mdm2 on p53.

1 reference

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases

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7 January 2021

Proteolytic cleavage of the mdm2 oncoprotein during apoptosis

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7 January 2021

A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells

1 reference

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7 January 2021

Activation of an MDM2-specific caspase by p53 in the absence of apoptosis

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7 January 2021

MDM2 interacts with MDMX through their RING finger domains

1 reference

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

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7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

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7 January 2021

The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase

1 reference

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7 January 2021

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

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7 January 2021

JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases

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7 January 2021

Stabilization and activation of p53 are regulated independently by different phosphorylation events

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7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

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7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

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7 January 2021

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

1 reference

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7 January 2021

Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

1 reference

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7 January 2021

DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site

1 reference

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7 January 2021

The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro

1 reference

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7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

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7 January 2021

Interaction of p53 with the human Rad51 protein

1 reference

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7 January 2021

The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

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7 January 2021

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

1 reference

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7 January 2021

Identification of redox/repair protein Ref-1 as a potent activator of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900035-1

7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

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7 January 2021

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900035-1

7 January 2021

p53 regulates a G2 checkpoint through cyclin B1

1 reference

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7 January 2021

Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis

1 reference

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7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

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7 January 2021

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

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7 January 2021

Reactive oxygen species are downstream mediators of p53-dependent apoptosis

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7 January 2021

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900035-1

7 January 2021

Transcriptional activation of the human glutathione peroxidase promoter by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900035-1

7 January 2021

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900035-1

7 January 2021

Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2800%2900035-1

7 January 2021

Involvement of p85 in p53-dependent apoptotic response to oxidative stress

1 reference

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7 January 2021

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

1 reference

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7 January 2021

Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers

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7 January 2021

PIK3CA is implicated as an oncogene in ovarian cancer.

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7 January 2021

10.1016/S1383-5742(00)00035-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10767629%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference