(Q34375148)

English

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

crystal structure

1 reference

based on heuristic

inferred from title

10

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

object named as

James A Irving

4

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object named as

Ashley M Buckle

2

0 references

James C Whisstock

object named as

James C Whisstock

11

0 references

object named as

Arthur M Lesk

8

0 references

Stephen P Bottomley

9

object named as

Stephen P Bottomley

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Kate F Fulton

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Lisa D Cabrita

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Rebecca E Butcher

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Ian Smith

6

1 reference

Europe PubMed Central

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1 August 2017

Shane Reeve

7

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Europe PubMed Central

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1 August 2017

language of work or name

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publication date

7 December 2004

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Europe PubMed Central

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1 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

1 August 2017

280

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Europe PubMed Central

PubMed publication ID

1 August 2017

9

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Europe PubMed Central

PubMed publication ID

1 August 2017

8435-8442

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Evolutionary families of peptidase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The evolution of enzyme specificity in Fasciola spp.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Plakalbumin, alpha 1-antitrypsin, antithrombin and the mechanism of inflammatory thrombosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Different conformational changes within the F-helix occur during serpin folding, polymerization, and proteinase inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Serpin tertiary structure transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.

1 reference

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21 January 2018

The anticoagulant activation of antithrombin by heparin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Probing the unfolding pathway of alpha1-antitrypsin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The Z type variation of human alpha 1-antitrypsin causes a protein folding defect

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Serpinopathies and the conformational dementias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Promiscuous beta-strand interactions and the conformational diseases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Alpha1-antitrypsin deficiency--a model for conformational diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The mechanism of alpha 1-antitrypsin polymerization probed by fluorescence spectroscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Serpins in prokaryotes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Crystal structure of the hyperthermophilic inorganic pyrophosphatase from the archaeon Pyrococcus horikoshii

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Crystal structure of a heat-resilient phytase from Aspergillus fumigatus, carrying a phosphorylated histidine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Protein thermal stability: hydrogen bonds or internal packing?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The crystal structure of a hyperthermophilic archaeal TATA-box binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Comparative thermodynamic elucidation of the structural stability of thermophilic proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Structural basis for the extreme thermostability of D-glyceraldehyde-3-phosphate dehydrogenase from Thermotoga maritima: analysis based on homology modelling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Determination and analysis of urea and guanidine hydrochloride denaturation curves

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

A graphical user interface to the CCP4 program suite

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Ligand Depot: a data warehouse for ligands bound to macromolecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Homology modeling, model and software evaluation: three related resources

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Occluded molecular surface: analysis of protein packing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Visualizing and quantifying molecular goodness-of-fit: small-probe contact dots with explicit hydrogen atoms

1 reference

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21 January 2018

What do dysfunctional serpins tell us about molecular mobility and disease?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

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21 January 2018

Crystal structure of the Escherichia coli peptide methionine sulphoxide reductase at 1.9 A resolution

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21 January 2018

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining

1 reference

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21 January 2018

Targeting a surface cavity of alpha 1-antitrypsin to prevent conformational disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Engineering thermostability in serine protease inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

Concerted regulation of inhibitory activity of alpha 1-antitrypsin by the native strain distributed throughout the molecule

1 reference

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21 January 2018

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

1 reference

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21 January 2018

Stabilization of GroEL minichaperones by core and surface mutations

1 reference

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21 January 2018

How do proteins avoid becoming too stable? Biophysical studies into metastable proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

The 1.5 Å Crystal Structure of a Prokaryote Serpin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410206200

21 January 2018

A Kinetic Mechanism for the Polymerization of α1-Antitrypsin

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M410206200

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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