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Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.
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3003696
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6 February 2020
title
Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells
(English)
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3003696
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6 February 2020
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Alexander Loewer
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1
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6 February 2020
Eric Batchelor
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3003696
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6 February 2020
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Giorgio Gaglia
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6 February 2020
Galit Lahav
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4
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6 February 2020
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1 July 2010
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6 February 2020
published in
Cell
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6 February 2020
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142
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6 February 2020
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1
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6 February 2020
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89-100
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6 February 2020
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PubMed Central
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6 July 2018
Blinded by the Light: The Growing Complexity of p53
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6 July 2018
Distinct mechanisms act in concert to mediate cell cycle arrest
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6 July 2018
ATM and Chk2 kinase target the p53 cofactor Strap
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6 July 2018
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression
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Acetylation is indispensable for p53 activation
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Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
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Transcriptional control of human p53-regulated genes
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Regulation of DNA repair throughout the cell cycle
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An acetylation switch in p53 mediates holo-TFIID recruitment
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The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop
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6 July 2018
Modulation of p53 function by SET8-mediated methylation at lysine 382
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Methylation-acetylation interplay activates p53 in response to DNA damage
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6 July 2018
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6 July 2018
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6 July 2018
Site-specific acetylation of p53 directs selective transcription complex assembly.
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6 July 2018
Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants
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6 July 2018
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
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6 July 2018
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6 July 2018
Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins
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6 July 2018
Oscillations and variability in the p53 system
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6 July 2018
The antioxidant function of the p53 tumor suppressor
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6 July 2018
Phosphorylation of histone H2AX at M phase in human cells without DNA damage response
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6 July 2018
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6 July 2018
Histone deacetylase inhibitors differentially stabilize acetylated p53 and induce cell cycle arrest or apoptosis in prostate cancer cells.
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6 July 2018
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6 July 2018
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6 July 2018
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6 July 2018
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
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6 July 2018
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6 July 2018
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6 July 2018
The Coherent Feedforward Loop Serves as a Sign-sensitive Delay Element in Transcription Networks
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6 July 2018
A quantitative description of membrane current and its application to conduction and excitation in nerve
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6 July 2018
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
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6 July 2018
The p53-Mdm2 module and the ubiquitin system.
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6 July 2018
A system for stable expression of short interfering RNAs in mammalian cells
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6 July 2018
Binding to the naturally occurring double p53 binding site of the Mdm2 promoter alleviates the requirement for p53 C-terminal activation
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6 July 2018
Surfing the p53 network
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6 July 2018
Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study
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6 July 2018
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
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6 July 2018
Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest
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6 July 2018
The p53-mdm-2 autoregulatory feedback loop
1 reference
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6 July 2018
WAF1, a potential mediator of p53 tumor suppression
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6 July 2018
Abnormal response of ataxia-telangiectasia cells to agents that break the deoxyribose moiety of DNA via a targeted free radical mechanism.
1 reference
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6 July 2018
Cell cycle synchronization at the G2/M phase border by reversible inhibition of CDK1.
1 reference
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27 October 2018
Stable suppression of tumorigenicity by virus-mediated RNA interference
1 reference
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27 October 2018
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20598361
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20598361
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELL.2010.05.031
1 reference
stated in
Europe PubMed Central
PMC publication ID
3003696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20598361%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PMC publication ID
3003696
1 reference
stated in
Europe PubMed Central
PMC publication ID
3003696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20598361%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PubMed publication ID
20598361
1 reference
stated in
Europe PubMed Central
PMC publication ID
3003696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20598361%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
ResearchGate publication ID
45089499
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