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Replication licensing and the DNA damage checkpoint.
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1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Replication licensing and the DNA damage checkpoint
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
main subject
DNA damage
0 references
author
Jeanette Gowen Cook
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author name string
Jeanette Gowen Cook
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
19482602
retrieved
2 August 2017
publication date
1 June 2009
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Frontiers in Bioscience
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
14
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
5013-5030
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
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Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.
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Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.
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The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
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The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses
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Chk1 regulates the density of active replication origins during the vertebrate S phase.
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ATM and ATR: components of an integrated circuit
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Cdc7-Dbf4 and the human S checkpoint response to UVC
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Specific role of Chk1 phosphorylations in cell survival and checkpoint activation
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7 July 2018
The APC/C inhibitor, Emi1, is essential for prevention of rereplication
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Centrosomal localization of DNA damage checkpoint proteins
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7 July 2018
Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.
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CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast
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A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus
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DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1
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7 July 2018
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
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The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism
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7 July 2018
L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage
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7 July 2018
Surviving the breakup: the DNA damage checkpoint.
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7 July 2018
Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
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7 July 2018
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress.
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7 July 2018
Regulating the licensing of DNA replication origins in metazoa
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7 July 2018
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks
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7 July 2018
Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation
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7 July 2018
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
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7 July 2018
The functional role of Cdc6 in S-G2/M in mammalian cells
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7 July 2018
PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination
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7 July 2018
An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage
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7 July 2018
Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase
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7 July 2018
Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.
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7 July 2018
The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation
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7 July 2018
BH3-ligand regulates access of MCL-1 to its E3 ligase
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7 July 2018
Right place, right time, and only once: replication initiation in metazoans
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7 July 2018
Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe
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7 July 2018
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis
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7 July 2018
Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A.
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7 July 2018
p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation
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7 July 2018
Geminin regulates neuronal differentiation by antagonizing Brg1 activity
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7 July 2018
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
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7 July 2018
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor
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7 July 2018
Preventing re-replication of chromosomal DNA.
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7 July 2018
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.
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7 July 2018
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
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7 July 2018
Characterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones
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7 July 2018
Lack of PTEN sequesters CHK1 and initiates genetic instability.
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7 July 2018
Origin recognition and the chromosome cycle
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7 July 2018
Geminin-Cdt1 balance is critical for genetic stability
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7 July 2018
Over-expression of human UREB1 in colorectal cancer: HECT domain of human UREB1 inhibits the activity of tumor suppressor p53 protein
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7 July 2018
Cell-cycle checkpoints and cancer
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7 July 2018
Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage
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7 July 2018
Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro
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7 July 2018
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
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PubMed Central
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7 July 2018
Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses
1 reference
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PubMed Central
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7 July 2018
Regulation of early events in chromosome replication
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PubMed Central
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7 July 2018
ORC-associated replication factors as biomarkers for cancer.
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7 July 2018
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
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PubMed Central
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7 July 2018
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
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PubMed Central
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7 July 2018
Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines
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PubMed Central
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7 July 2018
Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The PCNA-RFC families of DNA clamps and clamp loaders
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Loss of Geminin induces rereplication in the presence of functional p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Dynamics of pre-replication complex proteins during the cell division cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Direct interaction of geminin and Six3 in eye development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The 'ORC cycle': a novel pathway for regulating eukaryotic DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
A p53-dependent checkpoint pathway prevents rereplication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Identification of MCM4 as a Target of the DNA Replication Block Checkpoint System
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Control of DNA replication licensing in a cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Control of DNA replication and chromosome ploidy by geminin and cyclin A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Oncogenic potential of the DNA replication licensing protein CDT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Mammalian nuclei become licensed for DNA replication during late telophase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
ATR and ATRIP: partners in checkpoint signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cell cycle checkpoint signaling through the ATM and ATR kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Chromatin-bound Cdc6 persists in S and G2 phases in human cells, while soluble Cdc6 is destroyed in a cyclin A-cdk2 dependent process.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cell cycle- and chromatin binding state-dependent phosphorylation of human MCM heterohexameric complexes. A role for cdc2 kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Geminin, an inhibitor of DNA replication, is degraded during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Expression, nuclear localization and interactions of human MCM/P1 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Binding of human minichromosome maintenance proteins with histone H3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Atm-deficient mice: a paradigm of ataxia telangiectasia
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Expression, phosphorylation and nuclear localization of the human P1 protein, a homologue of the yeast Mcm 3 replication protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
7 July 2018
Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Control of the Cdc6 replication licensing factor in metazoa: the role of nuclear export and the CUL4 ubiquitin ligase.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Checkpoint regulation of replication dynamics in UV-irradiated human cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
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27 October 2018
One ring to rule them all? Another cellular responsibility for PCNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
CDK phosphorylation inhibits the DNA-binding and ATP-hydrolysis activities of the Drosophila origin recognition complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
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27 October 2018
Control of DNA replication and its potential clinical exploitation.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Regulation of Geminin and Cdt1 expression by E2F transcription factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Proteasome Involvement in the Repair of DNA Double-Strand Breaks
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
27 October 2018
Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032801
retrieved
9 December 2018
Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19482602
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The transcriptional program following p53 activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19482602
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19482602
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2741/3584
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PMCID
3032801
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed ID
19482602
1 reference
stated in
Europe PubMed Central
PMCID
3032801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
ResearchGate publication ID
26253525
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