(Q34728229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Targeting Gli transcription activation by small molecule suppresses tumor growth (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

G Bosco-Clément

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

F Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Z Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

H-M Zhou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

H Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

I Mikami

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

T Hirata

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

A Yagui-Beltran

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

N Lui

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

H T Do

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

T Cheng

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

H-H Tseng

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

H Choi

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

I-J Kim

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

D Yue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

C Wang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Q Zheng

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

N Fujii

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

M Mann

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

D M Jablons

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

B He

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

20 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

2087-2097

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2013.164

1 March 2020

exact match

0 references

cites work

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1 reference

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Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.

7 July 2018

1 reference

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New Hedgehog/GLI signaling inhibitors from Excoecaria agallocha.

7 July 2018

1 reference

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New hedgehog/GLI-signaling inhibitors from Adenium obesum.

7 July 2018

1 reference

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Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance

7 July 2018

1 reference

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Clinical experience with Hedgehog pathway inhibitors

7 July 2018

1 reference

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EMX2 is epigenetically silenced and suppresses growth in human lung cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Targeting Hedgehog--a cancer stem cell pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

7 July 2018

1 reference

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Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926)

7 July 2018

1 reference

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

7 July 2018

1 reference

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Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

7 July 2018

1 reference

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Signaling cross-talk between TGF-beta/BMP and other pathways

7 July 2018

1 reference

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Hedgehog: functions and mechanisms

7 July 2018

1 reference

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A paracrine requirement for hedgehog signalling in cancer

7 July 2018

1 reference

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Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

The Gli code: an information nexus regulating cell fate, stemness and cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

7 July 2018

1 reference

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Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Hedgehog/Ras interactions regulate early stages of pancreatic cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Walleye dermal sarcoma virus retroviral cyclin directly contacts TAF9.

7 July 2018

1 reference

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Small organic molecules that modulate gene transcription

7 July 2018

1 reference

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Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling

7 July 2018

1 reference

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Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

7 July 2018

1 reference

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Communicating with Hedgehogs

7 July 2018

1 reference

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Core promoter binding by histone-like TAF complexes

7 July 2018

1 reference

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

7 July 2018

1 reference

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Cloning and characterization of the promoter of human Wnt inhibitory factor-1.

7 July 2018

1 reference

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A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Transducing the hedgehog signal

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Divergent hTAFII31-binding motifs hidden in activation domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Histone-like TAFs within the PCAF histone acetylase complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

A histone octamer-like structure within TFIID

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Characterization of adenovirus particles made by deletion mutants lacking the fiber gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947751

Wnt signals are targets and mediators of Gli function.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.164

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.164

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.164

GLI activates transcription through a herpes simplex viral protein 16-like activation domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.164

A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.164

21 January 2018

Identifiers

DOI

10.1038/ONC.2013.164

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686308%20AND%20SRC:MED&resulttype=core&format=json