(Q34982168)

5 August 2017

title

The molecular basis for the chemical denaturation of proteins by urea (English)

1 reference

5 August 2017

1 reference

2

Valerie Daggett

1 reference

5 August 2017

Brian J. Bennion

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12702764

25 December 2023

language of work or name

English

0 references

publication date

17 April 2003

1 reference

5 August 2017

number of pages

6

1 reference

full work available at URL

inferred from page(s)

http://www.pnas.org/content/100/9/5142.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12702764

https://europepmc.org/articles/PMC154312

25 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12702764

https://europepmc.org/articles/PMC154312?pdf=render

25 December 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12702764

https://doi.org/10.1073/pnas.0930122100

25 December 2023

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12702764

https://pnas.org/doi/pdf/10.1073/pnas.0930122100

25 December 2023

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0930122100

Proceedings of the National Academy of Sciences of the United States of America

25 December 2023

published in

1 reference

5 August 2017

volume

100

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5 August 2017

issue

9

1 reference

5 August 2017

page(s)

5142-5147

1 reference

Raster3D Version 2.0. A program for photorealistic molecular graphics

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Some factors in the interpretation of protein denaturation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Thermal and urea-induced unfolding of the marginally stable lac repressor DNA-binding domain: a model system for analysis of solute effects on protein processes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Thermodynamic binding and site occupancy in the light of the Schellman exchange concept

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Protein-solvent preferential interactions, protein hydration, and the modulation of biochemical reactions by solvent components

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Protein folding and unfolding at atomic resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

The molecular mechanism of stabilization of proteins by TMAO and its ability to counteract the effects of urea

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Thermodynamics of interactions of urea and guanidinium salts with protein surface: relationship between solute effects on protein processes and changes in water-accessible surface area

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Protein folding from a highly disordered denatured state: the folding pathway of chymotrypsin inhibitor 2 at atomic resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Synergy between simulation and experiment in describing the energy landscape of protein folding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

A naturally occurring protective system in urea-rich cells: mechanism of osmolyte protection of proteins against urea denaturation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Molecular dynamics simulations of the unfolding of barnase in water and 8 M aqueous urea

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

VMD: visual molecular dynamics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Identification and characterization of the unfolding transition state of chymotrypsin inhibitor 2 by molecular dynamics simulations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

The control of protein stability and association by weak interactions with water: how do solvents affect these processes?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Interaction of urea with an unfolded protein. The DNA-binding domain of the 434-repressor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Molecular dynamics simulations of protein unfolding and limited refolding: characterization of partially unfolded states of ubiquitin in 60% methanol and in water

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Protein denaturation. C. Theoretical models for the mechanism of denaturation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Determination and analysis of urea and guanidine hydrochloride denaturation curves

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Solvent denaturation and stabilization of globular proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Water as ligand: preferential binding and exclusion of denaturants in protein unfolding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

The dominant interaction between peptide and urea is electrostatic in nature: a molecular dynamics simulation study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Generalized derivation of an exact relationship linking different coefficients that characterize thermodynamic effects of preferential interactions

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Increasing temperature accelerates protein unfolding without changing the pathway of unfolding

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Fifty years of solvent denaturation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Control of protein stability and reactions by weakly interacting cosolvents: the simplicity of the complicated

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Structure of the transition state for folding of a protein derived from experiment and simulation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154312

Mechanism of protein salting in and salting out by divalent cation salts: balance between hydration and salt binding

26 October 2018

1 reference

12 December 2020

THE EFFECT OF COMPOUNDS OF THE UREA-GUANIDINIUM CLASS ON THE ACTIVITY COEFFICIENT OF ACETYLTETRAGLYCINE ETHYL ESTER AND RELATED COMPOUNDS

1 reference

12 December 2020

Protein interactions with urea and guanidinium chloride. A calorimetric study

1 reference

12 December 2020

Urea effects on protein stability: hydrogen bonding and the hydrophobic effect

1 reference

12 December 2020

Structural details of urea binding to barnase: a molecular dynamics analysis

1 reference

12 December 2020

Protein stabilization and destabilization by guanidinium salts

1 reference

12 December 2020

The unfolding of beta-lactoglobulin at pH 3 by urea, formamide, and other organic substances

1 reference

12 December 2020

Selective binding and solvent denaturation

1 reference

12 December 2020

Rationalization of the Enantioselectivity of Subtilisin in DMF

series ordinal

25

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0930122100

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

25 December 2023

series ordinal

44

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0930122100

25 December 2023

Identifiers

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference