(Q35049064)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

review article

1 reference

title

Caspase inhibitors as anti-inflammatory and antiapoptotic agents (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

author name string

Piotr P Graczyk

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

publication date

1 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

Progress in medicinal chemistry

16 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

page(s)

1-72

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

Families of cysteine peptidases.

16 December 2019

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Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases

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ERICE, a novel FLICE-activatable caspase

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Caspase-14 is a novel developmentally regulated protease

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7 January 2021

Identification of a new caspase homologue: caspase-14

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7 January 2021

A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE)

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7 January 2021

In vitro and in vivo studies of ICE inhibitors

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7 January 2021

Apoptosis in development

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7 January 2021

Apoptosis and the nervous system

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7 January 2021

Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites

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7 January 2021

Is apoptosis key in Alzheimer's disease?

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7 January 2021

Recent advances in Huntington's disease

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7 January 2021

Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

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7 January 2021

Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons--a possible novel pathogenetic mechanism in Parkinson's disease.

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7 January 2021

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

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7 January 2021

Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

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7 January 2021

Apoptosis in neurological disease

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7 January 2021

Apoptosis modulators in the therapy of neurodegenerative diseases

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7 January 2021

Apoptosis in the nervous system

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7 January 2021

Apoptotic and antiapoptotic mechanisms in stroke.

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Apoptosis after traumatic human spinal cord injury

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7 January 2021

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7 January 2021

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7 January 2021

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

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7 January 2021

Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo

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7 January 2021

Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia.

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7 January 2021

Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus.

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7 January 2021

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

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7 January 2021

Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat.

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7 January 2021

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

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7 January 2021

The role of programmed cell death as an emerging new concept for the pathogenesis of autoimmune diseases

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7 January 2021

Co-localization of the cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat

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7 January 2021

Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis

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7 January 2021

HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas upregulation

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7 January 2021

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7 January 2021

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7 January 2021

Stroke-damaged neurons may commit cellular suicide

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7 January 2021

Mechanisms of cell death in hypoxia/reoxygenation injury

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7 January 2021

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

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7 January 2021

An alternative, nonapoptotic form of programmed cell death

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Neuroprotection by the inhibition of apoptosis

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7 January 2021

From bench to clinic with apoptosis-based therapeutic agents

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7 January 2021

Caspases: key mediators of apoptosis

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7 January 2021

Caspase structure, proteolytic substrates, and function during apoptotic cell death

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7 January 2021

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Caspases in apoptotic death

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7 January 2021

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7 January 2021

Recent advances on neuronal caspases in development and neurodegeneration

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7 January 2021

Caspases as treatment targets in stroke and neurodegenerative diseases

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7 January 2021

Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches.

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7 January 2021

Chemical-induced apoptotic cell death in tomato cells: involvement of caspase-like proteases

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7 January 2021

Caspase-like protease involvement in the control of plant cell death

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7 January 2021

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

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7 January 2021

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

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7 January 2021

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

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Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

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7 January 2021

Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice

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7 January 2021

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7 January 2021

A proinflammatory role for IL-18 in rheumatoid arthritis

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7 January 2021

Interleukin-18, rheumatoid arthritis, and tissue destruction

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7 January 2021

Pathophysiological roles of interleukin-18 in inflammatory liver diseases

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7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

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7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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7 January 2021

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

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7 January 2021

Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein.

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7 January 2021

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

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7 January 2021

Contribution of the ICE family to neurodegeneration

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7 January 2021

Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage

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7 January 2021

Involvement of caspase-1 proteases in hypoxic brain injury. effects of their inhibitors in developing neurons

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7 January 2021

Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary study

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7 January 2021

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

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7 January 2021

Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade

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7 January 2021

Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity

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7 January 2021

Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons

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7 January 2021

Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1beta and interleukin-18

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7 January 2021

Investigation of the expression of IL-1beta converting enzyme and apoptosis in normal and inflammatory bowel disease (IBD) mucosal macrophages

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7 January 2021

Apoptosis as a trigger of inflammation in Shigella-induced cell death

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7 January 2021

Increased interleukin-1beta converting enzyme expression and activity in Alzheimer disease

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7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

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7 January 2021

Defects in regulation of apoptosis in caspase-2-deficient mice

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7 January 2021

Caspase-2 mediates neuronal cell death induced by beta-amyloid

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7 January 2021

Need for caspase-2 in apoptosis of growth-factor-deprived PC12 cells

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7 January 2021

Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)-like activity

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7 January 2021

Caspase inhibitors attenuate oxyhemoglobin-induced apoptosis in endothelial cells

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7 January 2021

HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism

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7 January 2021

Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis

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7 January 2021

Caspases -2, -3, -6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis.

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7 January 2021

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

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7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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7 January 2021

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury.

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7 January 2021

Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury.

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7 January 2021

Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells

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7 January 2021

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

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7 January 2021

Amyloid beta-protein induces necrotic cell death mediated by ICE cascade in PC12 cells

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7 January 2021

Caspase-3 activation by beta-amyloid and prion protein peptides is independent from their neurotoxic effect

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Requirement of the caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Activation of CPP32 during apoptosis of neurons and astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Activation of caspase-3 and apoptosis in cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Induction of hydrogen peroxide production and Bax expression by caspase-3(-like) proteases in tyrosine kinase inhibitor-induced apoptosis in human small cell lung carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The dominant role of CPP32 subfamily in fas-mediated hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Change in caspase-3-like protease in the liver and plasma during rat liver regeneration following partial hepatectomy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Ischemic preconditioning protects the mouse liver by inhibition of apoptosis through a caspase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase inhibitors block the retinal ganglion cell death following optic nerve transection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Involvement of caspase-4(-like) protease in Fas-mediated apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptosis in polycystic kidney disease: involvement of caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase 8: the killer you can't live without.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Autoimmune lymphoproliferative syndrome, a disorder of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The role of the Caspase family of cysteine proteases in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Group B Streptococcus induces apoptosis in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Heat Shock Protein 70 Inhibits Caspase-Dependent and -Independent Apoptosis in Jurkat T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Differential induction of interleukin-12, interleukin-18, and interleukin-1beta converting enzyme mRNA in experimental autoimmune encephalomyelitis of the Lewis rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Expression of interleukin-1 beta converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Up-regulation of the Nedd2 gene encoding an ICE/Ced-3-like cysteine protease in the gerbil brain after transient global ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons In vivo: A single-cell analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Differential changes of bax, caspase-3 and p21 mRNA expression after transient focal brain ischemia in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Expression of redox factor-1, p53-activated gene 608 and caspase-3 messenger RNAs following repeated unilateral common carotid artery occlusion in gerbils--relationship to delayed cell injury and secondary failure of energy state

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-3 is activated following axotomy of neonatal facial motoneurons and caspase-3 gene deletion delays axotomy-induced cell death in rodents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Rapid upregulation of caspase-3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Fas receptor and neuronal cell death after spinal cord ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Detection of pro-caspase-3 in cytosol and mitochondria of various tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Transducing signals of life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The proteolytic procaspase activation network: an in vitro analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

ICEBERG: a novel inhibitor of interleukin-1beta generation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase activation without death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase activation: the induced-proximity model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Autoproteolytic activation of pro-caspases by oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The hepatitis B virus HBx protein inhibits caspase 3 activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptosis. Death by crowd control

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cytochrome c binding to Apaf-1: the effects of dATP and ionic strength

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Activation of caspases triggered by cytochrome c in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-9 can be activated without proteolytic processing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Two Different Proteases Are Involved in the Proteolysis of Lamin during Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Changes in p21WAF1, pRb, Mdm-2, Bax and Bcl-2 expression in cervical cancer cell lines transfected with a p53 expressing adenovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspases disrupt the nuclear-cytoplasmic barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Mechanisms of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptotic pathways: the roads to ruin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Bcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Role of multiple cellular proteases in the execution of programmed cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Activation of CPP32-like proteases is not sufficient to trigger apoptosis: inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Chemotherapeutic drug activation of the AP24 protease in apoptosis: requirement for caspase 3-like-proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Control of programmed cell death by the baculovirus genes p35 and iap.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Prevention of apoptosis by a baculovirus gene during infection of insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Baculovirus p35 and Z-VAD-fmk inhibit thapsigargin-induced apoptosis of breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Expression of the baculovirus p35 gene inhibits mammalian neural cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Need for caspases in apoptosis of trophic factor-deprived PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Baculovirus P35 protein does not inhibit caspase-9 in a cell-free system of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase inhibitor P35 and inhibitor of apoptosis Op-IAP block in vivo proteolytic activation of an effector caspase at different steps

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The iap genes: unique arbitrators of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A human IAP-family gene, apollon, expressed in human brain cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Livin, a novel inhibitor of apoptosis protein family member

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of interleukin 1 beta-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The BIR motifs mediate dominant interference and oligomerization of inhibitor of apoptosis Op-IAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A single BIR domain of XIAP sufficient for inhibiting caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Evolutionary conservation of apoptosis mechanisms: lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of human caspases by peptide-based and macromolecular inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Prevention of vertebrate neuronal death by the crmA gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Crystal structure of the apoptotic suppressor CrmA in its cleaved form

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Serpins and regulation of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric oxide inhibits Fas-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric oxide prevents tumor necrosis factor alpha-induced rat hepatocyte apoptosis by the interruption of mitochondrial apoptotic signaling through S-nitrosylation of caspase-8.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Effects of redox-related congeners of NO on apoptosis and caspase-3 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric Oxide Inhibits Caspase-3 byS-Nitrosationin Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric oxide and its role in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of endogenous nitric oxide synthase potentiates ischemia-reperfusion-induced myocardial apoptosis via a caspase-3 dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

S-nitrosylation regulates apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Molecular mechanisms of apoptosis in HL-60 cells induced by a nitric oxide-releasing compound

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

N-nitrosoanilines: a new class of caspase-3 inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

IL-1 beta converting enzyme is a target for nitric oxide-releasing aspirin: new insights in the antiinflammatory mechanism of nitric oxide-releasing nonsteroidal antiinflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Depletion of intracellular zinc induces protein synthesis-dependent neuronal apoptosis in mouse cortical culture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Biochemical characteristics of caspases-3, -6, -7, and -8

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Possible role of caspase-3 inhibition in cadmium-induced blockage of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptosis induced by cadmium in human lymphoma U937 cells through Ca2+-calpain and caspase-mitochondria- dependent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The role of arsenic-thiol interactions in metalloregulation of the ars operon

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A role for metals and free radicals in the induction of apoptosis in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-kappa B by TNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Mechanism of Dithiocarbamate Inhibition of Apoptosis: Thiol Oxidation by Dithiocarbamate Disulfides Directly Inhibits Processing of the Caspase-3 Proenzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Disulfiram is a potent inhibitor of proteases of the caspase family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Disulfiram inhibits TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

4-Hydroxynonenal inhibits interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of the conversion of pre-interleukins-1 alpha and 1 beta to mature cytokines by p-benzoquinone, a metabolite of benzene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Hydroquinone, a bioreactive metabolite of benzene, inhibits apoptosis in myeloblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

L-741,494, a fungal metabolite that is an inhibitor of interleukin-1 beta converting enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

EI-1507-1 and -2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1507

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. III. Biochemical properties of EI-1511-3, -5 and EI-1625-2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. II. Structure determination

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Thiophilic ring-opening and rearrangement reactions of epoxyketone natural products.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Novel cyclopentanone derivatives pentenocins A and B with interleukin-1beta converting enzyme inhibitory activity, produced by Trichoderma hamatum FO-6903

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin-1 beta converting enzyme (ICE)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Structure and mechanism of interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspases and caspase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Rapid optimization of an ICE inhibitor synthesis using multiple reaction conditions in a parallel array

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Peptidomimetic aminomethylene ketone inhibitors of interleukin-1 beta-converting enzyme (ICE)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Bimodal inhibition of caspase-1 by aryloxymethyl and acyloxymethyl ketones

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A catalytic mechanism for caspase-1 and for bimodal inhibition of caspase-1 by activated aspartic ketones

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inactivation of cysteine proteases by (acyloxy)methyl ketones using S'-P' interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Peptidyl beta-homo-aspartals: specific inhibitors of interleukin-1 beta converting enzyme and its homologues (caspases)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Peptide based interleukin-1 beta converting enzyme (ICE) inhibitors: synthesis, structure activity relationships and crystallographic study of the ICE-inhibitor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A substrate combinatorial array for caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Interleukin-1 beta converting enzyme: a novel cysteine protease required for IL-1 beta production and implicated in programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

First examples of peptidomimetic inhibitors of interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Conformationally constrained inhibitors of caspase-1 (interleukin-1 beta converting enzyme) and of the human CED-3 homologue caspase-3 (CPP32, apopain)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

The X-linked inhibitor of apoptosis (XIAP) prevents cell death in axotomized CNS neurons in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

IAP family proteins delay motoneuron cell death in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Long-term effect of inhibition of ced 3-like caspases on the survival of axotomized retinal ganglion cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Immunohistochemical investigation of caspase-1 and effect of caspase-1 inhibitor in delayed neuronal death after transient cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

In vivo myocardial infarct size reduction by a caspase inhibitor administered after the onset of ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Effect of caspase inhibitors on myocardial infarct size and myocyte DNA fragmentation in the ischemia-reperfused rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Inhibition of interleukin-1beta converting enzyme family proteases (caspases) reduces cold injury-induced brain trauma and DNA fragmentation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

A Synthetic Inhibitor of Interleukin-lβ Converting Enzyme Prevents Endotoxin-Induced Interleukin-lβ ProductionIn VitroandIn Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Fetal nigral transplantation as a therapy for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase inhibition reduces apoptosis and increases survival of nigral transplants

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Caspase inhibition increases embryonic striatal graft survival

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Design of a temporally and spatially controlled drug delivery system for the treatment of liver diseases in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Apoptosis in cerebellar granule neurones: involvement of interleukin-1 beta converting enzyme-like proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

Zinc-mediated reduction of apoptosis in cardiac allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970068-7

7 January 2021

10.1016/S0079-6468(08)70068-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12536670%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference