(Q35159929)

6 August 2017

title

Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction (English)

1 reference

protein-protein interaction

6 August 2017

main subject

1 reference

5

Adam Nelson

0 references

Andrew J. Wilson

7

Andrew J Wilson

0 references

Stuart L. Warriner

6

Stuart L Warriner

0 references

Thomas A Edwards

4

Thomas A Edwards

0 references

George M. Burslem

George M Burslem

1

0 references

Alexander L Breeze

Alexander L Breeze

3

0 references

author name string

Hannah F Kyle

2

1 reference

6 August 2017

publication date

29 April 2014

1 reference

full work available at URL

6 August 2017

http://eprints.whiterose.ac.uk/83418

content deliverer

White Rose Research Online

object has role

published version

1 reference

White Rose Research Online

http://eprints.whiterose.ac.uk/83418

15 December 2018

1 reference

6 August 2017

volume

15

1 reference

6 August 2017

issue

8

1 reference

6 August 2017

page(s)

1083-1087

1 reference

Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling.

6 August 2017

cites work

1 reference

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Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins

13 July 2018

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A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.

13 July 2018

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Solid-phase methodology for synthesis of O-alkylated aromatic oligoamide inhibitors of α-helix-mediated protein-protein interactions

13 July 2018

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Suppression of tumor growth by designed dimeric epidithiodiketopiperazine targeting hypoxia-inducible transcription factor complex.

13 July 2018

1 reference

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Allosteric inhibition of hypoxia inducible factor-2 with small molecules

13 July 2018

1 reference

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Inhibition of α-helix-mediated protein-protein interactions using designed molecules

13 July 2018

1 reference

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Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules

13 July 2018

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Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide α-helix mimetics

13 July 2018

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Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

13 July 2018

1 reference

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Modeling of arylamide helix mimetics in the p53 peptide binding site of hDM2 suggests parallel and anti-parallel conformations are both stable

13 July 2018

1 reference

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Fine-tuning multiprotein complexes using small molecules

13 July 2018

1 reference

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Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors.

13 July 2018

1 reference

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Structural biology and drug discovery of difficult targets: the limits of ligandability

13 July 2018

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Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway

13 July 2018

1 reference

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Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors

13 July 2018

1 reference

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Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor

13 July 2018

1 reference

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Hallmarks of Cancer: The Next Generation

13 July 2018

1 reference

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High Specificity in Protein Recognition by Hydrogen‐Bond‐Surrogate α‐Helices: Selective Inhibition of the p53/MDM2 Complex

13 July 2018

1 reference

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Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction

13 July 2018

1 reference

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Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix

13 July 2018

1 reference

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Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation

13 July 2018

1 reference

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Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site

13 July 2018

1 reference

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Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL.

13 July 2018

1 reference

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Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Modulation of p300 binding by posttranslational modifications of the C-terminal activation domain of hypoxia-inducible factor-1alpha

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

CREB-binding protein and p300 in transcriptional regulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

2-O-alkylated para-benzamide α-helix mimetics: the role of scaffold curvature.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

N-alkylated oligoamide alpha-helical proteomimetics

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Synthetic inhibitors of extended helix-protein interactions based on a biphenyl 4,4'-dicarboxamide scaffold

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Synthesis of functionalised aromatic oligamide rods

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Suppression of tumor growth through disruption of hypoxia-inducible transcription

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159589

Aromatic Oligoamide Foldamers with a “Wet Edge” as Inhibitors of the α-Helix-Mediated p53-hDM2 Protein-Protein Interaction

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FCBIC.201400009

21 January 2018

Identifiers

DOI

10.1002/CBIC.201400009

1 reference

Dimensions Publication ID

6 August 2017

Altmetric DOI

10.1002/CBIC.201400009

0 references

1010188651

0 references

Fatcat ID

release_xhk5qu3g3bf7zkwetumygw77bi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xhk5qu3g3bf7zkwetumygw77bi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4159589

1 reference

6 August 2017

1 reference