(Q35676307)

9 August 2017

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title

Novel aspects of macromolecular repair and relationship to human disease (English)

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9 August 2017

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1

Hans E Krokan

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9 August 2017

3

Geir Slupphaug

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9 August 2017

2

Bodil Kavli

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9 August 2017

publication date

24 February 2004

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Journal of Molecular Medicine

9 August 2017

published in

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9 August 2017

volume

82

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9 August 2017

issue

5

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9 August 2017

page(s)

280-297

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https://scigraph.springernature.com/pub.10.1007/s00109-004-0528-1

9 August 2017

exact match

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cites work

Aging as war between chemical and biochemical processes: Protein methylation and the recognition of age-damaged proteins for repair

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12 December 2020

Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

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12 December 2020

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

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12 December 2020

In vitro base excision repair assay using mammalian cell extracts

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12 December 2020

Bacteriophage T4 anticodon nuclease, polynucleotide kinase and RNA ligase reprocess the host lysine tRNA.

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12 December 2020

Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs

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12 December 2020

The mechanism of switching among multiple BER pathways.

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12 December 2020

Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins

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12 December 2020

Molecular chaperones: the busy life of Hsp90.

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Peptide methionine sulfoxide reductase: biochemistry and physiological role

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ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses.

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12 December 2020

Transcription-coupled repair deficiency and mutations in human mismatch repair genes

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12 December 2020

hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs

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12 December 2020

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12 December 2020

Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport

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12 December 2020

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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12 December 2020

Regulation of cell function by methionine oxidation and reduction

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12 December 2020

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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12 December 2020

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors

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12 December 2020

Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate

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12 December 2020

Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas

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12 December 2020

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

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12 December 2020

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

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12 December 2020

Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.

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12 December 2020

The sor gene of HIV-1 is required for efficient virus transmission in vitro

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12 December 2020

DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability

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12 December 2020

How nucleotide excision repair protects against cancer

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12 December 2020

Uracil in DNA--occurrence, consequences and repair

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12 December 2020

DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes.

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12 December 2020

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

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12 December 2020

Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

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12 December 2020

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

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12 December 2020

Review: mechanisms of disaggregation and refolding of stable protein aggregates by molecular chaperones

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12 December 2020

Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues

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12 December 2020

Cancer risks in A-T heterozygotes

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12 December 2020

Molecular mechanism of PCNA-dependent base excision repair

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12 December 2020

A quantitative model of human DNA base excision repair. I. Mechanistic insights

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12 December 2020

Mismatch repair in correction of replication errors and processing of DNA damage

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12 December 2020

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

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12 December 2020

DNA repair: how Ku makes ends meet.

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12 December 2020

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

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12 December 2020

Real-time kinetic analyses of the interaction of ricin toxin A-chain with ribosomes prove a conformational change involved in complex formation

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12 December 2020

Bloom's syndrome. XIX. Cytogenetic and population evidence for genetic heterogeneity.

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12 December 2020

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

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12 December 2020

Role of homologous recombination in carcinogenesis.

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12 December 2020

DNA repair activity for oxidative damage and risk of lung cancer

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12 December 2020

The mechanism and regulation of chromosomal V(D)J recombination

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12 December 2020

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

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12 December 2020

Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing

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12 December 2020

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

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12 December 2020

Quality control by DNA repair

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12 December 2020

Detecting, signalling and repairing DNA double-strand breaks.

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12 December 2020

Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain

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12 December 2020

Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase.

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12 December 2020

RNA repair: damage control

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12 December 2020

DNA mismatch repair and mutation avoidance pathways

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12 December 2020

Structure of a trapped endonuclease III-DNA covalent intermediate

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12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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12 December 2020

Selenoprotein Metabolism and Function: Evidence for More than One Function for Selenoprotein P

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12 December 2020

Limited accumulation of damaged proteins in l-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice.

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12 December 2020

Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA.

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12 December 2020

Mechanism and regulation of human non-homologous DNA end-joining

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12 December 2020

Choreography of oxidative damage repair in mammalian genomes

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12 December 2020

Oxidation of methionyl residues in proteins: tools, targets, and reversal

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12 December 2020

Sensing and repairing DNA double-strand breaks

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12 December 2020

AID mutant analyses indicate requirement for class-switch-specific cofactors

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12 December 2020

Rat peptide methionine sulphoxide reductase: cloning of the cDNA, and down-regulation of gene expression and enzyme activity during aging

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12 December 2020

Purification and substrate specificity of polydeoxyribonucleotide kinases isolated from calf thymus and rat liver

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12 December 2020

p53 and regulation of DNA damage recognition during nucleotide excision repair

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12 December 2020

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

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12 December 2020

DNA glycosylases in the base excision repair of DNA

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12 December 2020

Isoaspartate formation and neurodegeneration in Alzheimer's disease

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12 December 2020

Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme

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12 December 2020

RAG mutations in human B cell-negative SCID.

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12 December 2020

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

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12 December 2020

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells

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12 December 2020

Regulation and mechanisms of mammalian double-strand break repair

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12 December 2020

The Hsp90 chaperone complex as a novel target for cancer therapy

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12 December 2020

Age-dependent deamidation of asparagine residues in proteins

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12 December 2020

Transgenic expression of the protein-L-isoaspartyl methyltransferase (PIMT) gene in the brain rescues mice from the fatal epilepsy of PIMT deficiency

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12 December 2020

Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair

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12 December 2020

Base excision repair in nuclear and mitochondrial DNA.

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12 December 2020

The RNA Modification Database: 1999 update

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12 December 2020

Elevated homologous recombination activity in fanconi anemia fibroblasts

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12 December 2020

DNA deamination mediates innate immunity to retroviral infection

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12 December 2020

Role of DNA mismatch repair defects in the pathogenesis of human cancer

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12 December 2020

When repair meets chromatin. First in series on chromatin dynamics

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12 December 2020

Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair

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12 December 2020

The cytogenetics of ataxia telangiectasia

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12 December 2020

Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer

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12 December 2020

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

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12 December 2020

Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer

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12 December 2020

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

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12 December 2020

Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins

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12 December 2020

Biallelic inactivation of BRCA2 in Fanconi anemia

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12 December 2020

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

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12 December 2020

Eukaryotic DNA mismatch repair

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12 December 2020

Deamidation of human proteins

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12 December 2020

Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates

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12 December 2020

Intracellular localization of the 90 kDA heat shock protein (HSP90α) determined by expression of a EGFP—HSP90α‐fusion protein in unstressed and heat stressed 3T3 cells

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12 December 2020

Recent progress in the biology, chemistry and structural biology of DNA glycosylases

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12 December 2020

ATM and ATR: networking cellular responses to DNA damage

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12 December 2020

Altered aspartate in Alzheimer neurofibrillary tangles.

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12 December 2020

Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

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12 December 2020

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

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12 December 2020

Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis.

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12 December 2020

Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase

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12 December 2020

High-quality life extension by the enzyme peptide methionine sulfoxide reductase

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12 December 2020

The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications

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12 December 2020

Deamidation and isoaspartate formation in proteins: unwanted alterations or surreptitious signals?

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12 December 2020

Variant forms of DNA polymerase beta in primary lung carcinomas.

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12 December 2020

Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy

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12 December 2020

Down-regulation of protein L-isoaspartyl methyltransferase in human epileptic hippocampus contributes to generation of damaged tubulin

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12 December 2020

Life without DNA repair

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12 December 2020

Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA)

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12 December 2020

Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases

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12 December 2020

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations

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12 December 2020

Protein L-isoaspartyl methyltransferase in postmortem brains of aged humans

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12 December 2020

Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine

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12 December 2020

Pathways of DNA double-strand break repair during the mammalian cell cycle

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12 December 2020

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

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12 December 2020

A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

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12 December 2020

hRAD30 mutations in the variant form of xeroderma pigmentosum

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12 December 2020

Molecular chaperones in the cytosol: from nascent chain to folded protein

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12 December 2020

Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivo

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12 December 2020

DNA base excision repair of uracil residues in reconstituted nucleosome core particles

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12 December 2020

The interacting pathways for prevention and repair of oxidative DNA damage

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12 December 2020

A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans

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12 December 2020

Human genetic defects in class-switch recombination (hyper-IgM syndromes).

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12 December 2020

Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals

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12 December 2020

Base excision repair of DNA in mammalian cells

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12 December 2020

Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

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12 December 2020

Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair

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12 December 2020

DNA repair defects in colon cancer

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12 December 2020

Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

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12 December 2020

Instability and decay of the primary structure of DNA

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12 December 2020

HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation

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12 December 2020

The comings and goings of nucleotide excision repair factors on damaged DNA

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12 December 2020

The role of DNA breaks in genomic instability and tumorigenesis

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12 December 2020

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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12 December 2020

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

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12 December 2020

Involvement of the mismatch repair system in temozolomide-induced apoptosis

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12 December 2020

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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12 December 2020

Contribution of molecular chaperones to protein folding in the cytoplasm of prokaryotic and eukaryotic cells

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12 December 2020

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

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12 December 2020

Subpathways of nucleotide excision repair and their regulation

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12 December 2020

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

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12 December 2020

Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level

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12 December 2020

Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage

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12 December 2020

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

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12 December 2020

Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis

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12 December 2020

Base excision repair in yeast and mammals

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12 December 2020

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

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12 December 2020

Recognition of the codon-anticodon helix by ribosomal RNA.

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12 December 2020

DNA lesion recognition by the bacterial repair enzyme MutM

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12 December 2020

The HIV 'A' (sor) gene product is essential for virus infectivity

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12 December 2020

A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein

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12 December 2020

Molecular views of recombination proteins and their control

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12 December 2020

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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12 December 2020

Interactive competition between homologous recombination and non-homologous end joining

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12 December 2020

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

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12 December 2020

Conversion of alpha 1-antichymotrypsin into a human neutrophil elastase inhibitor: demonstration of variants with different association rate constants, stoichiometries of inhibition, and complex stabilities

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12 December 2020

Protein folding and its links with human disease

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12 December 2020

The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

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12 December 2020

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

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12 December 2020

p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage

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12 December 2020

Long-patch DNA repair synthesis during base excision repair in mammalian cells

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12 December 2020

Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome

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12 December 2020

Genome maintenance mechanisms for preventing cancer

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12 December 2020

10.1007/S00109-004-0528-1

Identifiers

DOI

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9 August 2017

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