(Q35769467)

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CD8+ effector cells

scientific article published on January 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

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Europe PubMed Central

CD8+ effector cells (English)

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Europe PubMed Central

PubMed publication ID

10 August 2017

author name string

Pierre A Henkart

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Marta Catalfamo

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

publication date

1 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Advances in Immunology

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Europe PubMed Central

PubMed publication ID

10 August 2017

83

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Europe PubMed Central

PubMed publication ID

10 August 2017

233-252

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

1 reference

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Cytolytic mechanisms and expression of activation-regulating receptors on effector-type CD8+CD45RA+CD27- human T cells.

1 reference

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7 January 2021

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Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

1 reference

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7 January 2021

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Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo

1 reference

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7 January 2021

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Cytotoxic T lymphocytes: all roads lead to death

1 reference

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7 January 2021

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Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

1 reference

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7 January 2021

based on heuristic

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Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks

1 reference

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7 January 2021

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Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

1 reference

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7 January 2021

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Enrichment and detection of live antigen-specific CD4(+) and CD8(+) T cells based on cytokine secretion

1 reference

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7 January 2021

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Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

1 reference

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7 January 2021

based on heuristic

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Functional differences between memory and naive CD8 T cells

1 reference

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7 January 2021

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Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

1 reference

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7 January 2021

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Detection of human cytokine-secreting cells in distinct anatomical compartments

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of cytotoxicity in lymphocyte homeostasis.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Th2 and Tc2 cells in the regulation of GVHD, GVL, and graft rejection: considerations for the allogeneic transplantation therapy of leukemia and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Noncytolytic control of viral infections by the innate and adaptive immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Phenotypic and functional separation of memory and effector human CD8+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of effector molecules on the CD8(+) T cell response to infection

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of adoptively transferred CD8 T cells and host cells in the control of the growth of the EG7 thymoma: factors that determine the relative effectiveness and homing properties of Tc1 and Tc2 effectors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of intracellular cytokines by flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Effector and memory T-cell differentiation: implications for vaccine development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation and proteolytic degradation of perforin within lytic granules upon neutralization of acidic pH

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Frequencies of circulating cytolytic, CD45RA+CD27-, CD8+ T lymphocytes depend on infection with CMV.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A transgenic mouse model to analyze CD8(+) effector T cell differentiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Preferential localization of effector memory cells in nonlymphoid tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Functions of CD8 T-cell subsets secreting different cytokine patterns.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Linear differentiation of cytotoxic effectors into memory T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Immediate early effector functions of virus-specific CD8+CCR7+ memory cells in humans defined by HLA and CC chemokine ligand 19 tetramers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphocyte-mediated cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The immunological synapse of CTL contains a secretory domain and membrane bridges.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulated secretion from hemopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional significance of the perforin/granzyme cell death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Functionally distinct CD8+ memory T cell subsets in persistent EBV infection are differentiated by migratory receptor expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: CCR7+ and CCR7- memory T cells do not differ in immediate effector cell function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization at the single-cell level of naive and primed CD8 T cell cytokine responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Lineage relationship and protective immunity of memory CD8 T cell subsets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-mediated killing: a common mechanism?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2804%2983007-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0065-2776(04)83007-4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

release_zej4kaaba5blpmlmxd4hjfmatq

1 reference

https://api.fatcat.wiki/v0/release/zej4kaaba5blpmlmxd4hjfmatq

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

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