(Q36637580)

15 August 2017

Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas (English)

1 reference

15 August 2017

Herbert C Morse

6

0 references

author name string

Monica Gostissa

1

1 reference

15 August 2017

Julia M Bianco

2

1 reference

15 August 2017

Daniel J Malkin

3

1 reference

15 August 2017

Jeffery L Kutok

4

1 reference

15 August 2017

Scott J Rodig

5

1 reference

15 August 2017

Craig H Bassing

7

1 reference

15 August 2017

Frederick W Alt

8

1 reference

15 August 2017

language of work or name

English

0 references

publication date

4 February 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

110

1 reference

15 August 2017

8

1 reference

15 August 2017

2934-2939

1 reference

Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomas

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Spatial organization of the mouse genome and its role in recurrent chromosomal translocations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

30 September 2017

p53: guardian of ploidy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Splenic marginal zone B-cell lymphoma: a distinct clinicopathological and molecular entity. Recent advances in ontogeny and classification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

New insights into the pathogenesis and treatment of Waldenstrom macroglobulinemia.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Mechanisms that promote and suppress chromosomal translocations in lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

AID and somatic hypermutation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

TP53 mutations in human cancers: origins, consequences, and clinical use

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Tumor protein 53 mutations and inherited cancer: beyond Li-Fraumeni syndrome.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Blinded by the Light: The Growing Complexity of p53

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Molecular mechanisms of antibody somatic hypermutation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Probing p53 biological functions through the use of genetically engineered mouse models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Extrafollicular antibody responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Mechanisms of chromosomal translocations in B cell lymphomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Cellular origin of human B-cell lymphomas.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Splenic marginal zone lymphomas of mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Tumor spectrum analysis in p53-mutant mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Bethesda proposals for classification of lymphoid neoplasms in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

Identification of murine germinal center B cell subsets defined by the expression of surface isotypes and differentiation antigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

Analysis of the B-cell progenitor compartment at the level of single cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222570110

Splenic marginal zone lymphoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581964

Insight into the molecular pathogenesis of hairy cell leukaemia, hairy cell leukaemia variant and splenic marginal zone lymphoma, provided by the analysis of their IGH rearrangements and somatic hypermutation patterns

21 October 2018

1 reference

12 December 2020

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

1 reference

12 December 2020

Effects of genetic background on tumorigenesis in p53-deficient mice

1 reference

12 December 2020

Splenic marginal zone B-cell and thymic T-cell lymphomas in p53-deficient mice

1 reference

12 December 2020

Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1222570110

1 reference

15 August 2017

0 references

1 reference

15 August 2017

PubMed publication ID

23382223

1 reference