(Q36845690)

16 August 2017

1 reference

title

Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies (English)

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16 August 2017

1 reference

4

Alain Fischer

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Sophie Peron

object named as

Sophie Peron

series ordinal

3

0 references

Anne Durandy

object named as

Anne Durandy

series ordinal

1

0 references

Nadine Taubenheim

series ordinal

2

object named as

Nadine Taubenheim

1 reference

16 August 2017

1 January 2007

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16 August 2017

Advances in Immunology

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16 August 2017

94

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16 August 2017

275-306

1 reference

Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome

16 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

C4b-Binding Protein (C4BP) Activates B Cells through the CD40 Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

TACI is mutant in common variable immunodeficiency and IgA deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

CD40 regulates the processing of NF-kappaB2 p100 to p52

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Induction by anti-CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X-linked hyper IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Activation-induced cytidine deaminase: structure-function relationship as based on the study of mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

T-Independent immune response: new aspects of B cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Identification and cloning of genes expressed by human tonsillar B lymphocyte subsets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Unmutated immunoglobulin M can protect mice from death by influenza virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

AID: how does it aid antibody diversity?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Immunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Circular DNA is excised by immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Indirect and direct evidence for DNA double-strand breaks in hypermutating immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Unique and unprecedented recombination mechanisms in class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Linking class-switch recombination with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Germinal center founder cells display propensity for apoptosis before onset of somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Characterization of a 23-kDa protein associated with CD40

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The transcriptional programme of antibody class switching involves the repressor Bach2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Analysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The AID enzyme induces class switch recombination in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The influence of transcriptional orientation on endogenous switch region function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Cis-acting sequences that affect somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Identification of a specific domain required for dimerization of activation-induced cytidine deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

B-1a B cells that link the innate and adaptive immune responses are lacking in the absence of the spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Evolution of autoantibody responses via somatic hypermutation outside of germinal centers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The double-edged sword of activation-induced cytidine deaminase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2994009-7

7 January 2021

10.1016/S0065-2776(06)94009-7

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17560278