(Q36846922)

16 August 2017

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title

Genomic profiling in nuclear receptor-mediated toxicity (English)

1 reference

16 August 2017

Courtney G Woods

1

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16 August 2017

John P Vanden Heuvel

series ordinal

2

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16 August 2017

Ivan Rusyn

series ordinal

3

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16 August 2017

language of work or name

English

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publication date

1 June 2007

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16 August 2017

published in

Toxicologic Pathology

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16 August 2017

volume

35

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16 August 2017

issue

4

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16 August 2017

page(s)

474-494

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New pharmacological perspectives and therapeutic potential of PPAR-gamma agonists

16 August 2017

cites work

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Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription

21 January 2018

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Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors

21 January 2018

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Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor, and liver X receptor in mouse liver.

21 January 2018

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Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

21 January 2018

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Comparative effects of TCDD, endrin, naphthalene and chromium (VI) on oxidative stress and tissue damage in the liver and brain tissues of mice

21 January 2018

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Clofibrate-induced gene expression changes in rat liver: a cross-laboratory analysis using membrane cDNA arrays

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Hepatic peroxisome proliferation in rodents and its significance for humans

21 January 2018

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Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor

21 January 2018

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Orphan nuclear receptors--new ligands and new possibilities.

21 January 2018

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Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor.

21 January 2018

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Consideration of both genotoxic and nongenotoxic mechanisms in predicting carcinogenic potential

21 January 2018

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Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Report of the Expert Panel on Population Strategies for Blood Cholesterol Reduction. A statement from the National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

The systemic reaction during inflammation: the acute-phase proteins

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

A transcriptional co-repressor that interacts with nuclear hormone receptors

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

The Human Genome Project: Lessons from Large-Scale Biology

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230701311351

Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Gene ontology mapping as an unbiased method for identifying molecular pathways and processes affected by toxicant exposure: application to acute effects caused by the rodent non-genotoxic carcinogen diethylhexylphthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Effects of the peroxisome proliferator mono(2-ethylhexyl)phthalate in primary hepatocyte cultures derived from rat, guinea pig, rabbit and monkey. Relationship between interspecies differences in biotransformation and peroxisome proliferating potenc

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Tumor-promoting and hepatocarcinogenic effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in DBA/2NCr and C57BL/6NCr mice and an apparent promoting effect on nasal cavity tumors but not on hepatocellular tumors in F344/NCr rats initiate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Differential display in rat livers treated for 13 weeks with phenobarbital implicates a role for metabolic and oxidative stress in nongenotoxic carcinogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: a microarray study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Mechanism of action of the nongenotoxic peroxisome proliferators: role of the peroxisome proliferator-activator receptor alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

A physical map of the mouse genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Enhanced acetaminophen toxicity by activation of the pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The aryl hydrocarbon receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Liver deformation in Ahr-null mice: evidence for aberrant hepatic perfusion in early development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

EDGE: a centralized resource for the comparison, analysis, and distribution of toxicogenomic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Activation of the Ah receptor by tryptophan and tryptophan metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Cytoplasmic TSC-22 (transforming growth factor-beta-stimulated clone-22) markedly enhances the radiation sensitivity of salivary gland cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Coordinate up-regulation of CYP1A1 and heme oxygenase-1 (HO-1) expression and modulation of delta-aminolevulinic acid synthase and tryptophan pyrrolase activities in pyridine-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

LXR-dependent gene expression is important for macrophage survival and the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

LXRS and FXR: the yin and yang of cholesterol and fat metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Abnormal spermatogenesis in RXR beta mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

PPARalpha agonist-induced rodent tumors: modes of action and human relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The role of oxidative stress in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Orphan nuclear receptors: shifting endocrinology into reverse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The carcinogenicity of dietary di(2-ethylhexyl) phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Effects of 3-methylcholanthrene on gene expression profiling in the rat using cDNA microarray analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

CAR and PXR: xenosensors of endocrine disrupters?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Identification of 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive genes in mouse liver by serial analysis of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Promoting effect of peroxisome proliferators in two-stage rat renal tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Development of hepatocellular carcinomas and increased peroxisomal fatty acid beta-oxidation in rats fed [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (Wy-14,643) in the semipurified diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

PPARdelta regulates glucose metabolism and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Application of comparative functional genomics to identify best-fit mouse models to study human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Roles of PPAR delta in lipid absorption and metabolism: a new target for the treatment of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The RXR heterodimers and orphan receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The nuclear receptor superfamily: the second decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Cancer mortality among workers in chemical plant contaminated with dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Characterization of an acute molecular marker of nongenotoxic rodent hepatocarcinogenesis by gene expression profiling in a long term clofibric acid study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The role of cholesterol and statins in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Effect on the expression of c-met, c-myc and PPAR-alpha in liver and liver tumors from rats chronically exposed to the hepatocarcinogenic peroxisome proliferator WY-14,643.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Functional role of AhR in the expression of toxic effects by TCDD

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Molecular responses to xenoestrogens: mechanistic insights from toxicogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Use of the nuclear receptor PXR to predict drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Functional and structural comparison of PXR and CAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The hepatic transcriptome as a window on whole-body physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Enterohepatic transport of bile salts and genetics of cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

PPAR(gamma) and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The transcriptional signature of dioxin in human hepatoma HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Differential regulation of FGF-2 and FGFR-1 in rat cortical astrocytes by dexamethasone and isoproterenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Impact of dioxin-type induction of drug-metabolizing enzymes on the metabolism of endo- and xenobiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The identification of ligand features essential for PXR activation by pharmacophore modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Retinoid x receptor heterodimers in the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

A ligand for the aryl hydrocarbon receptor isolated from lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Binding of ligands and activation of transcription by nuclear receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Gene expression profiling of potential peroxisome proliferator-activated receptor (PPAR) target genes in human hepatoblastoma cell lines inducibly expressing different PPAR isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Over-expression of TSC-22 (TGF-beta stimulated clone-22) markedly enhances 5-fluorouracil-induced apoptosis in a human salivary gland cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Comprehensive analysis of gene expression in rat and human hepatoma cells exposed to the peroxisome proliferator WY14,643

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Thiazolidinediones: a review of their mechanisms of insulin sensitization, therapeutic potential, clinical efficacy, and tolerability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Subchronic exposure to TCDD, PeCDF, PCB126, and PCB153: effect on hepatic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Dynamic gene expression changes precede dioxin-induced liver pathogenesis in medaka fish

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Identifying toxic mechanisms using DNA microarrays: evidence that an experimental inhibitor of cell adhesion molecule expression signals through the aryl hydrocarbon nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Phenobarbital induction of cytochrome P-450 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Phenobarbital mechanistic data and risk assessment: enzyme induction, enhanced cell proliferation, and tumor promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of L

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701311351

10.1080/01926230701311351

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference