(Q36881600)

16 August 2017

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title

Targeting mast cells in endometriosis with janus kinase 3 inhibitor, JANEX-1. (English)

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16 August 2017

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2

Fatih M Uckun

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16 August 2017

Osmond J D'Cruz

1

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16 August 2017

publication date

1 August 2007

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American Journal of Reproductive Immunology

16 August 2017

published in

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16 August 2017

volume

58

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16 August 2017

issue

2

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16 August 2017

page(s)

75-97

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Endometriosis: abnormal endometrium and dysfunctional immune response.

16 August 2017

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Marked elevation of macrophage migration inhibitory factor in the peritoneal fluid of women with endometriosis

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Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis.

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Peritoneal fluid concentrations of epithelial neutrophil-activating peptide-78 correlate with the severity of endometriosis.

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Tumor necrosis factor-alpha but not interleukin-1 beta or interleukin-8 concentrations correlate with angiogenic activity of peritoneal fluid from patients with minimal to mild endometriosis.

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Endometriosis and unexplained recurrent spontaneous abortion: pathological states resulting from aberrant modulation of natural killer cell function?

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The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis

21 January 2018

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Cardiac risks with COX-2 inhibitors

21 January 2018

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The coxibs and traditional nonsteroidal anti-inflammatory drugs: a current perspective on cardiovascular risks

21 January 2018

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Cardiovascular toxicities of immunosuppressive agents

21 January 2018

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Developments in glucocorticoid therapy

21 January 2018

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Induction of endometriosis in mice: A new model sensitive to estrogen

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Peritoneal endometriosis: validation of an in-vivo model

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Record review of baboons with histologically confirmed endometriosis in a large established colony

21 January 2018

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Increased numbers of activated mast cells in endometriosis lesions positive for corticotropin-releasing hormone and urocortin

21 January 2018

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Light and electron microscopic evaluation of antileukotriene therapy for experimental rat endometriosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Integrated signalling pathways for mast-cell activation

21 January 2018

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The role of Th2 cytokines in mast cell homeostasis

21 January 2018

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Stat5 expression is required for IgE-mediated mast cell function

21 January 2018

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Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Genetic and biochemical evidence for a critical role of Janus kinase (JAK)-3 in mast cell-mediated type I hypersensitivity reactions

21 January 2018

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Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

21 January 2018

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Prevention of CD40-triggered dendritic cell maturation and induction of T-cell hyporeactivity by targeting of Janus kinase 3.

21 January 2018

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Suppression of early T-cell-receptor-triggered cellular activation by the Janus kinase 3 inhibitor WHI-P-154.

21 January 2018

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Targeting JAK3 with JANEX-1 for prevention of autoimmune type 1 diabetes in NOD mice

21 January 2018

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Dual targeting of Bruton's tyrosine kinase and Janus kinase 3 with rationally designed inhibitors prevents graft-versus-host disease (GVHD) in a murine allogeneic bone marrow transplantation model

21 January 2018

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Nitric Oxide Modulates Pro- and Anti-inflammatory Cytokines in Lipopolysaccharide-Activated Macrophages

21 January 2018

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The kinase inhibitor imatinib mesylate inhibits TNF-{alpha} production in vitro and prevents TNF-dependent acute hepatic inflammation

21 January 2018

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Anti-inflammatory activity of 2,4, 6-trihydroxy-alpha-p-methoxyphenyl-acetophenone (compound D-58).

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse.

21 January 2018

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Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

New trends in immunosuppression

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Janus kinase 3: a novel target for selective transplant immunosupression

21 January 2018

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The novel JAK-3 inhibitor CP-690550 is a potent immunosuppressive agent in various murine models

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Effects of JAK3 inhibition with CP-690,550 on immune cell populations and their functions in nonhuman primate recipients of kidney allografts

21 January 2018

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Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

21 January 2018

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Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

PNU156804 inhibits Jak3 tyrosine kinase and rat heart allograft rejection

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The levonorgestrel-releasing intrauterine system in modern gynaecology

21 January 2018

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ESHRE guideline for the diagnosis and treatment of endometriosis

21 January 2018

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Mechanisms of endotoxin shock and endotoxin hypersensitivity

21 January 2018

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The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3

21 January 2018

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ENDOMETRIOSIS AND OVULATORY DISORDER: REDUCED FERTILISATION IN VITRO COMPARED WITH TUBAL AND UNEXPLAINED INFERTILITY

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms in endometriosis

21 January 2018

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10.1111/J.1600-0897.2007.00502.X

21 January 2018

Identifiers

DOI

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16 August 2017

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