(Q37120161)

18 August 2017

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title

Stem and progenitor cell-mediated tumor selective gene therapy (English)

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18 August 2017

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K S Aboody

1

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18 August 2017

J Najbauer

series ordinal

2

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18 August 2017

M K Danks

series ordinal

3

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18 August 2017

language of work or name

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27 March 2008

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18 August 2017

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18 August 2017

volume

15

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18 August 2017

issue

10

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18 August 2017

page(s)

739-752

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https://scigraph.springernature.com/pub.10.1038/gt.2008.41

18 August 2017

exact match

0 references

cites work

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Gene therapy of experimental brain tumors using neural progenitor cells

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Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas

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Transplantation of prodrug-converting neural progenitor cells for brain tumor therapy

21 January 2018

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In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Interleukin-23-expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Targeting of melanoma brain metastases using engineered neural stem/progenitor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Novel method for visualizing and modeling the spatial distribution of neural stem cells within intracranial glioma

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Development of a tumor-selective approach to treat metastatic cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Intravascular administration of tumor tropic neural progenitor cells permits targeted delivery of interferon-beta and restricts tumor growth in a murine model of disseminated neuroblastoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.41

Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human mesenchymal stem cells as a gene delivery system to create cardiac pacemakers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Stem cell therapies for malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

GDNF delivery using human neural progenitor cells in a rat model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Stem cells as vehicles for the treatment of brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Biophysical aspects of using liposomes as delivery vehicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Organically modified silica nanoparticles: a nonviral vector for in vivo gene delivery and expression in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Engineering targeted viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Enhancement of gene transfer to cervical cancer cells using transferrin-conjugated liposome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Conjugation of an anti transferrin receptor IgG3-avidin fusion protein with biotinylated saporin results in significant enhancement of its cytotoxicity against malignant hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Downregulation of transferrin receptor surface expression by intracellular antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Intravenous siRNA of brain cancer with receptor targeting and avidin-biotin technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Stem cell factor is a chemoattractant and a survival factor for CNS stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Neural stem cell migration toward gliomas in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Brain tumor tropism of transplanted human neural stem cells is induced by vascular endothelial growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

MCP-1 induces migration of adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

High mobility group box 1 protein, a cue for stem cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix Metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Glioma-produced extracellular matrix influences brain tumor tropism of human neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Prodrug activation enzymes in cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Viral vectors for gene delivery to the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Enzyme-catalyzed activation of anticancer prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Fusion of the HSV-1 tegument protein vp22 to cytosine deaminase confers enhanced bystander effect and increased therapeutic benefit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Topoisomerase I inhibitors: camptothecins and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

HSV amplicon vectors for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human neural stem cells genetically modified for brain repair in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Brain transplantation of human neural stem cells transduced with tyrosine hydroxylase and GTP cyclohydrolase 1 provides functional improvement in animal models of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Genetically engineered human neural stem cells for brain repair in neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Cell-to-cell fusion as a link between viruses and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Induction of pluripotent stem cells from fibroblast cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Dental pulp cells provide neurotrophic support for dopaminergic neurons and differentiate into neurons in vitro; implications for tissue engineering and repair in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human fetal mesenchymal stem cells as vehicles for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Generation of human cortical neurons from a new immortal fetal neural stem cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Brain transplantation of immortalized human neural stem cells promotes functional recovery in mouse intracerebral hemorrhage stroke model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Telomerase immortalization of human neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Telomerase extends a helping hand to progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Successful immortalization of mesenchymal progenitor cells derived from human placenta and the differentiation abilities of immortalized cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Improving cell therapy--experiments using transplanted telomerase-immortalized cells in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Chromosomal instability in human mesenchymal stem cells immortalized with human papilloma virus E6, E7, and hTERT genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Constructing immortalized human cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Ectopic telomerase expression inhibits neuronal differentiation of NT2 neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Resilience to transformation and inherent genetic and functional stability of adult neural stem cells ex vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Changing potency by spontaneous fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Cell fusion-independent differentiation of neural stem cells to the endothelial lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Mesenchymal stem cells are recruited to striated muscle by NFAT/IL-4-mediated cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Neural progenitor cells lack immunogenicity and resist destruction as allografts. 2003.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

A novel means of drug delivery: myoblast-mediated gene therapy and regulatable retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Vector-producing tumor-tracking multipotent mesenchymal stromal cells for suicide cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Helper virus-free herpes simplex virus type 1 amplicon vectors for granulocyte-macrophage colony-stimulating factor-enhanced vaccination therapy for experimental glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Introduction to the background, principles, and state of the art in suicide gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Clinical trials using irinotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Interleukin-4 enhances the in vitro precursor cell recruitment for tumor-specific T lymphocytes in patients with glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Interleukin-12-based immunotherapy against rat 9L glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Safety and antitumor activity of recombinant soluble Apo2 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Anti-tumor activity of mesenchymal stem cells producing IL-12 in a mouse melanoma model

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Carcinogenesis driven by bone marrow-derived stem cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer Agents

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Bone marrow cells engraft within the epidermis and proliferatein vivo with no evidence of cell fusion

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Adeno-associated viral vector transduction of human mesenchymal stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.41

7 January 2021

Identifiers

DOI

10.1038/GT.2008.41

1 reference

Dimensions Publication ID

18 August 2017

1053445008

0 references

1 reference