(Q37258521)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Scott H Kaufmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

X Wei Meng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Sun-Hee Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Paula A Schneider

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

language of work or name

English

0 references

publication date

7 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

18311-18322

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

25 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2709361/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

1 reference

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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.

6 September 2017

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BAX activation is initiated at a novel interaction site

6 September 2017

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Bcl-XL inhibits membrane permeabilization by competing with Bax.

6 September 2017

1 reference

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

6 September 2017

1 reference

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Expression and purification of recombinant annexin V for the detection of membrane alterations on apoptotic cells

6 September 2017

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Diagnosing and exploiting cancer's addiction to blocks in apoptosis

6 September 2017

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6 September 2017

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6 September 2017

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Bcl-2-regulated apoptosis: mechanism and therapeutic potential

6 September 2017

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Structural insights into the degradation of Mcl-1 induced by BH3 domains

6 September 2017

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Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Rapid turnover of mcl-1 couples translation to cell survival and apoptosis

6 September 2017

1 reference

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The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site

6 September 2017

1 reference

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Bcl-2 gene expression as a predictor of outcome in diffuse large B-cell lymphoma

6 September 2017

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

6 September 2017

1 reference

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How the Bcl-2 family of proteins interact to regulate apoptosis.

6 September 2017

1 reference

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Life in the balance: how BH3-only proteins induce apoptosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

6 September 2017

1 reference

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BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

6 September 2017

1 reference

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Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Cytochrome C-mediated apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Divergence of Genbank and human tumor Bcl-2 sequences and implications for binding affinity to key apoptotic proteins

6 September 2017

1 reference

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VDAC2 inhibits BAK activation and mitochondrial apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

6 September 2017

1 reference

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BH3 domains: intracellular death-ligands critical for initiating apoptosis

6 September 2017

1 reference

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The Bcl2 family: regulators of the cellular life-or-death switch

6 September 2017

1 reference

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

6 September 2017

1 reference

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Solution structure of the antiapoptotic protein bcl-2

6 September 2017

1 reference

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Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Induction of apoptosis by the Bcl-2 homologue Bak

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Social controls on cell survival and cell death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

S-peptide epitope tagging for protein purification, expression monitoring, and localization in mammalian cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Central role of Fas-associated death domain protein in apoptosis induction by the mitogen-activated protein kinase kinase inhibitor CI-1040 (PD184352) in acute lymphocytic leukemia cells in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Electroporation in ‘intracellular’ buffer increases cell survival

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

An informatics approach identifying markers of chemosensitivity in human cancer cell lines.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709361

Involvement of the bcl-2 gene in human follicular lymphoma

3 September 2018

1 reference

12 December 2020

Biosensors. Surface plasmon resonance lights the way

1 reference

12 December 2020

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

12 December 2020

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.004770

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351886%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference